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Effect of addition of clopidogrel to aspirin on subdural hematoma: meta‐analysis of randomized clinical trials
ConclusionsThe absolute rate of subdural hematoma during dual antiplatelet therapy is low, averaging 1·1 per 1000 patient‐years. Chronic treatment with clopidogrel plus aspirin significantly increases the risk of subdural hematoma compared with aspirin alone.
Source: International Journal of Stroke - December 1, 2014 Category: Neurology Authors: Majid F. Bakheet, Lesly A. Pearce, Robert G. Hart Tags: Research Source Type: research

Rationale and design of Triple AXEL: trial for early anticoagulation in acute ischemic stroke patients with nonvalvular atrial fibrillation
DiscussionThe results of this proof‐of‐concept trial will guide go/no‐go decision to a large phase 3 confirmatory trial.
Source: International Journal of Stroke - October 26, 2014 Category: Neurology Authors: Keun‐Sik Hong, Yun Jung Choi, Sun U. Kwon, Tags: Protocols Source Type: research

Types of stroke recurrence in patients with ischemic stroke: A substudy from the PRoFESS trial
ConclusionsRisk predictors for stroke recurrence and for brain hemorrhage differ by index ischemic stroke subtype, information that is important when initiating secondary prevention therapy.
Source: International Journal of Stroke - October 22, 2013 Category: Neurology Authors: Danilo Toni, Emanuele Di Angelantonio, Maria Teresa Di Mascio, Richard Vinisko, Philip MW Bath, Tags: Research Source Type: research

Outcomes for people with atrial fibrillation in an Australian national audit of stroke care
ConclusionsHospital processes of care can influence outcomes in stroke patients with atrial fibrillation. The greater in‐hospital mortality experienced by stroke patients with atrial fibrillation may be attenuated by admission to a stroke unit, and for ischemic stroke, early administration of aspirin.
Source: International Journal of Stroke - July 9, 2013 Category: Neurology Authors: Nadine Andrew, Monique Kilkenny, Dawn Harris, Chris Price, Dominique A. Cadilhac Tags: Research Source Type: research