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Source: BMJ Open
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Total 87 results found since Jan 2013.

Effect of robotic-assisted gait training on gait and motor function in spinal cord injury: a protocol of a systematic review with meta-analysis
Introduction Robotic-assisted gait training (RAGT) has been reported to be effective in rehabilitating patients with spinal cord injury (SCI). However, studies on RAGT showed different results due to a varied number of samples. Thus, summarising studies based on robotic-related factors is critical for the accurate estimation of the effects of RAGT on SCI. This work aims to search for strong evidence showing that using RAGT is effective in treating SCI and analyse the deficiencies of current studies. Methods and analysis The following publication databases were electronically searched in December 2022 without restrictions ...
Source: BMJ Open - September 22, 2023 Category: General Medicine Authors: Wang, L., Peng, J.-l., Chen, A.-l. Tags: Open access, Rehabilitation medicine Source Type: research

Effects of PCSK9 inhibitors on coronary microcirculation, inflammation and cardiac function in patients with CHD after PCI: a protocol for systematic review and meta-analysis
This study is a systematic review of published literature data and no special ethical approval was required. PROSPERO registration number CRD42022346189.
Source: BMJ Open - September 18, 2023 Category: General Medicine Authors: Ye, X., Wang, S., Liu, X., Wu, Q., Lv, Y., Lv, Q., Li, J., Li, L., Yang, Y. Tags: Open access, Cardiovascular medicine Source Type: research

Supportive care needs of patients who had a stroke: a scoping review protocol
Introduction Incidences of stroke are on the rise and approximately 80 million stroke survivors worldwide live with disabilities. Supportive care needs of stroke survivors are not adequately defined, and the assessment tools to help care service providers identify these needs are unclear. The overall aim of this scoping review will be to map the supportive care needs of stroke survivors against the Supportive Care Needs Framework. Methods and analysis This scoping review will be conducted following Arksey and O’Malley’s methodological framework and Joanna Briggs Institute (JBI) updated methodological guidance ...
Source: BMJ Open - August 24, 2023 Category: General Medicine Authors: Zhang, H., Xu, K., Ma, J. Y., Zhang, X. Y., Sun, Y. Y., Xiao, L. D., Yan, F., Luo, Y. Y., Tang, S. Tags: Open access, Health services research Source Type: research

Efficacy and safety of acupuncture in the treatment of urinary incontinence after prostate surgery: protocol for a systematic review and meta-analysis
Background Urinary incontinence (UI) is a common complication after prostate surgery. Acupuncture treatment (AT) has been proposed as an alternative therapy for this condition. The purpose of this protocol aims to outline a systematic review and meta-analysis that aims to evaluate the effectiveness and safety of AT in patients with postprostate surgery UI. Methods We will search for randomised controlled trials (RCTs) in eight databases including PubMed, Embase, Cochrane Library, Web of Science, China National Knowledge Infrastructure, Wanfang database, SinoMed and VIP database. Additionally, we will search two clinical t...
Source: BMJ Open - August 18, 2023 Category: General Medicine Authors: Tan, M.-Y., Mo, C.-Y., Zhao, Q. Tags: Open access, Complementary medicine Source Type: research

Effectiveness of acceptance and commitment therapy in patients who had a stroke: a systematic review protocol
This study aimed to systematically evaluate the intervention effect of ACT in patients who had a stroke, which may provide further clinical evidence. Methods and analysis A systematic search of databases, including CNKI, WanFang Data, VIP, CBM, PubMed, Embase, Cochrane Library, CINAHL and APA PsycArticles, will be conducted from their inception to 31 October 2022. All randomised controlled trials, quasi-experiments and case studies relevant to ACT will be included in English and Chinese. Two independent reviewers will conduct the review, with data extraction and quality evaluation. Review Manager V.5.4 will be used to ass...
Source: BMJ Open - August 17, 2023 Category: General Medicine Authors: Xu, K., Zhang, X. Y., Ma, J. Y., Guo, X., Zhu, S.-S., Zhang, H., Sun, Y. Y. Tags: Open access, Mental health Source Type: research

