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Stroke rehabilitation in China: a systematic review and meta‐analysis
ConclusionThese data provide some evidence that rehabilitation poststroke is more effective than no rehabilitation, improving activities of daily living and reducing disability. Although results are limited by low reporting quality and study heterogeneity, conducting research in countries in which rehabilitation is not standard care provides an opportunity to advance our understanding and should be encouraged.
Source: International Journal of Stroke - April 29, 2013 Category: Neurology Authors: Wen Wen Zhang, Sally Speare, Leonid Churilov, Matthew Thuy, Geoffrey Donnan, Julie Bernhardt Tags: Systematic Review Source Type: research

Functional connectivity magnetic resonance imaging in stroke: an evidence‐based clinical review
Stroke is a common condition that may lead to various degrees of neurological deficit and long‐term disability. It has become increasingly recognized that cortical reorganization of neuronal networks plays a significant role in regaining function following a focal brain injury. However, the mechanisms involved in this process are still not fully understood. Resting‐state functional connectivity magnetic resonance imaging is a rapidly evolving scanning technique that has the potential to shed light into this neuronal rearrangement. A better understanding of the underlying neurological pathways may contribute to the deve...
Source: International Journal of Stroke - March 19, 2013 Category: Neurology Authors: Ourania Varsou, Mary Joan Macleod, Christian Schwarzbauer Tags: Review Source Type: research

Acute middle cerebral artery occlusion: reappraisal of the role of endovascular revascularization
Intravenous tissue plasminogen activator was the first successful stroke therapy in acute ischaemic stroke, after innumerable failed attempts at neuroprotection and neurorestoration. However, intravenous tissue type plasminogen activator has been shown to be effective in recanalizing middle cerebral artery occlusions in only about one‐third of cases. The natural history of untreated acute middle cerebral artery occlusion is poor, leading to long‐term disability in >70% and mortality in 20%. Recanalization alone is not the name of the game. Only timely, very rapid recanalization, achieved within minutes or at most a ...
Source: International Journal of Stroke - January 21, 2013 Category: Neurology Authors: José E. Cohen Tags: Leading opinion Source Type: research

The disability adjusted life years due to stroke in South Africa in 2008
ConclusionsThis study provides information on prevalence, incidence and disease burden of stroke at the national level in South Africa. The results of this analysis will enable further work on priority setting and health service planning for primary and secondary prevention of stroke in South Africa.
Source: International Journal of Stroke - January 7, 2013 Category: Neurology Authors: Melanie Y. Bertram, Judith Katzenellenbogen, Theo Vos, Debbie Bradshaw, Karen J. Hofman Tags: Research Source Type: research

Leucocyte count in young adults with first‐ever ischaemic stroke: associated factors and association on prognosis
ConclusionsAmong young stroke patients, high leucocyte count was a common finding. It was associated with vascular disease and its risk factors as well as severity of stroke, but it was also independently associated with unfavourable three‐month outcome in these patients. There was no association with the long‐term outcome.
Source: International Journal of Stroke - January 1, 2013 Category: Neurology Authors: Terttu Heikinheimo, Jukka Putaala, Elena Haapaniemi, Markku Kaste, Turgut Tatlisumak Tags: Research Source Type: research

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