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Source: Heart Rhythm
Condition: Arrhythmia

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Total 46 results found since Jan 2013.

Anticoagulation for Stroke Prevention in Patients With Hypertrophic Cardiomyopathy and Atrial Fibrillation: A Review
Atrial fibrillation is the most common arrhythmia in patients with hypertrophic cardiomyopathy with a prevalence and incidence of 23% and 3.1% respectively. The risk of thromboembolism is high in patients with hypertrophic cardiomyopathy regardless of the CHADS2VASC score. This review includes five observational studies that focused on prevention of thromboembolism in patients with hypertrophic cardiomyopathy and atrial fibrillation. These papers evaluated and compared outcomes between patients on either warfarin or direct oral anticoagulants.
Source: Heart Rhythm - October 2, 2020 Category: Cardiology Authors: M. Farhan Nasser, Sanjay Gandhi, Robert J. Siegel, Florian Rader Source Type: research

Connexin45 (GJC1) loss-of-function mutation contributes to familial atrial fibrillation and conduction disease
Atrial fibrillation (AF) represents the most common clinical cardiac arrhythmia and substantially increases the risk for cerebral stroke, heart failure and death. Although causative genes for AF have been identified, the genetic determinants for AF remain largely unclear.
Source: Heart Rhythm - January 8, 2021 Category: Cardiology Authors: Ruo-Gu Li, Ying-Jia Xu, Willy G. Ye, Yan-Jie Li, Honghong Chen, Xing-Biao Qiu, Yi-Qing Yang, Donglin Bai Source Type: research

Early recurrence of atrial tachyarrhythmia post-atrial fibrillation ablation: Filling in the blank
Supported by the recent results of the Catheter Ablation vs Antiarrhythmic Drug Therapy for Atrial Fibrillation (CABANA) and Early Treatment of Atrial Fibrillation for Stroke Prevention (EAST-AFNET4) trials, catheter ablation is a preferable contemporary linchpin in the treatment of symptomatic atrial fibrillation (AF).1,2 Traditionally, the efficacy with ablation has been broadly defined by either objective arrhythmic recurrence such as atrial arrhythmias of over 30 seconds in duration or subjective recurrence of symptomatic arrhythmias.
Source: Heart Rhythm - June 29, 2021 Category: Cardiology Authors: Christopher A. Groh, T. Jared Bunch Source Type: research

Early recurrence of atrial tachyarrhythmia post –atrial fibrillation ablation: Filling in the blank
Supported by the recent results of the Catheter Ablation vs Antiarrhythmic Drug Therapy for Atrial Fibrillation (CABANA) and Early Treatment of Atrial Fibrillation for Stroke Prevention (EAST-AFNET4) trials, catheter ablation is a preferable contemporary linchpin in the treatment of symptomatic atrial fibrillation (AF).1,2 Traditionally, the efficacy with ablation has been broadly defined by either objective arrhythmic recurrence such as atrial arrhythmias of over 30 seconds in duration or subjective recurrence of symptomatic arrhythmias.
Source: Heart Rhythm - June 29, 2021 Category: Cardiology Authors: Christopher A. Groh, T. Jared Bunch Tags: Editorial Commentary Source Type: research

B-po02-051 atrial arrhythmia detection using insertable cardiac monitor in patients with cryptogenic stroke: a real-word cohort study
AF can be the underlying cause of cryptogenic strokes (CS). CRYSTAL-AF demonstrated that 30% developed AF by 36 months using an insertable cardiac Monitor (ICM) in patients with CS.
Source: Heart Rhythm - July 28, 2021 Category: Cardiology Authors: Jean Jacques Noubiap, Gijo Thomas, Curtis Harper, John Leonard Fitzgerald, Kevin R. Campbell, Dennis H. Lau, Melissa E. Middeldorp, Prashanthan Sanders Source Type: research

