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Splenectomy to Optimize Hemoglobin S Control in Children With Sickle Cell Anemia on Chronic Transfusion Therapy for Stroke Prevention
Chronic transfusion therapy with the goal of maintaining a hemoglobin (Hb) S
Source: Journal of Pediatric Hematology Oncology - February 21, 2019 Category: Hematology Tags: Clinical and Laboratory Observations Source Type: research

Treatment-related Correlates of Growth in Children With Sickle Cell Disease in the DISPLACE Cohort
This study investigated growth and hemolysis in children with SCD in the DISPLACE (Dissemination and Implementation of Stroke Prevention Looking at the Care Environment) cohort. The database includes 5287 children, of which, 3305 had at least 2 growth measurements over a 5-year period. Body mass index was converted to z-scores (zBMI), and 19.8%, 66.1%, 14.2% of children were classified as underweight, normal, and overweight/obese, respectively. Multivariable analysis of growth was conducted and included variables: age, sex, blood pressure, hemoglobin, reticulocyte count, treatment with chronic red cell transfusion therapy ...
Source: Journal of Pediatric Hematology Oncology - June 30, 2022 Category: Hematology Tags: Original Articles Source Type: research