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Source: Neurology
Condition: Hemorrhagic Stroke
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Total 691 results found since Jan 2013.
Early Clinical Improvement in Central Retinal Artery Occlusion is Associated with Central Retinal Artery Recanalization (P4.262)
Conclusions:In our case series, no patient without early recanalization of the CRA had ECI. Further studies are merited to determine the impact of CRA recanalization timing and, furthermore, whether fibrinolytic therapy is associated with improved CRA recanalization rates and long-term visual acuity in CRAO patients.Disclosure: Dr. Alkuwaiti has nothing to disclose. Dr. Male has nothing to disclose. Dr. Hendriksen has nothing to disclose. Dr. Engel has nothing to disclose. Dr. Reshi has nothing to disclose. Dr. Ezzeddine has received personal compensation for activities with Air Liquide as a Scientific Advisory Board membe...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Alkuwaiti, M., Male, S., Hendriksen, S., Engel, K., Reshi, R. A., Ezzeddine, M., Emiru, T., Logue, C., Streib, C. Tags: Thrombolysis and Acute Evaluation in Ischemic Stroke Source Type: research
Intravenous Thrombolysis for Acute Ischemic Stroke in Patients with Thrombocytopenia (P4.264)
Conclusions:IV rtPA for AIS might be safe in patients with platelet count <100,000/mm3 and it is reasonable not to delay IV rtPA administration while waiting for the platelet count result, unless there is strong suspicion for abnormal platelet count .Disclosure: Dr. Mowla has nothing to disclose. Dr. Kamal has nothing to disclose. Dr. Lail has nothing to disclose. Dr. Vaughn has nothing to disclose. Dr. Mehla has nothing to disclose. Dr. Deline has nothing to disclose. Dr. Ching has nothing to disclose. Dr. Crumlish has nothing to disclose. Dr. Sawyer has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Mowla, A., Kamal, H., Lail, N., Vaughn, C., Mehla, S., Deline, C., Ching, M., Crumlish, A., Sawyer, R. Tags: Thrombolysis and Acute Evaluation in Ischemic Stroke Source Type: research
Imaging predictors of hemorrhagic transformation following intravenous rt-PA treatment for acute ischemic stroke. (P4.266)
Conclusions:Presence of one or more chronic microbleeds is associated with increased risk of HT following rt-PA administration.Disclosure: Dr. Tasneem has nothing to disclose. Dr. Shaban has nothing to disclose. Dr. Dandapat has nothing to disclose. Dr. Ahmed has nothing to disclose. Dr. Policeni has nothing to disclose. Dr. Olalde has nothing to disclose. Dr. Samaniego has nothing to disclose. Dr. Shim has nothing to disclose. Dr. Pieper has nothing to disclose. Dr. Leira has nothing to disclose. Dr. Ortega-Gutierrez has nothing to disclose. Dr. Adams has nothing to disclose. Dr. Nagaraja has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Tasneem, N., Shaban, A., Dandapat, S., Ahmed, U., Policeni, B., Olalde, H., Samaniego, E., Shim, H., Pieper, C., Leira, E. C., Ortega-Gutierrez, S., Adams, H. P., Nagaraja, N. Tags: Thrombolysis and Acute Evaluation in Ischemic Stroke Source Type: research
Symptomatic Intracranial Hemorrhage after IV tPA for Acute Ischemic Stroke Patients with Relative Contraindications to Treatment (P4.267)
Conclusions:12 AIS patients with Class 3 exclusion criteria were treated with IV tPA. Our eight cases of IV tPA in pICH patients adds substantially to the existing literature. In this study, 25% of patients with pICH developed symptomatic ICH after IV tPA. Although the low number of eligible patients limits interpretation of our findings, continued caution when considering IV tPA for AIS patients with pICH may be warranted. More data is needed to clarify the impact these relative contraindications have on the treatment of AIS.Disclosure: Dr. Smith has nothing to disclose. Dr. Alkuwaiti has nothing to disclose. Dr. Bell has...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Smith, K., Alkuwaiti, M., Bell, C., Lindsay, D., Heyer, A., Reshi, R., Ezzeddine, M., Streib, C. Tags: Thrombolysis and Acute Evaluation in Ischemic Stroke Source Type: research
Patient is Taking Antiplatelet at home-Does This Increase the Risk of Post Intravenous Thrombolysis Intracranial Hemorrhage? (P4.268)
