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Trends in the pharmacological management of atrial fibrillation in UK general practice 2008-2018
Conclusions There has been an increase in the proportion of patients with AF appropriately prescribed anticoagulants following National Institute for Health and Care Excellence and European Society of Cardiology guidelines, which correlates with improvements in mortality and stroke outcomes. Beta-blockers appear increasingly favoured over digoxin for rate control. There has been a steady decline in GP prescribing rates for rhythm control drugs, possibly related to concerns over efficacy and safety and increased availability of AF ablation.
Source: Heart - March 10, 2022 Category: Cardiology Authors: Phillips, K., Subramanian, A., Thomas, G. N., Khan, N., Chandan, J. S., Brady, P., Marshall, T., Nirantharakumar, K., Fabritz, L., Adderley, N. J. Tags: Arrhythmias and sudden death Source Type: research

Heartbeat: Highlights from the issue
In this issue of Heart, Dr. Bouri and colleagues (see page 456) reexamined the issue of the perioperative use of beta blockers in patients with an intermediate or high cardiovascular risk who are undergoing major non cardiac surgery. Unfortunately, the evidence base for current recommendations has been called into question because of allegations of research fraud in some of the main studies, which are excluded from this new meta-analysis of the relevant randomized controlled clinical trials. They found that although beta-blockers decreased the risk of non-fatal myocardial infarction, they increased the risk of stroke and h...
Source: Heart - February 19, 2014 Category: Cardiology Authors: Otto, C. M. Tags: Drugs: cardiovascular system, Interventional cardiology, Acute coronary syndromes, Epidemiology Heartbeat Source Type: research

Meta-analysis of secure randomised controlled trials of {beta}-blockade to prevent perioperative death in non-cardiac surgery
Conclusions Guideline bodies should retract their recommendations based on fictitious data without further delay. This should not be blocked by dispute over allocation of blame. The well-conducted trials indicate a statistically significant 27% increase in mortality from the initiation of perioperative β-blockade that guidelines currently recommend. Any remaining enthusiasts might best channel their energy into a further randomised trial which should be designed carefully and conducted honestly.
Source: Heart - February 19, 2014 Category: Cardiology Authors: Bouri, S., Shun-Shin, M. J., Cole, G. D., Mayet, J., Francis, D. P. Tags: Open access, Drugs: cardiovascular system, Echocardiography, Interventional cardiology, Acute coronary syndromes, Clinical diagnostic tests, Epidemiology Cardiac risk factors and prevention Source Type: research