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In vivo comparison of the degradation and osteointegration properties of micro-arc oxidation-coated Mg-Sr and Mg-Ca alloy scaffolds
Biomed Mater Eng. 2021 Nov 2. doi: 10.3233/BME-211300. Online ahead of print.ABSTRACTBACKGROUND: Magnesium (Mg) alloy have biodegradation and mechanical properties that are similar to those of human bone, making it a promising candidate material for inclusion in implantable medical devices.OBJECTIVE: The osteointegration effect of Mg alloy scaffolds with different corrosion rates were studied and evaluated in large bone defect models.METHOD: Mg-Sr and Mg-Ca alloy scaffolds with a 20-μm Micro-arc oxidation (MAO) coating were used to repair critical bone defects for subsequent assessment of each alloy's degradation and oste...
Source: Bio-Medical Materials and Engineering - November 8, 2021 Category: Materials Science Authors: Hongyu Sun Yuefei Wang Chu Sun Haiming Yu Zheng Xi Na Liu Nan Zhang Source Type: research