Conclusions:Patients with AIS receiving long-term antiplatelet medications were not at greater risk of developing sICH after IVT, neither did increase the chance of poor functional outcome.Disclosure: Dr. Mehla has nothing to disclose. Dr. Lail has nothing to disclose. Dr. Shah has nothing to disclose. Dr. Vaughn has nothing to disclose. Dr. Crumlish has nothing to disclose. Dr. Deline has nothing to disclose. Dr. Ching has nothing to disclose. Dr. Sawyer has nothing to disclose. Dr. Mowla has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Mehla, S., Lail, N., Shah, H., Vaughn, C., Crumlish, A., Deline, C., Ching, M., Sawyer, R., Mowla, A. Tags: Thrombolysis and Acute Evaluation in Ischemic Stroke Source Type: research
Impact of Vascular Risk factors on Hemorrhagic Transformation Following rt-PA Administration for Acute Ischemic Stroke (P4.269)
Conclusions:No vascular risk factor was independently associated with HT, suggesting a confounding effect from stroke severity (NIHSS score).Disclosure: Dr. Shaban has nothing to disclose. Dr. Tasneem has nothing to disclose. Dr. Dandapat has nothing to disclose. Dr. Ahmed has nothing to disclose. Dr. Policeni has nothing to disclose. Dr. Olalde has nothing to disclose. Dr. Samaniego has nothing to disclose. Dr. Shim has nothing to disclose. Dr. Pieper has nothing to disclose. Dr. Leira has nothing to disclose. Dr. Ortega-Gutierrez has nothing to disclose. Dr. Adams has nothing to disclose. Dr. Nagaraja has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Shaban, A., Tasneem, N., Dandapat, S., Ahmed, U., Policeni, B., Olalde, H., Samaniego, E., Shim, H., Pieper, C., Leira, E., Ortega-Gutierrez, S., Adams, H., Nagaraja, N. Tags: Thrombolysis and Acute Evaluation in Ischemic Stroke Source Type: research
Intravenous Thrombolysis in Anticoagulated and Thrombocytopenic Ischemic Stroke Patients Does Not Increase the Risk of Intracerebral Hemorrhage (P4.271)
Conclusions:These data suggest that IV rt-PA can be safely administered in coagulopathic and thrombocytopenic patients. Although rates of sICH and mortality were similar to the NINDS cohort, caution may be needed to identify certain hemorrhagic risk factors. Routine exclusion of anticoagulated or thrombocytopenic patients is not supported and the use of IV rt-PA in these patients may increase the eligibility for acute stroke therapy, particularly at institutions where IA therapy is unavailable.Disclosure: Dr. Barazangi has received personal compensation for activities with Genentech. Dr. Sorensen has nothing to disclose. D...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Barazangi, N., Sorensen, S., Chen, C., Wong, C., Yee, A., Ke, M., Rose, J., Grosvenor, D., Bedenk, A., Fernandes, J., Tong, D. Tags: Thrombolysis and Acute Evaluation in Ischemic Stroke Source Type: research
Trends in Alteplase Utilization in Louisianas Level III Hospitals (P4.272)
Conclusions:The treatment rate is increasing in Level III hospitals in Louisiana and is higher than the latest national Primary Stroke Center rate. Half of registered patients presented within 4.5hrs of LSN. Documentation of the reason for not getting alteplase improved. The disability associated with perceived minimal deficits is a target for enhanced education in determining eligibility for alteplase.Disclosure: Dr. Navalkele has nothing to disclose. Dr. Hargrove has nothing to disclose. Dr. Chernyshev has nothing to disclose. Dr. Acosta has nothing to disclose. Dr. DeAlvare has nothing to disclose. Dr. Hidalgo has nothi...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Navalkele, D., Hargrove, P., Chernyshev, O., Acosta, J., DeAlvare, L., Hidalgo, G., El Khoury, R., Martin-Schild, S. Tags: Thrombolysis and Acute Evaluation in Ischemic Stroke Source Type: research
Intravenous thrombolytic treatment of acute ischemic stroke in patients older and younger than 80 years: experience from one hospital (p4.275)
Conclusions:We found that IV thrombolysis still has benefit in people older than 80 years old but treatment decision should be taken with caution in well selected cases.Study Supported by: Not applicableDisclosure: Dr. Bayona has nothing to disclose. Dr. Diaz-Cruz has received research support from EMD Serono and Verily. Dr. Valencia-Mendoza has nothing to disclose. Dr. Díaz has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Bayona, H., Diaz-Cruz, C., Valencia-Mendoza, C., Diaz, A. Tags: Thrombolysis and Acute Evaluation in Ischemic Stroke Source Type: research
Risk of Symptomatic Intracranial Hemorrhage and Clinical Outcome after Intravenous Thrombolysis in Posterior Circulation Stroke: Results from the SITS-EAST Registry (P4.276)
