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Source: Current Cardiology Reports
Condition: Ischemic Stroke

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Total 42 results found since Jan 2013.

Correlation Between Cardiovascular Protection and Influenza Vaccination
AbstractPurpose of ReviewInfluenza is the cause of millions of deaths yearly in the USA and globally. It presents a significant health burden in millions of people and is associated with chronic disease exacerbations including acute cardiovascular events such as myocardial infarction and stroke. We reviewed recent studies and a meta-analysis to assess the part that influenza vaccination plays in cardiovascular system protection.Recent FindingsA sizable study measured the effect of influenza vaccination on cardiovascular health and mortality. This retrospective observational study used the 2012 –2015 US National Inpatient...
Source: Current Cardiology Reports - April 14, 2023 Category: Cardiology Source Type: research

Stroke in Atrial Fibrillation and Other Atrial Dysrhythmias
AbstractPurpose of ReviewAtrial fibrillation (AF) is a major risk factor for systemic embolism and ischaemic stroke. Furthermore, AF-related strokes are associated with higher mortality, greater disability, longer hospital stays and lower rates of hospital discharge than strokes caused by other reasons. The aim of this review to summarise the existing evidence on the association of AF with ischemic stroke and provide insights on the pathophysiological mechanisms and the clinical management of patients with AF in order to reduce the burden of ischemic stroke.Recent FindingsBeyond Virchow ’s triad, several pathophysiologic...
Source: Current Cardiology Reports - March 28, 2023 Category: Cardiology Source Type: research

Adding Fuel to the Fire: Infective Endocarditis and the Challenge of Cerebrovascular Complications
AbstractPurpose of ReviewInfective endocarditis is a deadly disease and made more deadly by neurologic complications. We review the cerebrovascular complications of infective endocarditis and focus our discussion on medical and surgical management.Recent FindingsWhile management of stroke in the setting of infective endocarditis differs from standard stroke treatment, mechanical thrombectomy has proven safe and successful. Optimal timing of cardiac surgery in the setting of stroke remains an area of debate, but additional observational studies continue to add more detail to the discussion.SummaryCerebrovascular complicatio...
Source: Current Cardiology Reports - March 27, 2023 Category: Cardiology Source Type: research

Concomitant Surgical Left Atrial Appendage Occlusion: a Review
AbstractPurpose of ReviewIn this review, we discuss some of the observational studies that examined the impact of left atrial appendage occlusion on stroke, the Left Atrial Appendage Occlusion Study (LAAOS) III research program that provided definitive evidence for the benefit of surgical left atrial appendage occlusion on ischemic stroke, and high priority studies in the field that should be pursued by the surgical community.Recent FindingsAtrial fibrillation is common in patients undergoing cardiac surgery. Oral anticoagulants are effective at preventing strokes related to atrial fibrillation; they have been the standard...
Source: Current Cardiology Reports - April 30, 2022 Category: Cardiology Source Type: research

Stroke Prevention in Patients with Patent Foramen Ovale
AbstractPurpose of ReviewPatent foramen ovale (PFO) is widely prevalent and studies have suggested an association with ischemic stroke. In this review, we aim to highlight current management of patients with ischemic stroke in the setting of PFO and discuss some areas of controversy.Recent FindingsUpon reviewing the literature, we have found that the evidence regarding the management of patients with cryptogenic stroke and PFO has come a long way in the past several years, and many uncertainties remain in clinical practice. The Risk of Paradoxical Embolism (RoPE) score helps to predict the probability of a pathogenic PFO, ...
Source: Current Cardiology Reports - October 30, 2021 Category: Cardiology Source Type: research

Stroke Prevention After Cryptogenic Stroke
AbstractPurpose of ReviewCryptogenic stroke represents a heterogenous but clinically important collection of stroke etiologies for which our understanding continues to grow. Here, we review our current knowledge and most recent recommendations on secondary prevention for common causes of cryptogenic stroke including paroxysmal atrial fibrillation, atrial cardiopathy, patent foramen ovale, and substenotic atherosclerotic disease as well as the under-recognized mechanisms of occult malignancy, heart failure, and, most recently, infection with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2).Recent FindingsThe res...
Source: Current Cardiology Reports - October 16, 2021 Category: Cardiology Source Type: research

Stroke Prevention with Extracranial Carotid Artery Disease
This article reviews contemporary treatments for carotid artery stenosis, the underlying evidence, and areas of uncertainties.Recent FindingsSpecific recommendations are available to guide the standard of care of carotid artery stenosis. Nonetheless, significant uncertainties are noted in patient selection for surgical treatment of asymptomatic carotid stenosis and in optimal treatment targets for pharmacological therapies. Advanced imaging has been used to predict future risk of ipsilateral stroke and clarify mechanisms of actions of pharmacological therapies, primarily in observational studies.SummaryPharmacological and ...
Source: Current Cardiology Reports - October 1, 2021 Category: Cardiology Source Type: research

