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Source: Annals of Neurology
Condition: Hemorrhagic Stroke
Management: National Institutes of Health (NIH)

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Total 4 results found since Jan 2013.

Clinical outcomes depending on acute blood pressure after cerebral hemorrhage
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Source: Annals of Neurology - November 12, 2018 Category: Neurology Authors: Kazunori Toyoda, Masatoshi Koga, Haruko Yamamoto, Lydia Foster, Yuko Y Palesch, Yongjun Wang, Nobuyuki Sakai, Takayuki Hara, Chung Y Hsu, Ryo Itabashi, Shoichiro Sato, Mayumi Fukuda, Thorsten Steiner, Byung ‐Woo Yoon, Daniel F Hanley, Adn Tags: Research Article Source Type: research

Neuroimaging and clinical outcomes of oral anticoagulant –associated intracerebral hemorrhage
ObjectiveWhether intracerebral hemorrhage (ICH) associated with non –vitamin K antagonist oral anticoagulants (NOAC‐ICH) has a better outcome compared to ICH associated with vitamin K antagonists (VKA‐ICH) is uncertain.MethodsWe performed a systematic review and individual patient data meta ‐analysis of cohort studies comparing clinical and radiological outcomes between NOAC‐ICH and VKA‐ICH patients. The primary outcome measure was 30‐day all‐cause mortality. All outcomes were assessed in multivariate regression analyses adjusted for age, sex, ICH location, and intraventricul ar hemorrhage extension.Results...
Source: Annals of Neurology - October 25, 2018 Category: Neurology Authors: Georgios Tsivgoulis, Duncan Wilson, Aristeidis H. Katsanos, Jo ão Sargento‐Freitas, Cláudia Marques‐Matos, Elsa Azevedo, Tomohide Adachi, Christian Brelie, Yoshifusa Aizawa, Hiroshi Abe, Hirofumi Tomita, Ken Okumura, Joji Hagii, David J Tags: Research Article Source Type: research

Prospective, open ‐label safety study of intravenous recombinant tissue plasminogen activator in wake‐up stroke
ObjectiveIt is estimated that one of four ischemic strokes are noticed upon awakening and are not candidates for intravenous recombinant tissue plasminogen activator (rtPA) because their symptoms are >3 hours from last seen normal (LSN). We tested the safety of rtPA in a multicenter, single‐arm, prospective, open‐label study (NCT01183533) in patients with wake‐up stroke (WUS). MethodsWe aimed to enroll 40 WUS patients with disabling deficits. Patients were 18 to 80 years of age, National Institutes of Health Stroke Scale (NIHSS) ≤25, and selected only on the appearance of noncontrast computed tomography (ie, ove...
Source: Annals of Neurology - July 11, 2016 Category: Neurology Authors: Andrew D. Barreto, Christopher V. Fanale, Andrei V. Alexandrov, Kevin C. Gaffney, Farhaan S. Vahidy, Claude B. Nguyen, Amrou Sarraj, Mohammad Rahbar, James C. Grotta, Sean I. Savitz, Tags: Research Article Source Type: research

Prospective, open‐label safety study of intravenous recombinant tissue plasminogen activator in wake‐up stroke
ObjectiveIt is estimated that one of four ischemic strokes are noticed upon awakening and are not candidates for intravenous recombinant tissue plasminogen activator (rtPA) because their symptoms are >3 hours from last seen normal (LSN). We tested the safety of rtPA in a multicenter, single‐arm, prospective, open‐label study (NCT01183533) in patients with wake‐up stroke (WUS). MethodsWe aimed to enroll 40 WUS patients with disabling deficits. Patients were 18 to 80 years of age, National Institutes of Health Stroke Scale (NIHSS) ≤25, and selected only on the appearance of noncontrast computed tomography (ie, ove...
Source: Annals of Neurology - July 11, 2016 Category: Neurology Authors: Andrew D. Barreto, Christopher V. Fanale, Andrei V. Alexandrov, Kevin C. Gaffney, Farhaan S. Vahidy, Claude B. Nguyen, Amrou Sarraj, Mohammad Rahbar, James C. Grotta, Sean I. Savitz, Tags: Research Article Source Type: research