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Source: Heart
Condition: Hypertension

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Total 72 results found since Jan 2013.

The unnatural history of an atrial septal defect: Longitudinal 35 year follow up after surgical closure at young age
Conclusions Very long-term outcome after surgical ASD closure in childhood shows good survival and low morbidity. Early surgical closure prevents pulmonary hypertension and reduces the occurrence of supraventricular arrhythmias. Early postoperative arrhythmias are predictive for the need for pacemaker implantation during early follow-up, but the rate of late pacemaker implantation remains low. Although RVEF was unexpectedly found to be decreased in one-third of patients, the functional status remains excellent.
Source: Heart - August 15, 2013 Category: Cardiology Authors: Cuypers, J. A. A. E., Opic, P., Menting, M. E., Utens, E. M. W. J., Witsenburg, M., Helbing, W. A., van den Bosch, A. E., Ouhlous, M., van Domburg, R. T., Meijboom, F. J., Bogers, A. J. J. C., Roos-Hesselink, J. W. Tags: Congenital Heart Disease, Congenital heart disease, Drugs: cardiovascular system, Echocardiography, Hypertension, Clinical diagnostic tests, Epidemiology Source Type: research

Recent advances in the epidemiology, outcome, and prevention of myocardial infarction and stroke in sub-Saharan Africa
The early part of the new millennium witnessed reports of a growing burden of cardiovascular disease in Sub-Saharan Africa (SSA). However the contribution of ischemic heart disease and stroke to this increasing burden relative to that caused by hypertensive heart disease, cardiomyopathy and rheumatic heart disease was not clear. Over the last decade, data from the continent has begun to clarify this issue and suggests three main points. The burden of ischemic heart disease relative to other causes of heart disease remains low particularly in the black Africans majority. Stroke caused predominantly by hypertension is now a ...
Source: Heart - August 2, 2013 Category: Cardiology Authors: Ntsekhe, M., Damasceno, A. Tags: Drugs: cardiovascular system, Hypertension, Acute coronary syndromes, Epidemiology Global burden of cardiovascular disease Source Type: research

Ethnicity and stroke risk in patients with atrial fibrillation
Conclusions Despite a reduced prevalence of AF among South Asian patients, their risk of stroke is higher than for white patients or black African/Caribbean patients in association with diabetes, cardiovascular disease, and hypertension. Under-prescription of anticoagulation persists in all ethnic groups, a deficit most pronounced in the elderly. Use of the CHA2DS2VASc score would enhance optimal management in primary care.
Source: Heart - July 5, 2013 Category: Cardiology Authors: Mathur, R., Pollara, E., Hull, S., Schofield, P., Ashworth, M., Robson, J. Tags: Drugs: cardiovascular system, Hypertension, Epidemiology Heart rhythm disorders Source Type: research

The 10 'Best Buys' to combat heart disease, diabetes and stroke in Africa
The Economist has branded Africa as ‘the world's fastest growing continent’.1 The economy in many African countries is growing at a rate that is higher than that of European countries. HIV infection is coming under control and life expectancy is increasing as a result of widespread use of antiretroviral therapy.2 The rising economic prosperity and improving health status has been associated with what can be described as a renaissance in cardiovascular medicine that is characterised by the revival of pan-African professional organisations, such as the Pan African Society of Cardiology (PASCAR) and the creation o...
Source: Heart - June 26, 2013 Category: Cardiology Authors: Mayosi, B. M. Tags: Drugs: cardiovascular system, Hypertension, Acute coronary syndromes, Epidemiology Editorials Source Type: research

Development and validation of a prediction rule for recurrent vascular events based on a cohort study of patients with arterial disease: the SMART risk score
Conclusions Patients at high risk for recurrent vascular events can be identified based on readily available clinical characteristics.
Source: Heart - May 13, 2013 Category: Cardiology Authors: Dorresteijn, J. A. N., Visseren, F. L. J., Wassink, A. M. J., Gondrie, M. J. A., Steyerberg, E. W., Ridker, P. M., Cook, N. R., van der Graaf, Y., on behalf of the SMART Study Group, Algra, Grobbee, Rutten, Moll, Kappelle, Mali, Doevendans Tags: Drugs: cardiovascular system, Hypertension, Acute coronary syndromes, Clinical diagnostic tests, Epidemiology, Tobacco use Prognosis research Source Type: research

The role of uric acid in the pathogenesis of human cardiovascular disease
Hyperuricaemia is common in subjects with cardiovascular disease, but is not commonly considered a true risk factor. Recent studies suggest that uric acid is biologically active and can stimulate oxidative stress, endothelial dysfunction, inflammation and vasoconstriction. Epidemiological studies have found that uric acid can independently predict the development of hypertension, as well as stroke and heart failure. Experimentally raising uric acid in animals increases blood pressure, and pilot studies suggest that lowering uric acid in humans can reduce blood pressure in hypertensive individuals. Uric acid may also have e...
Source: Heart - May 1, 2013 Category: Cardiology Authors: Kanbay, M., Segal, M., Afsar, B., Kang, D.-H., Rodriguez-Iturbe, B., Johnson, R. J. Tags: Reviews Source Type: research

