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miR-582-5p inhibits invasion and migration of salivary adenoid cystic carcinoma cells by targeting FOXC1
ConclusionsmiR-582-5p could suppress effect on the process of invasion and migration in SACC cell lines, and this could occur through its target gene FOXC1.
Source: Japanese Journal of Clinical Oncology - June 7, 2017 Category: Cancer & Oncology Source Type: research

Impact of O6-methylguanine-DNA methyltransferase expression on the drug resistance of clear cell renal cell carcinoma
Conclusions The overexpression of O6-methylguanine-deoxyribonucleic acid methyltransferase contributes to resistance of clear cell renal cell carcinoma to standard chemotherapy. Our results have significance for understanding a new pathway of the development of drug resistance of clear cell renal cell carcinoma.
Source: Japanese Journal of Clinical Oncology - August 26, 2015 Category: Cancer & Oncology Authors: Ge, N., Guo, L., Zhang, J., Lin, Z., Li, Y., Liu, Y., Kong, F., Fang, X., Zhao, S. Tags: Urology, Original Articles Source Type: research

miR-128 modulates chemosensitivity and invasion of prostate cancer cells through targeting ZEB1
Conclusions miR-128 functions as a potential cancer suppressor in prostate cancer progression and rational therapeutic strategies for prostate cancer would be developed based on miR-128/zinc-finger E-box-binding homeobox 1 axis.
Source: Japanese Journal of Clinical Oncology - April 28, 2015 Category: Cancer & Oncology Authors: Sun, X., Li, Y., Yu, J., Pei, H., Luo, P., Zhang, J. Tags: Urology, Original Articles Source Type: research

Downregulated Expression of the Cyclase-associated Protein 1 (CAP1) Reduces Migration in Esophageal Squamous Cell Carcinoma
Conclusions These findings suggest that cyclase-associated protein 1 is involved in the metastasis of esophageal squamous cell carcinoma, and that elevated levels of cyclase-associated protein 1 expression may indicate a poor prognosis for patients with esophageal squamous cell carcinoma.
Source: Japanese Journal of Clinical Oncology - August 29, 2013 Category: Cancer & Oncology Authors: Li, M., Yang, X., Shi, H., Ren, H., Chen, X., Zhang, S., Zhu, J., Zhang, J. Tags: Basic Research, Original Articles Source Type: research