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Source: Neurology
Condition: Hemorrhagic Stroke

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Total 691 results found since Jan 2013.

Symptomatic Intracranial Hemorrhage after IV tPA for Acute Ischemic Stroke Patients with Relative Contraindications to Treatment (P4.267)
Conclusions:12 AIS patients with Class 3 exclusion criteria were treated with IV tPA. Our eight cases of IV tPA in pICH patients adds substantially to the existing literature. In this study, 25% of patients with pICH developed symptomatic ICH after IV tPA. Although the low number of eligible patients limits interpretation of our findings, continued caution when considering IV tPA for AIS patients with pICH may be warranted. More data is needed to clarify the impact these relative contraindications have on the treatment of AIS.Disclosure: Dr. Smith has nothing to disclose. Dr. Alkuwaiti has nothing to disclose. Dr. Bell has...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Smith, K., Alkuwaiti, M., Bell, C., Lindsay, D., Heyer, A., Reshi, R., Ezzeddine, M., Streib, C. Tags: Thrombolysis and Acute Evaluation in Ischemic Stroke Source Type: research

Impact of Vascular Risk factors on Hemorrhagic Transformation Following rt-PA Administration for Acute Ischemic Stroke (P4.269)
Conclusions:No vascular risk factor was independently associated with HT, suggesting a confounding effect from stroke severity (NIHSS score).Disclosure: Dr. Shaban has nothing to disclose. Dr. Tasneem has nothing to disclose. Dr. Dandapat has nothing to disclose. Dr. Ahmed has nothing to disclose. Dr. Policeni has nothing to disclose. Dr. Olalde has nothing to disclose. Dr. Samaniego has nothing to disclose. Dr. Shim has nothing to disclose. Dr. Pieper has nothing to disclose. Dr. Leira has nothing to disclose. Dr. Ortega-Gutierrez has nothing to disclose. Dr. Adams has nothing to disclose. Dr. Nagaraja has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Shaban, A., Tasneem, N., Dandapat, S., Ahmed, U., Policeni, B., Olalde, H., Samaniego, E., Shim, H., Pieper, C., Leira, E., Ortega-Gutierrez, S., Adams, H., Nagaraja, N. Tags: Thrombolysis and Acute Evaluation in Ischemic Stroke Source Type: research

Association of splenic contraction and development of SIRS after acute ischemic stroke. (P4.297)
Conclusions:Based on our initial evaluation, SC detected within 24 hrs of stroke onset is not associated with SIRS suggesting that the relationship between the two may be more complicated in humans. Consistent with prior studies, however, SIRS is associated with worse outcome. Further studies and additional time points are necessary to further clarify the role of the spleen in the development of SIRS in stroke patients.Disclosure: Dr. Zha has nothing to disclose. Dr. Tippinayani has nothing to disclose. Dr. Randhawa has nothing to disclose. Dr. Vahidy has nothing to disclose. Dr. Savitz has received research support from the NIH.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Zha, A., Tippinayani, B., Randhawa, J., Vahidy, F., Savitz, S. Tags: In-Hospital Stroke Care Source Type: research

Individualized risk prediction of major bleeding in secondary stroke prevention: Are we there yet?
In most patients diagnosed with a TIA or ischemic stroke, secondary stroke prevention relies on antiplatelet therapy unless anticoagulation is indicated. Aspirin has the largest evidence base and reduces the risk of early recurrent ischemic stroke without a major risk of early hemorrhagic complications.1 Because antiplatelet therapy typically continues for many years, clinicians and patients need an estimation of the annual bleeding risk to accurately assess future risk. In a meta-analysis of 25 randomized trials of antiplatelet therapy in primary or secondary prevention of cardiovascular disease, aspirin increased the abs...
Source: Neurology - August 28, 2017 Category: Neurology Authors: Lemmens, R., Al-Shahi Salman, R. Tags: Stroke prevention, All Cerebrovascular disease/Stroke, Risk factors in epidemiology, Infarction EDITORIALS Source Type: research

Outcome after stroke thrombolysis in patients >80 years treated within 3 hours vs >3-4.5 hours
Conclusions: In this observational study, unselected patients >80 years of age treated with IVT after 3 hours vs earlier had a slightly higher rate of SICH and similar unadjusted functional outcome but poorer adjusted outcome. The absolute difference between the treatment groups is small, and elderly patients should not be denied IVT in the later time window solely because of age without other contraindications.
Source: Neurology - October 9, 2017 Category: Neurology Authors: Ahmed, N., Lees, K. R., Ringleb, P. A., Bladin, C., Collas, D., Toni, D., Ford, G. A., And the SITS Investigators Tags: All Cerebrovascular disease/Stroke ARTICLE Source Type: research

