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EP.17Vaccination as possible trigger of anti-SRP mediated necrotizing myopathy - a case report
Immunomediated necrotizing myopathy (IMNM) belongs to a heterogeneous group of inflammatory myopathies caused by myositis-specific autoantibodies including anti –3-hydroxy-3- methylglutaryl-coenzyme A (anti-HMGCR) and anti–single recognition particle (anti-SRP). IMNM anti-SRP typically presents with proximal weakness, myalgia, elevated CK and necrosis with absence of inflammation on muscle biopsy. Objective: to describe a case of IMNM anti-SRP positive after vaccination. A 42-year-old female complained of myalgia and muscle weakness affecting the neck and shoulder girdle 2 weeks after vaccination for Yellow fever, Teta...
Source: Neuromuscular Disorders - September 30, 2019 Category: Neurology Authors: J. Cavalcanti, W. Lima, K. Turke, L. Silva, A. Carvalho Source Type: research