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O-042 Complications of DAPT cessation at 3 months versus 6 months after flow diversion of unruptured intracranial aneurysms
ConclusionsOnly 0.6% (n=1) of patients exhibited complications after 3 month follow-up. We conclude that DAPT duration of 3 months after endoluminal flow diversion of unruptured cerebral aneurysms of the anterior circulation is not associated with increased rates of hemorrhagic or thromboembolic complications compared to a traditional 6-month regimen.Disclosures S. Srinivasan: None. A. White: None. M. Al-Abdulkareem: None. J. Barr: None. L. Pride: None. J. White: None. R. Novakovic-White: None. R. Sillero: None. B. Welch: None.
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Srinivasan, S., White, A., Al-Abdulkareem, M., Barr, J., Pride, L., White, J., Novakovic-White, R., Sillero, R., Welch, B. Tags: SNIS 20th annual meeting oral abstracts Source Type: research

E-219 Direct vs indirect revascularization for moyamoya: a large multicenter study
ConclusionSince both modalities showed comparable rates of overall total strokes, both modalities of revascularization can be performed depending on the patient’s risk assessment.Abstract E-219 Table 1Direct Indirect Effect variable Value (95% confidence interval) P-value Primary Outcome Symptomatic stroke, n (%) 23/198 (11.6) 19/198 (9.6) Odds ratio 1.238 (0.651 - 2.354) 0.514 Secondary Outcomes Symptomatic ischemic stroke, n (%) 23/198 (11.6) 16/198 (8.1) Odds ratio 1.495 (0.764 - 2.924) 0.240 Symptomatic hemorrhagic stroke, n (%) 0/198 (0) 3/198 (1.5) –– –– 0.248 Peri-operative stroke,...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: El Naamani, K., Chen, C., Jabre, R., Saad, H., Grissberg, J., Dmytriw, A., Patel, A., Khorasanizadeh, M., Ogilvy, C., Thomas, A., Monteiro, A., Siddiqui, A., Cortez, G., Hanel, R., Porto, G., Spiotta, A., Piscopo, A., Hasan, D., Ghorbani, M., Weinberg, J. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

Comparing treatment outcomes of various intracranial bifurcation aneurysms locations using the Woven EndoBridge (WEB) device
Conclusion To our knowledge, this is the most extensive study to date that compares the treatment of different intracranial bifurcation aneurysms using the WEB device. Basilar tip and ICA bifurcation aneurysms showed significantly higher rates of aneurysm occlusion than other locations.
Source: Journal of NeuroInterventional Surgery - May 16, 2023 Category: Neurosurgery Authors: Adeeb, N., Dibas, M., Diestro, J. D. B., Phan, K., Cuellar-Saenz, H. H., Sweid, A., Lay, S. V., Guenego, A., Aslan, A., Renieri, L., Sundararajan, S. H., Saliou, G., Möhlenbruch, M., Regenhardt, R. W., Vranic, J. E., Lylyk, I., Foreman, P. M., Vac Tags: Hemorrhagic stroke Source Type: research

Bifurcation geometry remodelling of vessels in de novo and growing intracranial aneurysms: a multicenter study
Conclusion Our study suggests that wider bifurcation angles that have long been deemed causal factors for IA formation or growth may be secondary to IA formation at pathologic bifurcation sites. This finding has implications for our understanding of IA formation pathophysiology.
Source: Journal of NeuroInterventional Surgery - May 16, 2023 Category: Neurosurgery Authors: Boucherit, J., Kerleroux, B., Boulouis, G., Tessier, G., Rodriguez, C., Sporns, P. B., Ghannouchi, H., Shotar, E., Gariel, F., Marnat, G., Burel, J., Ifergan, H., Forestier, G., Rouchaud, A., Desal, H., Nouri, A., Autrusseau, F., Loirand, G., Bourcier, R. Tags: Hemorrhagic stroke Source Type: research

P79 Multicenter assessment of the Tigertriever 13 for thrombectomy in primary medium vessels occlusions
ConclusionMechanical thrombectomy using the Tigertriever 13 appears to be safe and effective for MeVO among different centers and physicians, as a first-line device or as a recue-therapy after an other approach failure.ReferencesGuenego A, Mine B, Bonnet T, et al. Thrombectomy for distal medium vessel occlusion with a new generation of stentretriever (tigertriever 13). Interv Neuroradiol 2021: 15910199211039926. 2021/09/14. DOI: 10.1177/15910199211039926. Do you have any conflict of interest to declare?: YesConflict of Interest StatementConsultancy for Rapid Medical (travel grant only)
Source: Journal of NeuroInterventional Surgery - August 29, 2022 Category: Neurosurgery Authors: Guenego, A., Lubicz, B., Dmytriw, A., Regenhardt, R., Diestro, J., Jabbour, P., Siegler, J., Gonzalez, N., Levitt, M., Tancredi, I., Rouchaud, A., Fiehler, J., Kan, P., Berge, J., Nedelcu, S., Ota, T., Yeo, L., Sheth, S., Collin, T., Renieri, L., Mowla, A Tags: 14th Congress of the European Society of Minimally Invasive Neurological Therapy 2022 Meeting Abstracts Source Type: research

