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Design, Synthesis, and Biological Evaluation of New ALDH2 Activators
In this study, three new classes of compounds were modified from Alda-1 to improve their water-solubility and then drug-like properties. The results showed that all compounds had increased water solubility and two classes of compounds exhibited good activation activity. Among them, compound I-6 showed the best activity.
Source: Journal of Saudi Chemical Society - July 19, 2018 Category: Chemistry Source Type: research
