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TrkB is necessary for male copulatory behavior in the Syrian Hamster (Mesocricetus auratus).
Abstract The magnocellular medial preoptic nucleus (MPN mag), a subdivision of the medial preoptic area (MPOA), plays a critical role in the regulation of copulation in the Syrian hamster; in part by mediating the effects of gonadal steroids. For example, ablation of the MPN mag eliminates mating and testosterone placed in the MPN mag restores mating in castrated males. Testosterone treatment enhances synaptic density and dendritic spines in the MPN mag. Thus, copulatory behaviors are correlated with increases in synaptic morphology in the MPN mag. As brain derived neurotrophic factor (BDNF) and its receptor, tyro...
Source: Hormones and Behavior - October 29, 2017 Category: Endocrinology Authors: Brague JC, Zinn C, Granot D, Feathers CT, Swann JM Tags: Horm Behav Source Type: research