Effects of virtual reality for psychological health of ICU patients: a study protocol for systematic review and meta-analysis
This study follows the Preferred Reporting Items for Systematic Review and Meta-analysis Protocols guidelines. Electronic data search is carried out on PubMed, Web of Science, CINAHL, EBSCO, EMBASE, Cochrane Library, PsycINFO, China National Knowledge Infrastructure, Wan Fang, VIP and Chinese Biology Medicine Database. The inclusion criteria follow the PICO principle, wherein ICU patients who have been hospitalised for 24 hours or more are included. Studies using VR-based interventions to improve the psychological health of ICU patients, compared with waitlist controls or traditional therapy groups; outcome assessments con...
Source: BMJ Open - July 21, 2023 Category: General Medicine Authors: Zou, J., Chen, Q., Wang, J., Gu, M., Jiang, X., Mao, M. Tags: Open access, Mental health Source Type: research

Reproductive concerns among young adult women with breast cancer: a systematic review protocol
Introduction Reproductive concerns refer to worries about impaired or lost reproductive ability due to disease or/and treatment. Many young female patients with breast cancer experience reproductive concerns because they still desire to have children at the time of diagnosis. Reproductive concerns can impact patients’ treatment decision-making as well as their psychological health and quality of life. Understanding the situation, contributing factors and health-related consequences of reproductive concerns among patients with breast cancer is essential to minimise their impacts. Methods and analysis A systematic rev...
Source: BMJ Open - July 14, 2023 Category: General Medicine Authors: Hu, L., Xu, B., Chau, P. H., Choi, E. P. H. Tags: Open access, Nursing Source Type: research

Low-dose intravenous immunoglobulin for children with newly diagnosed immune thrombocytopenia: protocol of a systematic review and meta-analysis
Introduction Intravenous immunoglobulin (IVIg) is a first-line treatment for children with newly diagnosed immune thrombocytopenia (ITP). However, the cost of IVIg is high. Higher doses of IVIg are associated with a more insupportable financial burden to paediatric patients’ families and may produce more adverse reactions. Whether low-dose IVIg can quickly stop bleeding and induce a durable response in treating children with newly diagnosed ITP is not yet established. Methods and analysis We will extensively search five English databases (PubMed, Embase, Web of Science, Cochrane Central Register of Controlled Trials...
Source: BMJ Open - June 29, 2023 Category: General Medicine Authors: Ren, X., Zhang, M., Zhang, X., Zhao, P., Zhai, W. Tags: Open access, Haematology (incl blood transfusion) Source Type: research

Melatonin effects on sleep quality of COVID-19 patients: a protocol for systematic review and meta-analysis of randomised controlled trials with trial sequential analysis
This study is an extraction review of data from existing studies, and thus it is unnecessary to obtain ethical approval. The results of this systematic review will be published in a peer-reviewed journal. PROSPERO registration number CRD42022359221.
Source: BMJ Open - June 22, 2023 Category: General Medicine Authors: Zhang, J. J., Sun, R., Guo, S., Zhang, H. Tags: Open access, Patient-centred medicine, COVID-19 Source Type: research

Acupuncture for gait disturbance of patients with subacute and chronic stroke: a systematic review and meta-analysis protocol
Introduction Hemiparetic gait is one of the most common sequelae of a stroke. Acupuncture has shown potential in correcting hemiplegic gait patterns and improving motor function recovery after stroke. However, controversial findings and a lack of supportive evidence on the effectiveness of acupuncture for post-stroke hemiplegia. The intelligent gait analysis system provides a new perspective for the study of hemiparetic gait. This systematic review aims to collect relevant studies and critically evaluate the efficacy and safety of acupuncture in alleviating gait disturbance of post-stroke hemiplegia based on quantified gai...
Source: BMJ Open - June 21, 2023 Category: General Medicine Authors: Sun, Z., Lin, Y.-r., Lu, M.-j., Huang, K.-y., Sun, K., Zhang, J.-b. Tags: Open access, Rehabilitation medicine Source Type: research