Po-716-02 short term readmission rates and clinical outcomes of anticoagulation versus watchman device in octogenarians
Atrial Fibrillation (AF) is the most common sustained cardiac arrhythmia with prevalence increasing with age. Left atrial appendage occlusion (LAAO) with watchman device has been found to be noninferior to oral anticoagulation for long-term stroke risk reduction in patients with AF. Patients greater than 80 years of age have been underrepresented in most of these trials making application of findings challenging in this subset of patients.
Source: Heart Rhythm - April 29, 2022 Category: Cardiology Authors: Varun Victor, Mahmoud Khalil, Ahmed Mohamed, Kirolos Barssoum Source Type: research

Ce-543-04 inter-atrial block identifies patients with low cha2ds2-vasc score but high stroke risk
Beyond current methods of risk stratification, clinical studies employing machine learning methodology have demonstrated that the 12-lead ECG harbors additional prognostic information for various cardiovascular outcomes. Interatrial block (IAB) manifests as P wave duration>120 msec and is associated with thromboembolism, atrial arrhythmias, and mortality.
Source: Heart Rhythm - April 29, 2022 Category: Cardiology Authors: Joshua Lampert, Shreyas Havaldar, David Power, Marc A. Miller, Abhishek Maan, Kartikeya Menon, Emmanuel Ekanem, Jonathan Gandhi, Daniel N. Pugliese, Daniel Ross Musikantow, Mohit K. Turagam, Valentin Fuster, Srinivas R. Dukkipati, Benjamin Glicksberg, Viv Source Type: research

Po-669-06 brain metabolism in patients with atrial fibrillation: insights from a pilot fdg-pet study
Atrial Fibrillation (AF) is an independent risk factor for incident dementia. Overt stroke, microembolism and microbleeds are among the main mechanisms linking this arrhythmia and cognitive dysfunction. Cerebral hypoperfusion related to beat-to-beat blood flow variation during AF can also explain the occurrence of dementia or mild cognitive impairment, as rhythm control strategies were shown to reduce its incidence. However, data regarding brain metabolism patterns in patients with AF are still scarce.
Source: Heart Rhythm - April 29, 2022 Category: Cardiology Authors: Gabriel Targueta, Vitor Delgado, Marcelo Melo, FRANCISCO CARLOS DA COSTA DARRIEUX Source Type: research

Po-661-07 a photoplethymography-based approach to atrial fibrillation-burden estimation in high-risk patients
Atrial fibrillation (AF) is the most common arrhythmia leading to hospital admission. Its incidence is linked to increased risk of stroke, congestive heart failure, and overall mortality. AF burden is a key determinant of outcomes, but accurate quantification can be limited by the cardiac monitoring period (typically days). Alternatively, longer-term monitoring comes at higher cost and often requires an invasive approach. The introduction of reliable wrist-worn devices may improve access to long-term monitoring of AF burden.
Source: Heart Rhythm - April 29, 2022 Category: Cardiology Authors: Charles A. Athill, Yuriko Tamura, Steven Szabados, Anthony Battisti, Jeffrey Ellis, Lori Crosson, Judith C. Lenane Source Type: research

Po-661-03 use of a deep learning algorithm to predict paroxysmal atrial fibrillation based on printed electrocardiographic records acquired during sinus rhythm
Atrial fibrillation (AF) is a common type of sustained arrhythmia worldwide. Asymptomatic AF, which occurs frequently, is associated with an increased incidence of ischemic stroke, heart failure, and mortality. A large number of patients with paroxysmal atrial fibrillation (PAF) remain undiagnosed due to the absence of electrocardiographic evidence of AF (AF-ECGs). If PAF could be predicted, targeted screening could improve early detection and treatment of this condition.
Source: Heart Rhythm - April 29, 2022 Category: Cardiology Authors: Yang Zhou, Yu Chen, Deyun Zhang, Shijia Geng, Guodong Wei, Ying Tian, Shenda Hong, XINGPENG LIU Source Type: research

