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The Role of Serum Calcium Level in Intracerebral Hemorrhage Hematoma Expansion: Is There Any?
AbstractSpontaneous intracerebral hemorrhage (ICH) is a devastating form of stroke, with a high rate of mortality and morbidity. Even with the best current medical or surgical interventions, outcomes remain poor. The location and initial hematoma volume are strong predictors of mortality. Hematoma expansion (HE) is a further marker of poor prognosis that may be at least partly preventable. Several risk factors for HE have been identified, including baseline ICH volume, anticoagulation, and computed tomography angiography spot signs. Recent studies have shown the correlation of serum calcium (Ca++) levels on admission with ...
Source: Neurocritical Care - June 27, 2018 Category: Neurology Source Type: research

Resolution of Cerebral Inflammation Following Subarachnoid Hemorrhage
ConclusionsBy the herein presented molecular and histological data we provide an important indication for an incomplete resolution of inflammation within the brain parenchyma after SAH. Inflammatory resolution and the return to tissue homeostasis represent an important contribution to the disease ’s pathology influencing the impact on brain damage and outcome after SAH. Therefore, we consider a novel complementary or even superior therapeutic approach that should be carefully rethought in the management of cerebral inflammation after SAH. An acceleration of the resolution phase at the cell ular and molecular levels could...
Source: Neurocritical Care - June 22, 2023 Category: Neurology Source Type: research