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Stroke in the Young: Etiologies and Risk Factors (P7.124)
CONCLUSIONS: Stroke in the young shares many of the same common modifiable risk factors as stroke in the elderly including hypertension, hyperlipidemia, diabetes, and tobacco abuse. Other unique disease processes also contribute to stroke in this age group, often less modifiable. Given the devastating morbidity and mortality of stroke in this age group, a larger public health effort for primary and secondary prevention of stroke in the young should be aggressively pursued.Disclosure: Dr. Govind has nothing to disclose. Dr. Ahad has nothing to disclose. Dr. Iftekhar has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Govind, P., Ahad, R., Iftekhar, A. Tags: Cerebrovascular Disease and Interventional Neurology: Stroke in Young Source Type: research

Relative Importance Of Stroke Sequelae According To Patients And Caregivers. (P7.160)
Conclusion: There is a greater concordance in rating the most important sequelae among patients and caregivers with left compared to right hemispheric stroke.Deficits in writing and empathy are underestimated as residual problems from stroke. Efforts to understand the causes and alleviate these problems are needed to improve QOL after stroke.Disclosure: Dr. Urrutia has received research support from Genentech Inc., and Lundbeck Research USA, Inc. Dr. Johnson has nothing to disclose. Dr. Hillis has received research support from Allon Pharmaceutical.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Urrutia, V., Johnson, B., Hillis, A. Tags: Cerebrovascular Disease and Interventional Neurology: Post-Stroke Function Source Type: research

Role of sleep-disordered breathing and sleep-wake disturbances for stroke and stroke recovery
Conclusions: SDB and SWD increase the risk of stroke in the general population and affect short- and long-term stroke recovery and outcome. Current knowledge supports the systematic implementation of clinical procedures for the diagnosis and treatment of poststroke SDB and SWD on stroke units.
Source: Neurology - September 25, 2016 Category: Neurology Authors: Hermann, D. M., Bassetti, C. L. Tags: All Cerebrovascular disease/Stroke, All Sleep Disorders, Other hypersomnias, Insomnia, Sleep apnea VIEWS AND REVIEWS Source Type: research

Probable REM sleep behavior disorder and risk of stroke: A prospective study
Conclusions: Presence of pRBD was associated with a higher risk of developing stroke, including both ischemic and hemorrhagic types. Future studies with clinically confirmed RBD and a longer follow-up would be appropriate to further investigate this association.
Source: Neurology - May 8, 2017 Category: Neurology Authors: Ma, C., Pavlova, M., Liu, Y., Liu, Y., Huangfu, C., Wu, S., Gao, X. Tags: All Cerebrovascular disease/Stroke, All Sleep Disorders, Cohort studies ARTICLE Source Type: research

Excessive Daytime Sleepiness and Depression in Stroke Survivors (P5.292)
Conclusions:The presence of EDS is associated with moderate to severe depression in stroke survivors. This is not related solely to SDB symptoms. Patients with fatigue and EDS should be screened for depression. Future studies are also needed to explore the role that SDB plays in this relationship.Disclosure: Dr. Pham has nothing to disclose. Dr. Sharrief has nothing to disclose. Dr. Savitz has received research support from the NIH. Dr. Sarraj has nothing to disclose. Dr. Fournier has nothing to disclose. Dr. Vahidy has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Pham, Q., Sharrief, A., Savitz, S., Sarraj, A., Fournier, L., Vahidy, F. Tags: Stroke Recovery and Rehabilitation Source Type: research

Sleep duration and risk of fatal and nonfatal stroke: A prospective study and meta-analysis
Conclusions: This prospective study and meta-analysis identified prolonged sleep as a potentially useful marker of increased future stroke risk in an apparently healthy aging population.
Source: Neurology - March 16, 2015 Category: Neurology Authors: Leng, Y., Cappuccio, F. P., Wainwright, N. W. J., Surtees, P. G., Luben, R., Brayne, C., Khaw, K.-T. Tags: All Cerebrovascular disease/Stroke, All Sleep Disorders, All epidemiology, Cohort studies, Incidence studies ARTICLE Source Type: research

