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Total 33 results found since Jan 2013.

Improving Senescent Wound Healing With Local and Systemic Therapies
The population is aging, and the prevalence of chronic wounds is increasing. Because neovascularization is essential for tissue repair and both local and systemic factors affect new blood vessel formation, we hypothesize that altering either pathway would reciprocally enhance wound healing in the aged. To test this hypothesis, p53 was locally suppressed and endothelial progenitor cells (EPCs) were systemically mobilized in a murine model of senescent wound healing. Bilateral 6-mm full-thickness stented wounds were made on the dorsum of Zmpste24−/− mice. Animals received weekly topical p53 small interfering RNA (siRNA)...
Source: Annals of Plastic Surgery - June 13, 2018 Category: Cosmetic Surgery Tags: Transplantation Surgery and Research Source Type: research

Polarization of THP-1-Derived Macrophage by Magnesium and MAGT1 Inhibition in Wound Healing
Conclusion Mg2+ can help to end the delay in wound healing caused by persistent inflammation in the early stages.PMID:37564721 | PMC:PMC10411119 | DOI:10.1055/s-0043-1770114
Source: Archives of Plastic Surgery - August 11, 2023 Category: Cosmetic Surgery Authors: Mun Ho Oh JaeHyuk Jang Jong Hun Lee Source Type: research