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Management of stroke patients submitted to botulinum toxin type A therapy: a Delphi survey of an Italian expert panel of specialist injectors.
CONCLUSIONS:The results of this national survey confirm that clinical experts on the use of BTX- -A therapy for spasticity after stroke agree on the need to initiate rehabilitation treatment immediately after BTX--A injection: muscle stretching exercises, eventually combined with neuromuscular electrical stimulation, may enhance the effect of BTX--A therapy. Outcome after BTX--A therapy should be assessed at repeated follow--up visits. PMID: 24963604 [PubMed - as supplied by publisher]
Source: European Journal of Physical and Rehabilitation Medicine - June 19, 2014 Category: Rehabilitation Authors: Franceschini M, Iocco M, Molteni F, Santamato A, Smania N Tags: Eur J Phys Rehabil Med Source Type: research

Efficacy and safety of Botulinum Toxin type A for upper limb spasticity after stroke or traumatic brain injury: a systematic review with meta-analysis and trial sequential analysis.
CONCLUSIONS: As compared with placebo, Botulinum Toxin type A injections have beneficial effects with improved muscle tone and well-tolerated treatment for patients with upper limb spasticity post stroke or traumatic brain injury. PMID: 27834471 [PubMed - as supplied by publisher]
Source: European Journal of Physical and Rehabilitation Medicine - November 10, 2016 Category: Rehabilitation Authors: Dong Y, Wu T, Hu X, Wang T Tags: Eur J Phys Rehabil Med Source Type: research

Evaluating the functional outcomes of ultrasound-guided botulinum toxin type A injections using the Euro-musculus approach for upper limb spasticity treatment in post-stroke patients; an observational study.
CONCLUSIONS: Ultrasound-guided botulinum toxin type A injection via the Euro- musculus spasticity approach is a practical and effective method for administering injections to the correct point of the correct muscle. Ultrasound-guided botulinum toxin type A injections combined with rehabilitation programmes decrease spasticity and improve the upper extremity motor functions in stroke patients. CLINICAL REHABILITATION IMPACT: This new approach for ultrasound- guided botulinum toxin type A injection is very practical and effective method for upper extremity spasticity. PMID: 29422486 [PubMed - as supplied by publisher]
Source: European Journal of Physical and Rehabilitation Medicine - February 7, 2018 Category: Rehabilitation Authors: Buyukavci R, Akturk S, Ersoy Y Tags: Eur J Phys Rehabil Med Source Type: research

Safety and efficacy of incobotulinum toxin type A (NT 201-Xeomin) for the treatment of post-stroke lower limb spasticity: a prospective open-label study.
Conclusion: BTX-A NT 201 for the treatment of post-stroke lower limb spasticity was safe and efficacious reducing muscle tone and spasms, and improving passive ankle dorsi-flexion movement. Clinical rehabilitation impact. These results confirmed the safety and effectiveness of a new type of BTX-A, with low immunogenity, useful to improve rehabilitative treatment of post-stroke lower limb spasticity. PMID: 23480980 [PubMed - as supplied by publisher]
Source: European Journal of Physical and Rehabilitation Medicine - March 13, 2013 Category: Rehabilitation Authors: Santamato A, Micello MF, Panza F, Fortunato F, Pilotto A, Giustini A, Testa A, Fiore P, Ranieri M, Spidalieri R Tags: Eur J Phys Rehabil Med Source Type: research

Combined effects of robot-assisted gait training and botulinum toxin type A effect on spastic equinus foot in patients with chronic stroke: a pilot, single blind, randomized controlled trial.
CONCLUSIONS: Our preliminary findings support the hypothesis that robot-assisted gait training does not enhance the effect of botulinum toxin type A on spastic equinus foot in patients with chronic stroke. CLINICAL REHABILITATION IMPACT: Our observations should be taken into account in daily clinical rehabilitation practice in order to develop effective treatment protocols based on the enhancement of antispastic drugs effect. PMID: 27098300 [PubMed - as supplied by publisher]
Source: European Journal of Physical and Rehabilitation Medicine - April 20, 2016 Category: Rehabilitation Authors: Picelli A, Bacciga M, Melotti C, LA Marchina E, Verzini E, Ferrari F, Pontillo A, Corradi J, Tamburin S, Saltuari L, Corradini C, Waldner A, Smania N Tags: Eur J Phys Rehabil Med Source Type: research

Use of gait parameters to predict the effectiveness of botulinum toxin injection in the spastic Rectus Femoris muscle of stroke patients with Stiff Knee Gait.
CONCLUSION: The percentage increase in peak knee flexion in swing during fast gait before injection is a useful predictor of the increase in peak knee flexion following RF BTX-A injection in chronic stroke patients with RF spasticity. PMID: 25213306 [PubMed - as supplied by publisher]
Source: European Journal of Physical and Rehabilitation Medicine - September 12, 2014 Category: Rehabilitation Authors: Roche N, Boudarham J, Hardy A, Bonnyaud C, Bensmail D Tags: Eur J Phys Rehabil Med Source Type: research

Heart rate variability (hrv) modifications in adult hemiplegic patients after botulinum toxin type a (nt-201) injection.
CONCLUSION: The use of incobotulinumtoxinA in adult patients at doses up to 12 units/kg seems to be safe regarding autonomic heart drive. CLINICAL REHABILITATION IMPACT: The use of IncobotulinumtoxinA up to 600 units could be a safe therapeutic option in spastic hemiplegic stroke survivors. PMID: 25051207 [PubMed - as supplied by publisher]
Source: European Journal of Physical and Rehabilitation Medicine - July 22, 2014 Category: Rehabilitation Authors: Invernizzi M, Carda S, Molinari C, Stagno D, Cisari C, Baricich A Tags: Eur J Phys Rehabil Med Source Type: research

A systematic review on extracorporeal shock wave therapy and botulinum toxin for spasticity treatment: a comparison on efficacy
CONCLUSIONS: A beneficial effect on spasticity was found for both treatments: evidence showed that ESWT and BoNT-A can ameliorate spasticity considering parameters such as MAS, MTS, AROM, PROM, UE-FMA, VAS and SFS in post-stroke, multiple sclerosis, and cerebral palsy patients. Further research is required to strengthen the evidence, and more suitable study protocols are highly needed.PMID:35412036 | DOI:10.23736/S1973-9087.22.07136-2
Source: European Journal of Physical and Rehabilitation Medicine - April 12, 2022 Category: Rehabilitation Authors: Emanuela E Mihai Marius N Popescu Alina N Iliescu Mihai Berteanu Source Type: research

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