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Clinical Characteristics of Myositis Associated with Graft-Versus-Host Disease
AbstractPurpose of ReviewRecipients of allogeneic hematopoietic stem cell transplantation (HSCT) are at increased risk for inflammatory myositis; histological subsets reported include dermatomyositis, necrotising myopathy and chronic graft-versus-host disease (cGVHD) –related myositis. Though corticosteroids and various immunosuppressive therapies have been used, there is a lack of consensus guidelines dictating therapy.Recent FindingsRecent evidence suggests the fascia as a preferential target in cGVHD myositis, with conditioning regimens promoting fascial microtrauma. Positron emission tomography (PET) can be a useful ...
Source: Current Rheumatology Reports - April 24, 2021 Category: Rheumatology Source Type: research

PET Scan: Nuclear Medicine Imaging in Myositis
AbstractPurpose of ReviewPositron emission tomography (PET) combined with computed tomography (CT) has proven useful as a cancer screening technique in patients with inflammatory myopathy, mainly dermatomyositis. In this review, we focus on advances in this direction and other potential applications of PET/CT in patients with inflammatory myopathy.Recent FindingsCancer screening by PET/CT seems suitable and cost-effective in patients with myositis. It has also shown value as a hybrid technique for diagnosing myositis versus controls and could be of interest for differentiating between polymyositis and sporadic inclusion bo...
Source: Current Rheumatology Reports - November 20, 2019 Category: Rheumatology Source Type: research

Diagnostic Imaging of Inflammatory Myopathies: New Concepts and a Radiological Approach
AbstractPurpose of ReviewThe purpose of this review article is to highlight the current role of diagnostic imaging in the assessment of inflammatory myopathies.Recent FindingsRecent research demonstrates that imaging plays an important role in evaluating patients with symptoms of an inflammatory myopathy. In general, MRI is the pivotal imaging modality for assessing inflammatory myopathies, revealing precise anatomic details because of changes in the signal intensity of the muscles. Whole-body MR imaging has become increasingly important over the last several years. US is also a valuable imaging modality for scanning muscl...
Source: Current Rheumatology Reports - February 14, 2019 Category: Rheumatology Source Type: research