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Postoperative Complications in Patients With Hereditary Hemochromatosis Undergoing Total Joint Arthroplasty: A Matched Cohort Analysis
This study addresses a paucity in the current literature concerning the complication profile in HH patients with destructive joint arthropathy undergoing joint arthroplasty surgery.PMID:34932508 | DOI:10.5435/JAAOS-D-21-00105
Source: The Journal of the American Academy of Orthopaedic Surgeons - December 21, 2021 Category: Orthopaedics Authors: Amil R Agarwal Kevin Y Wang Amy L Xu Matthew J Best Varun Puvanesarajah Umasuthan Srikumaran Gregory J Golladay Savya C Thakkar Source Type: research

No Difference in Blood Loss and Risk of Transfusion Between Patients Treated with One or Two Doses of Intravenous Tranexamic Acid After Simultaneous Bilateral TKA
CONCLUSION: The findings of this study suggest that a single dose of intravenous TXA may be adequate to control excessive blood loss and reduce blood transfusion in simultaneous bilateral TKA. Despite its short half-life, TXA still appears to be effective in this demanding procedure without requiring prolonged plasma concentrations obtained from multiple doses. Additional high-quality studies are still needed to determine the most appropriate dosing regimen.LEVEL OF EVIDENCE: Level III, therapeutic study.PMID:35302971 | DOI:10.1097/CORR.0000000000002037
Source: Clinical Orthopaedics and Related Research - March 18, 2022 Category: Orthopaedics Authors: Jeffrey M Wilde Steven N Copp Kace A Ezzet Adam S Rosen Richard H Walker Julie C McCauley Audree S Evans William D Bugbee Source Type: research