LB003 Multicenter assessment of the tigertriever 13 for thrombectomy in primary medium vessels occlusions
ConclusionMechanical thrombectomy using the Tigertriever13 appears to be safe and effective for MeVO among different centers and physicians, as a first-line device or as a recue-therapy after an other approach failure.Disclosures A. guenego: 6; C; Travel Grant to PAIRS in Dubai by Rapid Medical. B. lubicz: None. A. Dmytriw: None. R. Regenhardt: None. J. diestro: None. V. pereira: None. P. jabbour: None. J. siegler: None. N. gonzalez: None. M. Levitt: None. I. Tancredi: None. A. Rouchaud: None. J. Fiehler: None. T. Faizy: None. P. Kan: None. X. barreau: None.
Source: Journal of NeuroInterventional Surgery - July 26, 2022 Category: Neurosurgery Authors: Guenego, A., Lubicz, B., Dmytriw, A., Regenhardt, R., Diestro, J., Pereira, V., Jabbour, P., Siegler, J., Gonzalez, N., Levitt, M., Tancredi, I., Rouchaud, A., Fiehler, J., Faizy, T., Kan, P., Barreau, X. Tags: SNIS 19th annual meeting late-breaking oral abstracts Source Type: research

E-138 Intracerebral hemorrhage in patients transferred for mechanical thrombectomy
ConclusionsIn a large series of stroke patients being specifically transferred for mechanical thrombectomy, the rate of ICH on arrival to the thrombectomy hospital was 1.2%. In less than 50% of those cases the decision to forgo intervention was related to the ICH finding. The results of our study adds to the concerns that repeat imaging delays treatment by demonstrating that the incidence of ICH is low, which may warrant reconsideration of current stroke workflows for large vessel occlusion transfers.Disclosures Y. Radaideh: None. K. Joshi: None. M. Chen: None.
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Radaideh, Y., Joshi, K., Chen, M. Tags: SNIS 19th annual meeting electronic poster abstracts Source Type: research

E-159 Neurointervention on distal MCA occlusions: a multi-center study demonstrating safety and efficacy
ConclusionNeurointervention in distal MCA strokes may be effective. Further prospective, randomized studies in larger cohorts are necessary to compare the efficacy and safety of this technique to other medical treatments of distal MCA strokes.Abstract E-159 Table 1Baseline Characteristics – Summary Statisticsn=228 Baseline ASPECTS 24h ASPECTS Age (mean, sd) 71.46, 14.62 0–5 2 10 Female (%) 115 (50.44%) 6–7 17 15 Location 8 22 13 L M2 122 9 57 22 L M3 21 10 96 13 R M2 81 Baseline NIHSS 24h NIHSS R M3 5 0–4 19 77 Baseline mRS (breakdown) 90 day mRS 5–8 50 28 mRS = 0 132 23 9–12 39 33 mR...
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Siddiqui, N., De Leacy, R. Tags: SNIS 19th annual meeting electronic poster abstracts Source Type: research

E-215 Single stent assisted coiling for wide neck bifurcation aneurysms: a multi-center core lab validated analysis demonstrating safety and efficacy
ConclusionThis study represents the first multi-center, core-lab validated data of the safety and efficacy of the L-stenting single stent technique for wide-neck bifurcation aneurysms. Further prospective studies in larger cohorts are necessary to compare the efficacy and safety of this treatment to other endovascular techniques for treatment of wide neck bifurcation aneurysms.Disclosures N. Siddiqui: None. R. De Leacy: None.
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Siddiqui, N., De Leacy, R. Tags: SNIS 19th annual meeting electronic poster abstracts Source Type: research

P-015 Implementation of a cognitive dysfunction screening protocol after aneurysmal subarachnoid hemorrhage
ConclusionWe successfully implemented an evidence-based screening protocol for cognitive dysfunction after aSAH. Most of these patients did exhibit cognitive dysfunction using the MoCA despite a good functional recovery, defined as mRS score <2. Screening only with the mRS is inadequate to identify the substantial cognitive dysfunction within this patient population. Further research is necessary to understand the impact of early cognitive intervention on long term outcomes for patients with cognitive impairment following aSAH.Disclosures N. Hall: None. J. Jackson: None. R. Chitale: None. M. Fusco: None. C. Considine: N...
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Hall, N., Jackson, J., Chitale, R., Fusco, M., Considine, C., Froehler, M. Tags: SNIS 19th annual meeting oral poster abstracts Source Type: research

