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Bavituximab decreases immunosuppressive myeloid-derived suppressor cells in newly diagnosed glioblastoma patients
DISCUSSION: Bavituximab has activity in newly diagnosed GBM and resulted in on-target depletion of intratumoral immunosuppressive MDSCs. Elevated pre-treatment expression of myeloid-related transcripts in GBM may predict response to bavituximab.PMID:37327319 | DOI:10.1158/1078-0432.CCR-23-0203
Source: Clinical Cancer Research - June 16, 2023 Category: Cancer & Oncology Authors: K Ina Ly Leland G Richardson Mofei Liu Alona Muzikansky Jonathan Cardona Kevin Lou Andrew L Beers Ken Chang James M Brown Xiaoyue Ma David A Reardon Isabel C Arrillaga-Romany Deborah A Forst Justin T Jordan Eudocia Q Lee Jorg Dietrich Lakshmi Nayak Patric Source Type: research