Po-05-141 association of interatrial block and the development of atrial fibrillation among patients with hypertrophic cardiomyopathy
Atrial fibrillation (AF) is the most common sustained arrhythmia among those with hypertrophic cardiomyopathy (HCM), affecting 1 in 5 patients. The combination of HCM and AF is associated with an increased risk of stroke, heart failure, and mortality. Interatrial block (IAB) is a distinct electrocardiographic (ECG) pattern describing conduction delay between the right and left atria through Bachmann ’s bundle. IAB has been identified as a predictor of AF across several disease states including congestive heart failure, valvular disease, and cardiac amyloidosis.
Source: Heart Rhythm - May 1, 2023 Category: Cardiology Authors: Abdullah Alissa, Nadia Bokhari, Munther K. Homoud, Ethan Rowin, Martin S. Maron, Christopher Madias Source Type: research

Po-04-144 impact of age on atrial arrhythmia outcomes after percutaneous asd closure
Atrial Septal Defects (ASD) are one of the most common congenital heart defects, and if unrepaired, increase the risk of atrial fibrillation (AF) and atrial flutter (AFL). AF/AFL are linked to an increased risk of stroke and heart failure yet, it is not clear from existing data whether percutaneous ASD closure reduces the overall burden of AF/AFL and whether AF/AFL prevalence is impacted by closure age.
Source: Heart Rhythm - May 1, 2023 Category: Cardiology Authors: Brendan Burke, Ghazaleh Goldar, Jeevanantham Rajeswaran, Alex Milinovich, Olivia McCloskey, Patricia Blazevic, Peter F. Aziz, Tara Karamlou, Mohamed Kanj, Patcharapong Suntharos, Joanna Ghobrial Source Type: research

Po-04-057 atrial fibrillation cured by pacemaker reprogramming
Atrial fibrillation (AF) is commonly detected by remote monitoring of implanted devices. A common question is whether to start anticoagulation in patients with detected AF at risk of stroke. However, the cause of AF is rarely able to be diagnosed or corrected. Repetitive non-reentrant ventriculoatrial synchrony (RNRVAS) is a pacemaker mediated arrhythmia that can occur in patients with intact ventriculoatrial (VA) conduction. Ventricular pacing with retrograde atrial activation that falls within the PVARP is followed by atrial pacing, often delivered while the atrium is refractory.
Source: Heart Rhythm - May 1, 2023 Category: Cardiology Authors: Erin E. Flatley, Edward P. Gerstenfeld Source Type: research

Po-01-108 elucidating the mechanism of atrial fibrillation in lamin a/c heart disease using human ipsc-derived atrial cardiomyocytes
Mutations in the LMNA gene, encoding the nuclear envelope proteins lamin A/C, cause cardiac arrhythmias, conduction disease, and dilated cardiomyopathy. Malignant arrhythmias such as atrial fibrillation (AF) and ventricular tachycardia are common and pose an increased risk of stroke and sudden cardiac death.
Source: Heart Rhythm - May 1, 2023 Category: Cardiology Authors: William Janes, Asia Owais, Hanna Chen, Yining Chen, Michael Hill, Dawood Darbar, Srinath Yeshwant Source Type: research

Ce-452772-3 self-pulse exam for atrial fibrillation screening: a randomized controlled trial
Atrial fibrillation (AF), the most commonly treated cardiac arrhythmia, is associated with significant morbidity including the potential for stroke. Because AF is often asymptomatic, there is growing interest in AF screening. Trials of AF screening using external monitors, smartwatches, or other personal electronic devices have shown that screening increases detection of AF. Due to the cost and low yield of screening with insufficient evidence of clinical benefit, the US Preventative Services Task Force has not recommended comprehensive screening for AF at the current time.
Source: Heart Rhythm - May 1, 2023 Category: Cardiology Authors: Benjamin Chilcutt, Taylor C. Bazemore, Tiffany Armbruster, Ari Becker, Wanting Jin, Quefeng Li, Anil K. Gehi Source Type: research