Cross-Border Acute Ischemic Stroke Subtype Comparison Between Hispanics and Mexican Mestizos (P1.123)
CONCLUSIONS: Small artery ischemic strokes were the most common subtype in both MM and Hispanic patients, and occurred with a similar frequency in the two populations. This similarity could be a consequence of a high pre-existing condition of hypertension in both groups. A higher incidence of large vessel and cardioembolic ischemic strokes were seen in MM compared with Hispanics, which may reflect the higher number of patients with risk factors of smoking and atrial fibrillation in the MM group.Disclosure: Dr. Cerdan-Trevino has nothing to disclose. Dr. Cantu-Martinez has nothing to disclose. Dr. Mora-Villalvazo has nothin...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Cerdan-Trevino, M., Cantu-Martinez, L., Mora-Villalvazo, R., Martinez, H., Hughes, R., Poisson, S. Tags: Cerebrovascular Disease and Interventional Neurology: Ischemic Stroke Subtype Source Type: research

Thrombolytic Treatment for Acute Ischemic Stroke Patients with History of Migraine Headaches (P4.223)
Conclusion: Patients with migraine headaches receiving IV rt-PA treatment for acute ischemic stroke appear to have a lower rates of death and disability most likely related to their decreased rates of intracerebral hemorrhage.Disclosure: Dr. Malik has nothing to disclose. Dr. Malik has nothing to disclose. Dr. Nickles has nothing to disclose. Dr. Qureshi has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Malik, A., Adil, M., Chaudhry, S., Qureshi, A. Tags: Cerebrovascular Disease and Interventional Neurology: Acute Stroke Thrombolysis Source Type: research

Vitreous Hemorrhage as a Complication of IV-tPA Therapy in a Patient with Acute Stroke (P4.227)
CONCLUSIONS: To our knowledge, this is the first case report of vitreous hemorrhage following acute stroke therapy with IV-tPA. This underscores the risk of intraocular hemorrhage in patients with retinal neovascularization that could occur with other retinal vascular disorders such as diabetic retinopathy. The decision to proceed with IV-tPA in the presence of retinal neovascularization should be made on a case-by-case basis and further discussion with the patient.Disclosure: Dr. Shah has nothing to disclose. Dr. Verstraeten has nothing to disclose. Dr. Wright has nothing to disclose. Dr. Rana has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Shah, L., Verstraeten, T., Wright, D., Rana, S. Tags: Cerebrovascular Disease and Interventional Neurology: Acute Stroke Thrombolysis Source Type: research

The Discharge Modified Rankin Scale Score Correlates with Established Hemorrhagic Transformation Scores in Ischemic Stroke Patients Treated with Thrombolysis (P7.118)
Conclusions: Discharge MRS scores showed robust agreement with at least 3 HT scores known to predict long-term functional outcomes after IV rt-PA therapy. Therefore, readily available discharge MRS scores may be useful indicator of patients requiring closer follow-up after IV rt-PA therapy.Disclosure: Dr. Asuzu has nothing to disclose. Dr. Nystrom has nothing to disclose. Dr. Halliday has nothing to disclose. Dr. Wira has nothing to disclose. Dr. Greer has nothing to disclose. Dr. Pritchard has nothing to disclose. Dr. Schindler has nothing to disclose. Dr. Sheth has received research support from the American Academy of N...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Asuzu, D., Nystrom, K., Halliday, J., Wira, C., Greer, D., Pritchard, D., Schindler, J., Sheth, K. Tags: Cerebrovascular Disease and Interventional Neurology: Issues in Acute Stroke Treatment Source Type: research

Thrombolytic therapy for stroke in patients with preexisting cognitive impairment
Conclusions: Ischemic stroke patients with PSCI should receive rtPA if they are eligible. This conclusion cannot be extended to severe cognitive impairment or severe strokes. Classification of evidence: This study provides Class IV evidence that in patients with PSCI presenting with acute ischemic stroke, IV rtPA improves outcomes.
Source: Neurology - June 9, 2014 Category: Neurology Authors: Murao, K., Leys, D., Jacquin, A., Kitazono, T., Bordet, R., Bejot, Y., Kimura, K., Godefroy, O., Wakisaka, Y., Moulin, S., Ago, T., Sibon, I., Bombois, S., Mas, J.-L., Henon, H., Pasquier, F., Giroud, M., Cordonnier, C., Okada, Y., On behalf of the OPHELI Tags: All Cerebrovascular disease/Stroke, All Cognitive Disorders/Dementia, MCI (mild cognitive impairment), Infarction ARTICLE Source Type: research