Incidence, cardiovascular complications and mortality of hypertension by sex and ethnicity
Conclusions South Asian patients had higher rates of hypertension compared to the other ethnic groups. South Asian and Chinese patients had a lower risk of death and developing cardiovascular outcomes compared to whites. Women with hypertension have a better prognosis than men regardless of ethnicity.
Source: Heart - April 18, 2013 Category: Cardiology Authors: Quan, H., Chen, G., Walker, R. L., Wielgosz, A., Dai, S., Tu, K., Campbell, N. R. C., Hemmelgarn, B. R., Hill, M. D., Johansen, H., McAlister, F. A., Khan, N., for Hypertension Outcome and Surveillance Team Tags: Hypertension, Editor's choice, Drugs: cardiovascular system, Hypertension, Acute coronary syndromes, Epidemiology Source Type: research

Methods of accelerated atherosclerosis in diabetic patients
This article will focus on the effect of diabetes on the initiation and progression of arterial occlusive disease, preceded by a short outline of the enormous impact of this issue from a societal-economic perspective. Diabetes, a major healthcare issue The prevalence and associated costs of diabetes are expected to increase significantly. There are currently over 240...
Source: Heart - April 18, 2013 Category: Cardiology Authors: Pasterkamp, G. Tags: Diabetic heart disease, Health policy, Education in Heart, Drugs: cardiovascular system, Hypertension, Acute coronary syndromes, Stable coronary heart disease, Epidemiology, Diabetes, Metabolic disorders Source Type: research

Blood pressure targets in patients with coronary artery disease: observations from traditional and Bayesian random effects meta-analysis of randomised trials
Conclusions The present body of evidence suggests that in patients with CAD, intensive systolic BP control to ≤135 mm Hg and possibly to ≤130 mm Hg is associated with a modest reduction in stroke and heart failure but at the expense of hypotension. Lower was better, although not consistently so for myocardial infarction, stroke, heart failure and perhaps angina. Further trials are needed to prove these findings.
Source: Heart - April 5, 2013 Category: Cardiology Authors: Bangalore, S., Kumar, S., Volodarskiy, A., Messerli, F. H. Tags: Drugs: cardiovascular system, Hypertension, Acute coronary syndromes, Stable coronary heart disease, Epidemiology Systematic review Source Type: research

Risk assessment in hypertrophic cardiomyopathy: contemporary guidelines hampered by insufficient evidence
If it were not for the great variability among individuals, medicine might as well be a science and not an art. (Sir William Osler, 1892) The sudden unexpected death of an individual at any age has a profound effect on the family and the wider community and this is particularly significant when it affects a young person. Hypertrophic cardiomyopathy remains one of the common causes of sudden cardiac death (SCD) in young individuals.1 In a cohort of 744 patients with hypertrophic cardiomyopathy from the USA and Italy, where 86 (12%) died over an 8 (SD±7) year period of follow-up, three main modes of death were identif...
Source: Heart - March 19, 2013 Category: Cardiology Authors: McKeown, P. P., Muir, A. R. Tags: Open access, Hypertrophic cardiomyopathy, Drugs: cardiovascular system, Hypertension Editorials Source Type: research

Trends in cardiovascular mortality and hospitalisations, and potential contribution of inhospital case-fatality rates to changes in national mortality in the Czech Republic 1994-2009
Conclusions During the study period, the overall CVD hospitalisation rates remained high but inhospital CFR declined considerably. The improved case-fatality seems to have made a substantial contribution to the decline in the national CVD mortality, particularly for AMI and stroke.
Source: Heart - February 18, 2013 Category: Cardiology Authors: Davidkovova, H., Kysely, J., Kriz, B., Vojtisek, P., Bobak, M. Tags: Health policy, Drugs: cardiovascular system, Hypertension, Acute coronary syndromes, Stable coronary heart disease, Epidemiology Source Type: research

Exercise-induced torsional dyssynchrony relates to impaired functional capacity in patients with heart failure and normal ejection fraction
Conclusions HFNEF involves exercise-induced torsional dyssynchrony in systole and diastole, which relates to LV hypertrophy as well as exercise capacity.
Source: Heart - January 25, 2013 Category: Cardiology Authors: Tan, Y. T., Wenzelburger, F. W., Sanderson, J. E., Leyva, F. Tags: Heart failure, Drugs: cardiovascular system, Echocardiography, Hypertension, Clinical diagnostic tests Source Type: research