• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

ED misdiagnosis of cerebrovascular events in the era of modern neuroimaging: A meta-analysis
Conclusions: Roughly 9% of cerebrovascular events are missed at initial ED presentation. Risk of misdiagnosis is much greater when presenting neurologic complaints are mild, nonspecific, or transient (range 24%–60%). This difference suggests that many misdiagnoses relate to symptom-specific factors. Future research should emphasize studying causes and designing error-reduction strategies in symptom-specific subgroups at greatest risk of misdiagnosis.
Source: Neurology - April 10, 2017 Category: Neurology Authors: Tarnutzer, A. A., Lee, S.-H., Robinson, K. A., Wang, Z., Edlow, J. A., Newman-Toker, D. E. Tags: Stroke prevention, All Cerebrovascular disease/Stroke, Clinical trials Systematic review/meta analysis, Infarction, Subarachnoid hemorrhage VIEWS & amp;amp; REVIEWS Source Type: research

Teaching NeuroImages: HIV-associated cerebral vasculopathy with multiple nodular aneurysms
HIV-associated cerebral vasculopathy with multiple aneurysms has been widely reported in children1 and has to be considered in HIV-infected patients with high CSF viral load, but only few cases in adults have been published so far. Nodular and fusiform aneurysms (figure, A–D) are a typical imaging finding2 that may lead to suspicion of an autoimmune etiology by mimicking polyarteritis nodosa. These aneurysms might carry clinical significance with regard to the risk of subarachnoid or intracerebral hemorrhage, or causing infarction through formation of emboli. Highly active antiretroviral therapy leads to remission of...
Source: Neurology - April 3, 2017 Category: Neurology Authors: Seiler, A., You, S.-J., Wagner, M., Klein, J. C. Tags: Stroke in young adults, All Imaging, Vasculitis, HIV, All Cerebrovascular disease/Stroke RESIDENT AND FELLOW SECTION Source Type: research

Teaching NeuroImages: Intracranial arterial dissection
A 22-year-old previously fit man presented with acute seizures, left hemiparesis, and a Glasgow Coma Scale score of 7.
Source: Neurology - March 19, 2017 Category: Neurology Authors: Hermes, J., Lakshmanan, R., Watkins, L., Davagnanam, I. Tags: Stroke in young adults, Other cerebrovascular disease/ Stroke, All Cerebrovascular disease/Stroke, Infarction, Subarachnoid hemorrhage RESIDENT AND FELLOW SECTION Source Type: research

Phenotype and neuroimaging in cerebral amyloid angiopathy: More blood
Underpinned by clinical observation, cerebral amyloid angiopathy (CAA) has emerged from the doldrums of relatively little research activity to take center stage as a prototype in the application of pathologic, genetic, and neuroimaging studies.1 Initially identified as a frequent accompaniment of Alzheimer disease, CAA has revealed its own contribution to dementia, lobar hemorrhage, transient focal neurologic episodes (TFNEs), and encephalopathy associated with CAA inflammation or β-amyloid angiitis. Radiologic research, particularly with the application of blood-sensitive MRI sequences, has complemented pathologic st...
Source: Neurology - February 26, 2017 Category: Neurology Authors: McCarron, M. O., Smith, E. E. Tags: MRI, All Cerebrovascular disease/Stroke, Intracerebral hemorrhage, Subarachnoid hemorrhage EDITORIALS Source Type: research

Teaching NeuroImages: Superficial siderosis due to a dural cervical arteriovenous fistula
A 58-year-old man presented to our hospital with cerebellar ataxia, pyramidal signs, dysarthria, bilateral deafness, and cognitive impairment. These symptoms were consistent with superficial siderosis (SS) of the CNS, confirmed by MRI (figure A).1 Cerebral angiography showed a dural arteriovenous fistula perispinal and pontic with venous drainage in the left foramen C1-C2, fed by meningeal branches of the vertebral artery (figure, B). The fistulous point was clipped. SS of CNS is a rare disease resulting from hemosiderin deposition on the surface of the CNS and cranial nerves.2 At diagnosis, the etiology may...
Source: Neurology - February 19, 2017 Category: Neurology Authors: Madkouri, R., Grelat, M. Tags: All Cerebrovascular disease/Stroke, All Spinal Cord, Arteriovenous malformation, Subarachnoid hemorrhage RESIDENT AND FELLOW SECTION Source Type: research

