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Apoptotic effect of dibenzylideneacetone on oral cancer cells via modulation of specificity protein 1 and Bax
ConclusionThese findings suggest that DBA may be a potential anticancer drug candidate to induce apoptosis through down‐regulation of Sp1 in human oral cancer.
Source: Oral Diseases - January 11, 2013 Category: ENT & OMF Authors: H‐J Yu, J‐A Shin, J‐S Nam, B S Kang, S‐D Cho Tags: Original Article Source Type: research

The in vitro apoptotic effects of A248 and A1659, newly synthetic HDAC inhibitors in oral cancer cells
ConclusionThese results suggest that A248 and A1659, two new HDAC inhibitors may be attractive therapeutic drug candidates for targeting Sp1 in human oral cancer cells.This article is protected by copyright. All rights reserved.
Source: Oral Diseases - July 1, 2013 Category: ENT & OMF Authors: Ji‐Ae Shin, Gyoonhee Han, Song‐Kyu Park, Kiho Lee, Hyun‐Jung Kim, Sung‐Dae Cho, Hwan Mook Kim Tags: Original Article Source Type: research

The in vitro apoptotic effects of A248 and A1659, newly synthetic histone deacetylase inhibitors in oral cancer cells
ConclusionThese results suggest that A248 and A1659, two new HDAC inhibitors, may be attractive therapeutic drug candidates for targeting Sp1 in human oral cancer cells.
Source: Oral Diseases - July 14, 2013 Category: ENT & OMF Authors: J‐A Shin, G Han, S‐K Park, K Lee, H‐J Kim, S‐D Cho, HM Kim Tags: Original Article Source Type: research