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Comparative Effectiveness and Safety Between Apixaban, Dabigatran, Edoxaban, and Rivaroxaban Among Patients With Atrial Fibrillation : A Multinational Population-Based Cohort Study
CONCLUSION: Among patients with AF, apixaban use was associated with lower risk for GIB and similar rates of ischemic stroke or systemic embolism, ICH, and all-cause mortality compared with dabigatran, edoxaban, and rivaroxaban. This finding was consistent for patients aged 80 years or older and those with chronic kidney disease, who are often underrepresented in clinical trials.PRIMARY FUNDING SOURCE: None.PMID:36315950 | DOI:10.7326/M22-0511
Source: Annals of Internal Medicine - October 31, 2022 Category: Internal Medicine Authors: Wallis C Y Lau Carmen Olga Torre Kenneth K C Man Henry Morgan Stewart Sarah Seager Mui Van Zandt Christian Reich Jing Li Jack Brewster Gregory Y H Lip Aroon D Hingorani Li Wei Ian C K Wong Source Type: research

Risk for Myocardial Infarction, Stroke, and Pulmonary Embolism Following COVID-19 Vaccines in Adults Younger Than 75 Years in France
CONCLUSION: In persons aged 18 to 74 years, adenoviral-based vaccines may be associated with increased incidence of MI and PE. No association between mRNA-based vaccines and the cardiovascular events studied was observed.PRIMARY FUNDING SOURCE: None.PMID:35994748 | DOI:10.7326/M22-0988
Source: Annals of Internal Medicine - August 22, 2022 Category: Internal Medicine Authors: J érémie Botton Marie Joelle Jabagi Marion Bertrand B érangère Baricault J érôme Drouin St éphane Le Vu Alain Weill Paddy Farrington Mahmoud Zureik Rosemary Dray-Spira Source Type: research

Risk for Recurrent Venous Thromboembolism in Patients With Subsegmental Pulmonary Embolism Managed Without Anticoagulation : A Multicenter Prospective Cohort Study
CONCLUSION: Overall, patients with subsegmental pulmonary embolism who did not have proximal deep venous thrombosis had a higher-than-expected rate of recurrent venous thromboembolism.PRIMARY FUNDING SOURCE: Heart and Stroke Foundation of Canada and French Ministry of Health Programme Hospitalier de Recherche Clinique.PMID:34807722 | DOI:10.7326/M21-2981
Source: Annals of Internal Medicine - November 22, 2021 Category: Internal Medicine Authors: Gr égoire Le Gal Michael J Kovacs Laurent Bertoletti Francis Couturaud Carole Dennie Andrew M Hirsch Menno V Huisman Frederikus A Klok No émie Kraaijpoel Ranjeeta Mallick Amanda Pecarskie Elena Pena Penny Phillips Isabelle Pichon Tim Ramsay Marc Righini Source Type: research

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