Filtered By:
Source: Journal of Molecular Medicine
Nutrition: Diets
This page shows you your search results in order of relevance.
Order by Relevance | Date
Total 2 results found since Jan 2013.
High-fat diet consumption reduces hepatic folate transporter expression via nuclear respiratory factor-1
AbstractFolate is an essential micronutrient for biological function. The liver, a primary organ for folate metabolism and storage, plays an important role in folate homeostasis. Proton-coupled folate transporter (PCFT) and reduced folate carrier (RFC) are the major folate transporters responsible for folate uptake at basolateral membrane of hepatocytes. Low serum folate levels are frequently associated with obesity. We investigated the mechanism that regulated folate status in a mouse model with diet-induced obesity. Mice (C57BL/6J) were fed a high-fat diet (60% kcal fat) for 8 weeks. Mice displayed increased hepatic li...
Source: Journal of Molecular Medicine - September 4, 2018 Category: Molecular Biology Source Type: research
