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Body Mass Index and Stroke Subtype in a Young Adult Stroke Population (I12-5D)
CONCLUSIONS: In our group of young adult stroke patients, we found the highest BMI in the group with intracranial atherosclerosis. Although this group represented a small number of patients, this young adult population is at increased risk for future strokes. It is important to educate them on lifestyle modifications such as weight loss and exercise in addition to the treatment of hypertension, diabetes mellitus and hyperlipidemia.Disclosure: Dr. Youn has nothing to disclose. Dr. Aung has nothing to disclose. Dr. Afrasiabi has nothing to disclose. Dr. Clark has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Youn, J., Aung, T., Afrasiabi, M., Clark, J. Tags: Obesity and Neurological Disorders Poster Presentations Source Type: research

A Case of Multiple Recurrent Ischemic Stroke in a Patient with Cholangiocarcinoma and Initiation of Anticoagulation Therapy for Secondary Stroke Prevention (P4.342)
CONCLUSIONS: Initiation of anticoagulation therapy and the optimal medications for secondary stroke prevention in cancer associated stroke remain controversial. Further randomized prospective studies are needed to establish treatment guidelines.Disclosure: Dr. Cheng has nothing to disclose. Dr. Then has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Cheng, J. Z., Then, R. Tags: Cerebrovascular Case Reports Source Type: research

Clinical Characteristics of PFO Stroke in Pregnancy (P2.274)
CONCLUSIONS: PFO may pose unique risks compared to non-PFO related stroke in pregnancy. Novel risk factors such as May-Thurner’s anatomy, which promote venous clotting with the increase in abdominal girth are important during pregnancy. For high risk individuals (such as those with known hypercoagulable state), screening for PFO may be of clinical utility in preventing strokes. Further studies are ongoing to validate these preliminary findings. Study Supported by: None.Disclosure: Dr. Chen has nothing to disclose. Dr. Deng has nothing to disclose. Dr. Wickham has nothing to disclose. Dr. McMullin D has nothing to dis...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Chen, L., Deng, W., Wickham, T., McMullin D, D., Eng H, L., Buonanno, F., Ning, M. Tags: Cerebrovascular Disease and Interventional Neurology: PFO and Other Cardiac Disease Source Type: research

Utility of Pelvic MRV in Evaluation of Patients with Cryptogenic Stroke and PFO (P4.228)
CONCLUSIONS: Our data expands on prior study showing that pelvic MRV has the potential to identify a stroke source in patients with cryptogenic stroke, absent identifiable hypercoagulability state, and PFO.Disclosure: Dr. Osgood has nothing to disclose. Dr. Budman has nothing to disclose. Dr. Henninger has received personal compensation for activities with Brainsgate as a consultant.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Osgood, M., Budman, E., Henninger, N. Tags: Cerebrovascular Disease and Interventional Neurology: Cardiac Source Type: research

Effect of Patent Foramen Ovale (PFO) Endovascular Closure on Stroke Quality of Life (P4.229)
Conclusion: PFO stroke patients have improved quality of life after PFO closure as measured by validated quantitative anxiety and depression scales under multi-disciplinary care. Patient’s stress hormone levels were also lowered post PFO closure. These findings demonstrate the importance of a multi-disciplinary approach to stroke patient care, and individualizing care in younger stroke patients. Longer term future studies are needed to understand the effect of PFO closure vs multi-disciplinary specialized care.Study Supported by: NIH/NINDSDisclosure: Dr. K has nothing to disclose. Dr. Ning has nothing to disclose. Dr...
Source: Neurology - April 9, 2014 Category: Neurology Authors: K, F.-H., Ning, M., Deng, W., Wickham, T., Inglessis, I., Lo, E., Palacios, I., Buonanno, F. Tags: Cerebrovascular Disease and Interventional Neurology: Cardiac Source Type: research