Hypoglossal nerve dysfunction and sleep-disordered breathing after stroke
Conclusions: Acute ischemic stroke patients have a high prevalence of hypoglossal nerve dysfunction. Further studies are needed to explore whether hypoglossal nerve dysfunction may be a cause or consequence of SDB in stroke patients and whether this association can provide further insight into the pathophysiology of SDB in this population.
Source: Neurology - March 31, 2014 Category: Neurology Authors: Brown, D. L., Chervin, R. D., Wolfe, J., Hughes, R., Concannon, M., Lisabeth, L. D., Gruis, K. L. Tags: All Cerebrovascular disease/Stroke, Sleep apnea, All clinical neurophysiology, EMG ARTICLE Source Type: research

Feeding tube placement in stroke patients: Urgent need for health services and outcomes research
Up to 70% of acute stroke patients demonstrate dysphagia. Approximately half of these patients recover sufficient swallowing ability to meet their caloric needs, while the other half will have long-term swallowing dysfunction.1,2 Surgical feeding tubes can provide nutritional support in patients with severe dysphagia, but the decision of if and when to place a feeding tube poses a substantial challenge because of an inability to predict long-term recovery accurately. In this issue of Neurology®, George et al.3 examined feeding tube placement in the United States in adults with acute ischemic stroke. The authors used th...
Source: Neurology - September 1, 2014 Category: Neurology Authors: Willis, A. W., Williams, L., Mullen, M. T. Tags: All Health Services Research, Medical care, All Cerebrovascular disease/Stroke, All Sleep Disorders EDITORIALS Source Type: research

The association of sleep apnea and stroke with cognitive performance: the REasons for Geographic And Racial Differences in Stroke (REGARDS) Study (I9-4B)
CONCLUSIONS These results suggest that S+SA is associated with lower verbal memory and executive function scores (but not highest global cognitive impairment) than SA only, stroke only, or neither.Disclosure: Dr. Molano has nothing to disclose. Dr. Kleindorfer has received personal compensation for activities with Genentech. Dr. McClure has received research support from Genzyme and Amgen. Dr. Unverzagt has received personal compensation for activities with Eli Lilly & Company as a consultant. Dr. Wadley has received personal compensation for activities with Amgen Inc. Dr. Howard has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Molano, J., Kleindorfer, D., McClure, L., Unverzagt, F., Wadley, V., Howard, V. Tags: Treating Dementia in an Age of Mixed Disease Data Blitz Presentations Source Type: research

The association of sleep apnea and stroke with cognitive performance: the REasons for Geographic And Racial Differences in Stroke (REGARDS) Study (S53.005)
CONCLUSIONS These results suggest that S+SA is associated with lower verbal memory and executive function scores (but not highest global cognitive impairment) than SA only, stroke only, or neither.Disclosure: Dr. Molano has nothing to disclose. Dr. Kleindorfer has received personal compensation for activities with Genentech. Dr. McClure has received research support from Genzyme and Amgen. Dr. Unverzagt has received personal compensation for activities with Eli Lilly & Company as a consultant. Dr. Wadley has received personal compensation for activities with Amgen Inc. Dr. Howard has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Molano, J., Kleindorfer, D., McClure, L., Unverzagt, F., Wadley, V., Howard, V. Tags: Sleep Source Type: research

New Imaging-based definition of Stroke Boosts Annual Incidence of Recurrent Ischemic Stroke in the United States by 80percnt (P1.091)
CONCLUSIONS: Adopting a more expansive definition of stroke that incorporates presence of SBI would boost current estimates of the annual incidence of recurrent ischemic stroke in the US by approximately 80[percnt].Disclosure: Dr. Lin has nothing to disclose. Dr. Ovbiagele has nothing to disclose. Dr. Chui has received personal compensation in an editorial capacity for Archives of Neurology, Dr. Towfighi has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Lin, M., Ovbiagele, B., Chui, H., Towfighi, A. Tags: Neuroepidemiology: Cerebrovascular Disease, Critical Care, Epilepsy, Child Neurology, and Sleep Source Type: research

