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Specialty: Reproduction Medicine
Therapy: Gene Therapy

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Total 1 results found since Jan 2013.

Modulating circulating sFlt1 in an animal model of preeclampsia using PAMAM nanoparticles for siRNA delivery
Excessive circulating sFlt1 plays a major role in the pathogenesis of preeclampsia (PE). Using RNAi to silence sFlt1 may be a therapy for treating PE. Because of the rapid degradation of siRNA, gene therapy in vivo remains limited. Poly-amidoamine (PAMAM) has been demonstrated to be an excellent nanocarrier for siRNA delivery with no discernible toxicity.
Source: Placenta - August 1, 2017 Category: Reproduction Medicine Authors: Jun Yu, Jing Jia, Xijiao Guo, Ruibao Chen, Ling Feng Source Type: research