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Condition: Ischemic Stroke
Drug: Phenobarbital
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Total 151 results found since Jan 2013.
Efficacy of the anti-seizure medications in acute symptomatic neonatal seizures caused by stroke. A systematic review
CONCLUSIONS: Our review shows that the use of ASMs that act throughout a gabaergic mechanism are inadequate in controlling seizures secondary to neonatal stroke in full-term newborns. Very effective seems to be lidocaine and levetiracetam with an apparent safer profile in short and long term. Bumetanide shows promising results, but they need to be confirmed by phase 3 studies.PMID:36533757 | PMC:PMC9828920 | DOI:10.23750/abm.v93i6.13440
Source: Acta Bio-Medica : Atenei Parmensis - December 19, 2022 Category: General Medicine Authors: Vincenzo Sortino Andrea Pratic ò Silvia Marino Roberta Criscione Martino Ruggieri Francesco Pisani Raffaele Falsaperla Source Type: research
Thromboembolic Risks with Concurrent Direct Oral Anticoagulants and Antiseizure Medications: A Population-Based Analysis
ConclusionsAlthough CYP/P-gp-modulating antiseizure medications were associated with an increased risk of ischemic stroke when paired with DOAC in the primary analysis, such a phenomenon was not found among patients with epilepsy who took phenytoin, valproate, or levetiracetam with DOAC. Therefore, these antiseizure medication options among patients with epilepsy with concurrent DOAC should not be restricted solely based on their potential drug –drug interactions. Yet, the increased mortality during concurrent use of DOAC with phenytoin or valproate might call for caution.
Source: CNS Drugs - November 24, 2022 Category: Neurology Source Type: research