Conclusions:In patients treated with IVT, data from SITS-EAST registry showed that localization of stroke in the posterior circulation was associated with better 90-day clinical outcome than in the anterior circulation. Nevertheless, the risk of SICH was only statistically insignificantly lower in PCS versus ACS patients.Disclosure: Dr. Herzig received personal compensation from Boehringer Ingelheim for serving on a scientific advisory board. Dr. Waishaupt has nothing to disclose. Dr. Belaskova has nothing to disclose. Dr. Vitkova has nothing to disclose. Dr. Blejcharova has nothing to disclose. Dr. Geier has nothing to di...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Herzig, R., Waishaupt, J., Belaskova, S., Vitkova, E., Blejcharova, K., Geier, P., Tomek, A., Bar, M., Vaclavik, D., Mikulik, R., Valis, M. Tags: Thrombolysis and Acute Evaluation in Ischemic Stroke Source Type: research
Hispanic patients have longer door-to-needle times independent of age, gender and stroke severity (P4.279)
Conclusions:There is a significant delay in DTN times for Hispanic ischemic stroke patients who received tPA with an average of 12 minute delay compared to non-Hispanic White patients. This relationship was independent of age, sex, and stroke severity. We speculate this may be due to language barriers.Disclosure: Dr. Liang has nothing to disclose. Dr. Cauchi has nothing to disclose. Dr. Boniece has nothing to disclose. Dr. Dhamoon has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Cauchi, J., Liang, J., Boniece, I., Dhamoon, M. Tags: Thrombolysis and Acute Evaluation in Ischemic Stroke Source Type: research
Intrapartum thrombolysis in acute stroke patient (P3.295)
Conclusions:The AHA/ASA guidelines recommend alteplase for moderate to severe strokes in pregnancy provided the benefit justifies the potential risk to the fetus and mother. Although, we report successful administration of intravenous alteplase during active labor without any complication to mother and baby, more data is needed to confirm the efficacy and safety in this patient population. A retrospective cohort study of 15 cases of alteplase in pregnancy did not demonstrate any increase in adverse events when compared to the non-pregnant females but none of them were in labor.Disclosure: Dr. Kohli has nothing to disclose....
Source: Neurology - April 17, 2017 Category: Neurology Authors: Kohli, D., Shekhar, S., Sreenivasan, V., Sugg, R. Tags: Cerebrovascular Disease Case Reports II Source Type: research
Endovascular Therapy for Acute Ischemic Stroke with Distal Middle Cerebral Artery Occlusion; A Case Series (P3.300)
Conclusions:Our initial experience suggests that successful recanalization of M2 and M3 occlusion with EVT is feasible and safe. Larger studies would help identifying benefit of EVT in this subset of intracranial occlusions.Disclosure: Dr. Suriya has nothing to disclose. Dr. Quadri has nothing to disclose. Dr. Taqi has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Suriya, S., Quadri, S., Taqi, M. Tags: Cerebrovascular Disease Case Reports II Source Type: research
Fetal central nervous system malformations: a ten year review of prenatal consultations at a tertiary care center (P4.150)
Conclusions:Neurodevelopmental outcomes ranged over a wide spectrum. Prenatal counseling includes cautious consideration of parental expectations, available long-term data on neurodevelopment and functional outcomes, limitations of neuroimaging and genetic testing, and critical decision making from both clinicians and families. This study aims to develop a standardized and comprehensive approach for fetal neurologic prognostication for neurodevelopmental outcomes, and for timely decision making in the prenatal and postnatal period.Disclosure: Dr. Agarwal has nothing to disclose. Dr. Keller has nothing to disclose. Dr. Clar...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Agarwal, S., Keller, J., Clark, G., Emrick, L. Tags: Child Neurology II Source Type: research
Post-Stroke Disability at a National Referral Hospital in Tanzania (P3.322)
Conclusions:In this low-resource setting, individuals with stroke face a severe burden of disability and high risk of mortality. The majority of participants experienced severe deficits following stroke, as assessed through NIHSS and mRS. While this study may be limited by referral bias, the high toll of disability among this population suggests that post-stroke disability places a significant burden on Tanzanian families and society.Study Supported by:This abstract was made possible with help from the Harvard University Center for AIDS Research (CFAR), an NIH funded program (P30 AI060354), subgrant to F. Mateen.Disclosure...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Wibecan, L., Mmbando, T., Grundy, S., Klein, J., Mateen, F., Okengo, K. Tags: Global Health Source Type: research
