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Source: Journal of Biological Chemistry
Condition: Atrial Fibrillation
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Total 2 results found since Jan 2013.
Rac1 GTPase regulates 11{beta} hydroxysteroid dehydrogenase type 2 and fibrotic remodeling Molecular Bases of Disease
In conclusion, Rac1 GTPase regulates 11β-HSD2 expression, MR activation, and MR-mediated pro-fibrotic signaling.
Source: Journal of Biological Chemistry - May 5, 2017 Category: Chemistry Authors: Daniel Lavall, Pia Schuster, Nadine Jacobs, Andrey Kazakov, Michael Bohm, Ulrich Laufs Tags: Signal Transduction Source Type: research
F-box protein-32 down-regulates small-conductance calcium-activated potassium channel 2 in diabetic mouse atria Molecular Bases of Disease
In conclusion, DM-induced SK2 channel down-regulation appears to be due to an FBXO-32-dependent increase in UPS-mediated SK2 protein degradation.
Source: Journal of Biological Chemistry - March 14, 2019 Category: Chemistry Authors: Tian-You Ling, Fu Yi, Tong Lu, Xiao-Li Wang, Xiaojing Sun, Monte S. Willis, Li-Qun Wu, Win-Kuang Shen, John P. Adelman, Hon-Chi Lee Tags: Molecular Bases of Disease Source Type: research