P-019 Comparative effectiveness of stent-assisted coiling and woven endobridge (WEB) embolization for the treatment of unruptured wide-neck bifurcation intracranial aneurysms
ConclusionMid-term complete and adequate occlusion rates were similar between patients treated with WEB and SAC. Given the comparable outcomes, there may be equipoise in treatment options for WNBAs.Abstract P-019 Table 1Baseline patient and aneurysm morphology parameters between treatment groups Aneurysm parameters* WEB (n=27) Stent-coil (n=54) p-value Age 63 (50–69) 65 (57–69) 0.511 Gender, male 6 (22%) 12 (22%) 1.000 Smoking Status Current smoker 9 (33%) 9 (17%) 0.235 Prior Smoker 9 (33%) 22 (41%) Never Smoker 9 (33%) 23 (43%) Location Acomm 9 (33%) 20 (37%) 0.772 Basilar apex 6 (22%) 17 (32%) Carotid termin...
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Kashkoush, A., Desai, A., Davison, M., Achey, R., Mahapatra, A., Patterson, T., Moore, N., Bain, M. Tags: SNIS 19th annual meeting oral poster abstracts Source Type: research

Outcomes of endovascular thrombectomy in patients selected by computed tomography perfusion imaging - a matched cohort study comparing nonagenarians to younger patients
Conclusions Nonagenarians were noted to have greater mortality and sICH rates following EVT compared with matched younger patients, which may be ameliorated by selecting patients with smaller CTP core volumes. Nonagenarians undergoing EVT had similar rates of successful reperfusion and functional independence compared with the younger cohort.
Source: Journal of NeuroInterventional Surgery - July 14, 2022 Category: Neurosurgery Authors: Rahangdale, R., Hackett, C. T., Cerejo, R., Fuller, N. M., Malhotra, K., Williamson, R., Hentosz, T., Tayal, A. H., Rana, S. S. Tags: Editor''s choice, Ischemic stroke Source Type: research

Mortality after treatment of intracranial aneurysms with the Pipeline Embolization Device
Conclusions Delayed aneurysm rupture, distal intraparenchymal hemorrhage, and neurological compression were the main causes of mortality in patients with intracranial aneurysms treated with the PED. Large basilar aneurysms are associated with an increased risk of postoperative death and require increased attention and caution.
Source: Journal of NeuroInterventional Surgery - January 18, 2022 Category: Neurosurgery Authors: Kang, H., Luo, B., Liu, J., Zhang, H., Li, T., Song, D., Zhao, Y., Guan, S., Maimaitili, A., Wang, Y., Feng, W., Wang, Y., Wan, J., Mao, G., Shi, H., Wang, K., Yang, X. Tags: Hemorrhagic stroke Source Type: research

O-005 Comparison of on-label versus off-label treatment of intracranial aneurysms with the pipeline embolization devices
ConclusionIn real-world practice, off-label uses of PED can achieve similar safety and efficacy to on-label uses, though there may be a slightly higher rate of ischemic complications in off-label uses. Expert judgment is a useful supplement to official guidelines when assessing reasonable PED use beyond its approved indications.Disclosures S. Cler: None. D. Lauzier: None. A. Kansagra: 2; C; Penumbra, Microvention, iSchemaView.
Source: Journal of NeuroInterventional Surgery - July 26, 2021 Category: Neurosurgery Authors: Cler, S., Lauzier, D., Kansagra, A. Tags: Oral abstracts Source Type: research

E-008 Variation in subarachnoid hemorrhage presentation and demographics in California during the COVID-19 pandemic: A UC stroke consortium study
ConclusionsCOVID19(+) patients presenting with SAH were younger than COVID(-) controls, and there was a trend toward underrepresentation of Hispanic patients in the COVID(+) group. Recognizing COVID19 status as a factor in SAH presentation is important to mitigate healthcare disparities in California.Disclosures A. Gautam: None. T. Caton: None. K. Narsinh: None. A. Baker: None. S. Hetts: None. D. Cooke: None.
Source: Journal of NeuroInterventional Surgery - July 26, 2021 Category: Neurosurgery Authors: Gautam, A., Caton, T., Narsinh, K., Baker, A., Hetts, S., Cooke, D. Tags: Electronic poster abstracts Source Type: research

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