PFO Closure for Stroke Prevention. A Brief Meta-Analysis (P2.011)
CONCLUSIONS: This meta-analysis found benefit of PFO closure with the Amplatzer PFO Occluder in reducing tissue-defined recurrent ischemic stroke, but no statistically significant benefit in reducing TIA, study-defined ischemic stroke, or all-cause death.Disclosure: Dr. Latini has nothing to disclose. Dr. Saver has received personal compensation for activities with the University of California, BrainsGate, CoAxia, ev3, Talecris, PhotoThera, Sygnis, and Stryker. Dr. Saver has received research support from the University of California, and the National Institutes of Health.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Doldan, L., Latini, M., Saver, J. Tags: Cerebrovascular Disease and Interventional Neurology I Source Type: research

Synthetic Cannabis and Acute Ischemic Stroke (P6.259)
CONCLUSIONS:These cases introduce a previously unreported association between synthetic cannabis use and ischemic stroke in young adults. Our two cases had risk factors for ischemic stroke but were otherwise young and healthy and the onset of their deficits occurred within hours after first-time exposure to synthetic cannabis. Synthetic cannabis use is an important consideration in the investigation of stroke in young adults.Disclosure: Dr. Bernson-Leung has nothing to disclose. Dr. Leung has nothing to disclose. Dr. Kumar has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Bernson-Leung, M., Leung, L., Kumar, S. Tags: Cerebrovascular Disease and Interventional Neurology: Case Reports Source Type: research

Circadian variation in patients with cryptogenic stroke and patent foramen ovale (P3.252)
Conclusions:These data suggest that strokes occur more frequently in the morning hours in patients with CS and PFO. Hypertension is significantly lower in patients with symptom onset between 0601 and 1200, which may further imply embolism as the potential mechanism of stroke in these patients. Further studies with larger datasets are required to investigate the circadian variation of PFO-attributable strokes.Disclosure: Dr. Daneshmand has nothing to disclose. Dr. Thaler has received personal compensation for activities with St. Jude Medical WL and Gore Associates as a consultant.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Daneshmand, A., Thaler, D. Tags: Cerebrovascular Disease Epidemiology Source Type: research

Ischemic stroke in a patient with Parry-Romberg syndrome (P4.064)
Conclusions:The only other reported patient with PRS and stroke was also found to have a PFO. It is possible that the elevated ANA seen in this patient correlates with propensity towards small venous clots not seen on ultrasound. This may lead to paradoxical emboli and ischemic strokes. It is important to note this potential association between PRS and ischemic stroke in young patients without other known risk factors. It would be worthwhile to treat this subset of patients with medications for secondary stroke prevention.Disclosure: Dr. Ebiana has nothing to disclose. Dr. Singh has nothing to disclose. Dr. Khosa has nothi...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Ebiana, V., Singh, S., Khosa, S., Moheb, N., Trikamji, B., Rao, N., Mishra, S. Tags: General Neurology: Vascular Neurology Source Type: research

Acute Pediatric Ischemic Stroke Management: a window for opportunity? (P4.175)
Conclusions:Pediatric stroke is a rare condition, with one of the most common causes being congenital cardiac disease. Unfortunately, we lack evidence-based guidelines to guide its management. Based upon pathophysiology, we believe children’s significant collateral circulation and outstanding plasticity may broaden the temporal window for intervention in acute stroke.Disclosure: Dr. Pace has nothing to disclose. Dr. Dorn has nothing to disclose. Dr. Kulhari has nothing to disclose. Dr. Kandregula has nothing to disclose. Dr. Bozorgi has nothing to disclose. Dr. Alrajeh has nothing to disclose. Dr. Manjila has nothing...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Pace, J., Dorn, E., Kulhari, A., Kandregula, K., Bozorgi, A., Alrajeh, M., Manjila, S., Ramos-Estebanez, C. Tags: Child Neurology II Source Type: research

Value of Eye Movement Exam in Aiding Precise Localization in Stroke (P1.016)
We present an unusual presentation of midbrain stroke presenting with bilateral ptosis in an African American male with vascular risk factors and concurrent use of bevacizumab. This case illustrates how detailed knowledge of anatomy and detailed neurologic exam remain valuable tools for localizing and diagnosing subtle presentations of common neurologic disease. Case description: A 69 year-old African American man with vascular risk factors including hypertension, hyperlipidemia and poorly controlled diabetes experienced sudden onset horizontal diplopia associated with fatigue. The patient presented to the Emergency Depart...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Khandker, N., Schmerler, D., Mahajan, S., Serra, A., Strbian, D. Tags: Cerebrovascular Disease and Interventional Neurology I ePosters Source Type: research

