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Condition: Hypertension
Management: Electronic Health Records (EHR)
Countries: Germany Health
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GWAS of longitudinal trajectories at biobank scale
Biobanks linked to massive, longitudinal electronic health record (EHR) data make numerous new genetic research questions feasible. One among these is the study of biomarker trajectories. For example, high blood pressure measurements over visits strongly predict stroke onset, and consistently high fasting glucose and Hb1Ac levels define diabetes. Recent research reveals that not only the mean level of biomarker trajectories but also their fluctuations, or within-subject (WS) variability, are risk factors for many diseases.
Source: The American Journal of Human Genetics - February 22, 2022 Category: Genetics & Stem Cells Authors: Seyoon Ko, Christopher A. German, Aubrey Jensen, Judong Shen, Anran Wang, Devan V. Mehrotra, Yan V. Sun, Janet S. Sinsheimer, Hua Zhou, Jin J. Zhou Tags: Article Source Type: research