Avoidance of steroids in the reversible cerebral vasoconstriction syndrome
Reversible cerebral vasoconstriction syndrome (RCVS), characterized by multifocal constrictions of cerebral arteries resolving spontaneously within 3 months, most commonly presents with unusual, severe, mostly thunderclap headaches (severe pain peaking in less than 1 minute).1,2 Seizures and focal neurologic deficits related to cortical subarachnoid hemorrhage, intracerebral hemorrhage, ischemic stroke, or posterior reversible encephalopathy syndrome may occur.3–5 Treatment relies on rest; withdrawal of any vasoactive drugs; avoidance of triggering factors; administration of nimodipine, given by analogy to aneurysmal...
Source: Neurology - January 15, 2017 Category: Neurology Authors: Mawet, J. Tags: All Headache, Stroke in young adults, All Imaging, Vasculitis, All Cerebrovascular disease/Stroke EDITORIALS Source Type: research

Large-scale identification of patients with cerebral aneurysms using natural language processing
Conclusions: We harnessed the power of the EMR by applying NLP to obtain a large cohort of patients with intracranial aneurysms and their matched controls. Such algorithms can be generalized to other diseases for epidemiologic and genetic studies.
Source: Neurology - January 8, 2017 Category: Neurology Authors: Castro, V. M., Dligach, D., Finan, S., Yu, S., Can, A., Abd-El-Barr, M., Gainer, V., Shadick, N. A., Murphy, S., Cai, T., Savova, G., Weiss, S. T., Du, R. Tags: All Cerebrovascular disease/Stroke, All epidemiology, Subarachnoid hemorrhage ARTICLE Source Type: research

Teaching NeuroImages: Intracranial vertebral dissection in a 15-year-old boy with sickle cell disease
A 15-year-old boy with sickle cell disease became unresponsive after sudden-onset headache. There was no antecedent trauma. A head CT scan demonstrated subarachnoid hemorrhage at the medulla (figure). Magnetic resonance angiography of the head and neck identified the patient's known bilateral internal carotid artery stenosis (a moyamoya-like arteriopathy associated with stroke in sickle cell disease) and a new right vertebral artery dissection, which was confirmed on conventional angiography (figure). Prior MRI performed as part of routine cerebral monitoring did not reveal any preexisting abnormality of the vertebral artery.
Source: Neurology - December 11, 2016 Category: Neurology Authors: Siegler, J. E., Banwell, B., Ichord, R. N. Tags: Pediatric stroke; see Cerebrovascular Disease/ Childhood stroke RESIDENT AND FELLOW SECTION Source Type: research

Teaching NeuroImages: Multicompartmental intracranial hemorrhage in a pediatric patient
A previously healthy 9-year-old girl presented with sudden-onset headache followed by confusion. In the emergency department, she was hypertensive, bradycardic, and no longer responsive to any stimuli. An emergent head CT scan demonstrated a left frontal intraparenchymal hematoma with intraventricular and subarachnoid extension as well as subfalcine herniation (figure). She underwent decompressive hemicraniectomy, and digital subtraction angiography confirmed a 7-mm left middle cerebral artery aneurysm (figure).
Source: Neurology - December 4, 2016 Category: Neurology Authors: Siegler, J. E., Ichord, R. N. Tags: Childhood stroke, Intracerebral hemorrhage, Subarachnoid hemorrhage RESIDENT AND FELLOW SECTION Source Type: research