Stroke in a global world: geographical differences in stroke subtypes and age at onset in two different populations from Europe and South America. (P1.094)
CONCLUSIONS: Changes in the prevalence of vascular risk factors and stroke subtypes can be expected with the ageing of populations. In order to reduce age and stroke-related burden, public health strategies should be implemented. Study Supported by:Disclosure: Dr. Casanova-Lanchipa has nothing to disclose. Dr. Carod has received personal compensation for activities with Allergan, Merck Sharp & Dohme, Lundbeck Research USA, Inc., Biogen Idec, Esteve, and Pfizer as a scientific advisory board member and/or speaker. Dr. Cruz-Ramirez has nothing to disclose. Dr. Sanchez-Perez has nothing to disclose. Dr. Siacara-Aguayo has...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Casanova-Lanchipa, J., Carod, F., Cruz-Ramirez, L. M., Sanchez-Perez, N., Siacara-Aguayo, F., Gomez-Moreno, I., Gomez Romero, L., Coral, L., Trizotto, D., Moreira, C. Tags: Neuroepidemiology: Cerebrovascular Disease, Critical Care, Epilepsy, Child Neurology, and Sleep Source Type: research

Probable rapid eye movement sleep behavior disorder and risk of stroke: a prospective study (P4.302)
Conclusions:Presence of pRBD was associated with a higher risk of developing stroke, including both ischemic and hemorrhagic types. Future studies with clinically confirmed RBD and a longer follow-up would be appropriate to further investigate this association.Study Supported by: The National Institute of Neurological Disorders And Stroke at the National Institutes of Health (NINDS 5R21NS087235-02 to X.G.)Disclosure: Dr. Ma has nothing to disclose. Dr. Pavlova has received research support from Lundbeck and Biomobie Corporation. Dr. Liu has nothing to disclose. Dr. Liu has nothing to disclose. Dr. Huangfu has nothing to di...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Ma, C., Pavlova, M., Liu, Y., Liu, Y., Huangfu, C., Wu, S., Gao, X. Tags: Neuroepidemiology: Cerebrovascular Disease I Source Type: research

Differences in Ischaemic and Haemorrhagic Strokes in Sri Lanka: 7-year data from the Ragama Stroke Registry (P1.092)
CONCLUSIONS:Clinical and risk factor profiles were different between ICH and IS patients. Stroke severity and functional disability were higher among ICH patients. Study Supported by:Ragama Stroke Registry has been partly supported by research grants from the University of Kelaniya and Research Institute, International Medical Centre of Japan.Disclosure: Dr. Ranawaka has nothing to disclose. Dr. Peiris has nothing to disclose. Dr. Thirumavalavan has nothing to disclose. Dr. Premawansa has nothing to disclose. Dr. Kasthuriratne has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Ranawaka, U., Peiris, A., Thirumavalavan, K., Premawansa, G., Kasthuriratne, A. Tags: Neuroepidemiology: Cerebrovascular Disease, Critical Care, Epilepsy, Child Neurology, and Sleep Source Type: research

Author Response: Role Of Sleep-Disordered Breathing And Sleep-Wake Disturbances For Stroke And Stroke Recovery
Drs. Fuchs and Strasser raise the question of how the increased stroke incidence and disturbed stroke recovery that are observed both in patients with sleep-disordered breathing and sleep-wake disturbances are mediated. Increased stroke incidence may be due to excessive sympathetic activation that results in arterial hypertension, inflammation, and atherosclerosis.1 Conversely, disturbed stroke recovery and neuroplasticity might indeed result from disturbed tryptophan metabolism, as proposed by Drs. Fuchs and Strasser. Reduced formation of serotonin from tryptophan is well-known from inflammation-associated depression, whe...
Source: Neurology - January 8, 2017 Category: Neurology Authors: Hermann, D. M., Bassetti, C. L. Tags: WRITECLICK & amp;reg; EDITOR ' S CHOICE Source Type: research

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