Analysis of Inpatient Thrombophilia Testing for Adults with an Ischemic Stroke or Transient Ischemic Attack and its Impact on Clinical Management (P1.123)
Conclusions: Inpatient thrombophilia testing did not affect management in the vast majority of patients with an ischemic stroke or TIA despite a positive test result. Therefore, by avoiding inpatient testing, healthcare costs may be reduced without affecting patient care.Disclosure: Dr. Gavva has nothing to disclose. Dr. Alberts has received personal compensation for activities with AGA medical, AstraZeneca, Bayer, Pfizer, Bistol-Myers-Squibb, Boehringer Ingelheim, diaDexus, Genentech, KOS, Medicine Company, PDL biopharma, Pfizer, Photothera, Sanofi. Dr. Johnson has nothing to disclose. Dr. Sarode has received personal com...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Gavva, C., Alberts, M., Johnson, M., Sarode, R. Tags: Cerebrovascular Disease: Epidemiology Source Type: research

Cryptogenic stroke and patent foramen ovale: The role of Valsalva maneuver and prolonged immobility (P3.079)
Conclusions:Our study provides an estimated prevalence of Valsalva maneuver and prolonged immobility in patients with CS and PFO. The analysis suggests a possible association between high RoPE score and prolonged immobility, in patients with Valsalva at the time of symptom onset. Further investigations with larger sample sizes are required to reach more precise estimates for the associations examined.Disclosure: Dr. Daneshmand has nothing to disclose. Dr. Koulouridis has nothing to disclose. Dr. Thaler has received personal compensation for activities with St. Jude Medical WL and Gore Associates as a consultant.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Daneshmand, A., Koulouridis, I., Thaler, D. Tags: Cerebrovascular Disease and Interventional Neurology ePoster Session Source Type: research

Long-term Risk of Complications after Percutaneous Transcatheter Closure of Patent Foramen Ovale (S51.003)
Conclusions:Approximately 1 in 6 patients who undergo percutaneous transcatheter closure of PFO after stroke or transient ischemic attack experience a serious complication or death within 5 years.Study Supported by:Dr. Gialdini is supported by the Feil Family Foundation.Dr. Navi is supported by NIH grant K23NS091395 and the Florence Gould Endowment for Discovery in Stroke.Dr. Iadecola is supported by NIH grants R37NS089323-02, R01NS034179-21, R01NS037853-19, and R01 NS073666-04.Dr. Kamel is supported by NIH grants K23NS082367 and R01NS097443 as well as the Michael Goldberg Research Fund.Disclosure: Dr. Merkler has nothing ...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Merkler, A., Gialdini, G., Yaghi, S., Okin, P., Iadecola, C., Navi, B., Kamel, H. Tags: Cerebrovascular Disease and Interventional Neurology: Stroke Prevention and Translation Source Type: research

"Fou Rire Prodromique" as the Presentation of a Left Frontal Ischemic Stroke (P02.040)
CONCLUSIONS: Frontal lobe involvement affecting the Broca's area, as we described in our case, has only been described once. We conclude that the patient's laughter attack was the initial manifestation of the stroke suggesting that an acute infarct of Broca's area is capable of producing this unusual clinical presentation.Disclosure: Dr. Rosales has nothing to disclose. Dr. Garcia-Gracia has nothing to disclose. Dr. Salgado has received personal compensation in an editorial capacity from Belvoir Media Group as Consulting Editor of A Special Report published by the editors of Heart Advisor Cleveland Clinic STROKE: Advances ...
Source: Neurology - February 14, 2013 Category: Neurology Authors: Rosales, D., Garcia-Gracia, C., Salgado, E. Tags: P02 Cerebrovascular Disease II Source Type: research

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