Implication of Deep Versus Cortical Ischemia on DWI-ASPECTS In Anterior Circulation Large Vessel Occlusion Ischemic Stroke (P3.083)
Conclusions: Deep and cortical ischemic lesions defined by ASPECTS regions were independent predictors of poor outcome in ACLVO stroke. We did not observe a statistically significant difference between cortical and deep ischemia on clinical outcomes. Validation in a larger cohort is needed to confirm these findings.Disclosure: Dr. Streib has nothing to disclose. Dr. Rangaraju has nothing to disclose. Dr. Jadhav has nothing to disclose. Dr. Jovin has received personal compensation for activities with Covidein, Concentric Medical Inc., Stryker, and Silk Road Medical.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Streib, C., Rangaraju, S., Jadhav, A., Jovin, T. Tags: Cerebrovascular Disease and Interventional Neurology: Hemorrhagic and Ischemic Stroke Source Type: research

Arterial Reocclusion And Distal Embolization During Endovascular Treatment Using New Generation Stent Retrievers In Acute Ischemic Stroke Patients (P4.299)
CONCLUSIONS: Arterial reocclusion and distal embolization occur in 16[percnt]-18[percnt] of acute ischemic stroke patients undergoing mechanical thrombectomy with new stent retrievers. The rates are no higher than those observed in cohorts treated without stent retrievers.Disclosure: Dr. Herial has nothing to disclose. Dr. Qureshi has nothing to disclose. Dr. Khan has nothing to disclose. Dr. Jahangir has nothing to disclose. Dr. Zeb has nothing to disclose. Dr. Janjua has nothing to disclose. Dr. Suri has nothing to disclose. Dr. Qureshi has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Herial, N., Qureshi, M., Khan, A., Jahangir, N., Zeb, H., Janjua, N., Suri, M., Qureshi, A. Tags: Cerebrovascular Disease and Interventional Neurology: Acute Interventional Treatment for Ischemic Stroke Source Type: research

Post-stroke depression (PSD) in sub-Saharan Africans- validation of the Japanese stroke scale for depression. (JSS-D). (P7.129)
CONCLUSIONS:JSS-D could be used for PSD with acceptable sensitivity and specificity in sub-Saharan Africans. Study Supported by:NONEDisclosure: Dr. Imarhiagbe has nothing to disclose. Dr. Afolabi has nothing to disclose. Dr. Kubeyinje has nothing to disclose. Dr. AKEMOKWE has nothing to disclose. Dr. Odiase has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Imarhiagbe, F., Afolabi, O., Kubeyinje, A., Akemokwe, F., Odiase, F. Tags: Cerebrovascular Disease and Interventional Neurology: Stroke, Depression, and Anxiety Source Type: research

Recurrent vascular events in lacunar stroke patients with metabolic syndrome and/or diabetes
Conclusion: METS and DM were significant comorbid conditions in lacunar stroke patients and they were associated with stroke recurrence. In patients with lacunar infarcts, a vigilant approach to prevent development of DM in those with METS may be a potential strategy to reduce recurrent strokes.
Source: Neurology - September 14, 2015 Category: Neurology Authors: Zhu, S., McClure, L. A., Lau, H., Romero, J. R., White, C. L., Babikian, V., Nguyen, T., Benavente, O. R., Kase, C. S., Pikula, A. Tags: All Cerebrovascular disease/Stroke ARTICLE Source Type: research

Gaze Deviation and Acute Stroke Care Strategies (S16.005)
Conclusions: Gaze deviation is a good predictor of large artery occlusion and if present can positively predict hyperacute interventions. Incorporating their use in prehospital and increasing their weightage in a 'modified' NIHSS can be used as a strategy to reduce ‘the time of onset of symptoms to treatment’ in hyperacute stroke. Prehospital stroke scales that include gaze deviation sign may be useful in clinical practice.Disclosure: Dr. Mahdi has nothing to disclose. Dr. Trikannad Ashwini Kumar has nothing to disclose. Dr. Bhattacharya has nothing to disclose. Dr. Madhavan has nothing to disclose.
Source: Neurology - February 7, 2016 Category: Neurology Authors: Mahdi, Z., Trikannad Ashwini Kumar, A. K., Bhattacharya, P., Madhavan, R. Tags: Prehospital/Emergency Room Stroke Care and Intracerebral Hemorrhage Source Type: research