Stroke Prevention After Intracerebral Hemorrhage: Where Are We Now?
The objective of this article is to review the current guidelines on stroke prevention measures after ICH as well as the new findings and controversies for future guidance.Recent FindingsIntensive blood pressure reduction might benefit ICH survivors significantly. Cholesterol levels and the risk of ICH have an inverse relationship, but statin therapy after ICH might be still beneficial. Anticoagulation in atrial fibrillation after ICH specifically with novel oral anticoagulants may be associated with better long-term outcomes. Left atrial appendage occlusion may be an alternative for stroke prevention in ICH survivors with...
Source: Current Cardiology Reports - October 1, 2021 Category: Cardiology Source Type: research

Stroke Prevention with Extracranial Carotid Artery Disease
This article reviews contemporary treatments for carotid artery stenosis, the underlying evidence, and areas of uncertainties.Recent FindingsSpecific recommendations are available to guide the standard of care of carotid artery stenosis. Nonetheless, significant uncertainties are noted in patient selection for surgical treatment of asymptomatic carotid stenosis and in optimal treatment targets for pharmacological therapies. Advanced imaging has been used to predict future risk of ipsilateral stroke and clarify mechanisms of actions of pharmacological therapies, primarily in observational studies.SummaryPharmacological and ...
Source: Current Cardiology Reports - October 1, 2021 Category: Cardiology Source Type: research

A Clinical Update on Antiplatelet Therapy in Secondary Prevention of Ischemic Stroke
AbstractPurpose of ReviewAntiplatelet therapy remains the standard of care in secondary stroke prevention for non-cardioembolic ischemic stroke and transient ischemic attack. We aim to examine the use of antiplatelet agents in secondary prevention through highlighting relevant clinical trials and meta-analyses as well as providing commentary regarding our practice.Recent FindingsIn the POINT and CHANCE trials, dual antiplatelet therapy reduced recurrent stroke compared to aspirin monotherapy. Sub-analyses of these trials suggest that genetic polymorphisms could play a role in diminishing the effectiveness of clopidogrel. S...
Source: Current Cardiology Reports - August 19, 2021 Category: Cardiology Source Type: research

Impact of Early Blood Pressure Lowering in Patients Presenting with Acute Ischemic Stroke
AbstractPurpose of ReviewIn this review article we will discuss the acute hypertensive response in the context of acute ischemic stroke and present the latest evidence-based concepts of the significance and management of the hemodynamic response in acute ischemic stroke.Recent FindingsAcute hypertensive response is considered a common hemodynamic physiologic response in the early setting of an acute ischemic stroke. The significance of the acute hypertensive response is not entirely well understood. However, in certain types of acute ischemic strokes, the systemic elevation of the blood pressure helps to maintain the colla...
Source: Current Cardiology Reports - May 7, 2021 Category: Cardiology Source Type: research

Stroke Rates Following Surgical Versus Percutaneous Revascularization for Ischemic Heart Disease
AbstractPurpose of ReviewCoronary revascularization is a commonly performed major procedure in the hospitals. Stroke is one of the dreaded complications after coronary revascularization procedures. The focus of this review is to understand the stroke risk in percutaneous cutaneous intervention (PCI) and coronary artery bypass grafting (CABG) procedures.Recent FindingsAvailable data show that PCI offers less procedural stroke risk compared to CABG although the survival benefits of CABG are better in certain scenarios. Innovative advancements in techniques, pre-procedural optimum medical therapy (OMT), intraoperative neuro-m...
Source: Current Cardiology Reports - March 15, 2021 Category: Cardiology Source Type: research

Permanent Bilateral Carotid Filters for Stroke Prevention in Atrial Fibrillation
AbstractPurpose of ReviewA novel permanent carotid filter device for percutaneous implantation was developed for the purpose of stroke prevention. In this review, we cover rationale, existing preclinical and clinical data, and potential future directions for research using such a device.Recent FindingsThe Vine ™ filter was assessed for safety in sheep and in 2 observational human studies, the completed CAPTURE 1 (n = 25) and the ongoing CAPTURE 2 (plannedn = 100). CAPTURE 1 has shown high procedural and long-term implant safety. A control group was not available for comparison.SummaryA mechanical filter for permanent str...
Source: Current Cardiology Reports - September 9, 2020 Category: Cardiology Source Type: research