Stable incidence but declining case-fatality rates of subarachnoid hemorrhage in a population
Conclusions: Although the incidence of SAH remained stable in this population-based region, 5-day, 30-day, and 90-day case-fatality rates declined significantly. Advances in surgical and medical management, along with systems-based changes such as the emergence of neurocritical care units, are potential explanations for the reduced case-fatality.
Source: Neurology - November 20, 2016 Category: Neurology Authors: Mackey, J., Khoury, J. C., Alwell, K., Moomaw, C. J., Kissela, B. M., Flaherty, M. L., Adeoye, O., Woo, D., Ferioli, S., De Los Rios La Rosa, F., Martini, S., Khatri, P., Broderick, J. P., Zuccarello, M., Kleindorfer, D. Tags: Outcome research, Subarachnoid hemorrhage ARTICLE Source Type: research

Cortical superficial siderosis predicts early recurrent lobar hemorrhage
Conclusions: Disseminated cSS on MRI and cSAH on CT are independent imaging markers of increased risk for early recurrent ICH. These markers may provide additional insights into the mechanisms of ICH recurrence in patients with CAA.
Source: Neurology - October 30, 2016 Category: Neurology Authors: Roongpiboonsopit, D., Charidimou, A., William, C. M., Lauer, A., Falcone, G. J., Martinez-Ramirez, S., Biffi, A., Ayres, A., Vashkevich, A., Awosika, O. O., Rosand, J., Gurol, M. E., Silverman, S. B., Greenberg, S. M., Viswanathan, A. Tags: All Cerebrovascular disease/Stroke, Intracerebral hemorrhage, Subarachnoid hemorrhage ARTICLE Source Type: research

Body mass index and stroke in UK women: "Obesity paradox" revisited
Obesity is a major risk factor for stroke. However, several studies have reported a protective effect of obesity on stroke, particularly after a prior cardiovascular event, a phenomenon described as the "obesity paradox" or "reverse epidemiology."1 No convincing biological evidence explains this paradox. The evidence that increased body mass index (BMI) increases risk for ischemic stroke in Western and Asian populations is strong, but the relationship with hemorrhagic stroke remains less established.
Source: Neurology - October 2, 2016 Category: Neurology Authors: Rexrode, K., Rundek, T. Tags: All Cerebrovascular disease/Stroke, Cohort studies, Risk factors in epidemiology, Intracerebral hemorrhage, Subarachnoid hemorrhage EDITORIALS Source Type: research

Adiposity and ischemic and hemorrhagic stroke: Prospective study in women and meta-analysis
Conclusions: In UK women, higher BMI is associated with increased risk of ischemic stroke but decreased risk of hemorrhagic stroke. The totality of the available published evidence suggests that BMI-associated risks are greater for ischemic than for hemorrhagic stroke.
Source: Neurology - October 2, 2016 Category: Neurology Authors: Kroll, M. E., Green, J., Beral, V., Sudlow, C. L. M., Brown, A., Kirichek, O., Price, A., Yang, T. O., Reeves, G. K., For the Million Women Study Collaborators Tags: All Cerebrovascular disease/Stroke, Cohort studies, Risk factors in epidemiology, Intracerebral hemorrhage, Subarachnoid hemorrhage ARTICLE Source Type: research

Subarachnoid hemorrhage: Another reason not to smoke
Subarachnoid hemorrhage (SAH) has high morbidity and mortality1 and represents a serious and substantial personal and public health burden. Therefore, we need studies of incidence, mortality, and risk factors to understand the disease and enable primary preventive measures.
Source: Neurology - September 11, 2016 Category: Neurology Authors: Sandvei, M. S., Sen, S. Tags: Stroke prevention, All Cerebrovascular disease/Stroke, Incidence studies, Subarachnoid hemorrhage EDITORIALS Source Type: research

Incidence of subarachnoid hemorrhage is decreasing together with decreasing smoking rates
Conclusions: The incidence of SAH seems to be decreasing. This tendency may be coupled with changes in smoking rates. The incidence of SAH in Finland is similar to other Nordic countries.
Source: Neurology - September 11, 2016 Category: Neurology Authors: Korja, M., Lehto, H., Juvela, S., Kaprio, J. Tags: Stroke prevention, All Cerebrovascular disease/Stroke, Incidence studies, Subarachnoid hemorrhage ARTICLE Source Type: research

Pages: 1  2  3  4  5  6  7  8