Acupuncture for protracted opioid abstinence syndrome: study protocol for a systematic review and meta-analysis
This study will not invade patients' personal privacy, and so ethical review is not required. The results will be disseminated in a peer-reviewed journal. PROSPERO registration number CRD42022382978.
Source: BMJ Open - June 19, 2023 Category: General Medicine Authors: Li, T., Zeng, Y. W., Zhang, F., Zhou, X., Ren, Y. Tags: Open access, Complementary medicine Source Type: research

Prevalence of post-dialysis fatigue: a systematic review and meta-analysis
Conclusions PDF is highly prevalent among HD patients.
Source: BMJ Open - June 13, 2023 Category: General Medicine Authors: Dou, J., Liu, H., Ma, Y., Wu, Y.-y., Tao, X.-b. Tags: Open access, Evidence based practice Source Type: research

Ciprofol versus propofol for sedation in gastrointestinal endoscopy: protocol for a systematic review and meta-analysis
Introduction Painless gastrointestinal endoscopy is being increasingly practised in the clinical field. The management and choice of sedation are important during the endoscopy procedure to reduce patient discomfort and facilitate high disease detection rates. Ciprofol is principally an agonist of the -aminobutyric acid type A receptor; it comprises the active ingredient HSK3486, which is similar to the currently used intravenous anaesthetic propofol in clinical practice. A systematic review and meta-analysis comparing ciprofol and propofol will be conducted to assess their efficacy and safety during endoscopy. Before star...
Source: BMJ Open - May 31, 2023 Category: General Medicine Authors: Qin, X., Lu, X., Tang, L., Wang, C., Xue, J. Tags: Open access, Anaesthesia Source Type: research

Efficacy and safety of acupuncture for post-COVID-19 depression: a protocol for systematic review and meta-analysis
Introduction Post-COVID-19 depression (PCD) is a possible sequela of COVID-19. Some doctors have used acupuncture to treat PCD, but no systematic review or meta-analysis has yet evaluated its efficacy and safety for the treatment of PCD. The aim of this systematic review is to assess the efficacy and safety of acupuncture therapy for PCD. Methods and analysis Two reviewers will independently search the Cochrane Central Register of Controlled Trials (CENTRAL), Medline (PubMed), Excerpt Medica Database (EMBASE), China National Knowledge Infrastructure (CNKI), Chinese Biomedical Literature Database (CBM), Chinese Scientific ...
Source: BMJ Open - May 11, 2023 Category: General Medicine Authors: Li, B., Liu, H., Luo, X., Liu, Y., Pan, J., Yang, M., Tian, H., Hu, C., Feng, Y., Li, C. Tags: Open access, Public health, COVID-19 Source Type: research

Value of retrograde pulmonary vein perfusion combined with pulmonary artery thrombectomy in acute pulmonary embolism: a protocol for a systematic review and meta-analysis
Introduction Acute pulmonary embolism is a serious cardiovascular disease with high mortality. Surgery is an important therapeutic means. The traditional surgical method is pulmonary artery embolectomy with cardiopulmonary bypass, but there is a certain recurrence rate after surgery. Some scholars use retrograde pulmonary vein perfusion as an adjunct to conventional pulmonary artery embolectomy. However, whether this method can be used safely for acute pulmonary embolism and its long-term effects remains unclear. Therefore, we plan to conduct a systematic review and meta-analysis to investigate whether retrograde pulmonary...
Source: BMJ Open - May 5, 2023 Category: General Medicine Authors: Xiang, J., He, L., Peng, T., Liang, W., Wei, S. Tags: Open access, Surgery Source Type: research