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Source: Neurology
Condition: Diabetes

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Total 299 results found since Jan 2013.

Increased risk of stroke in patients with chronic kidney disease after recurrent hypoglycemia
Conclusions: CKD was associated with a higher risk of stroke and mortality in patients with hypoglycemia. Recurrent hypoglycemia considerably increased the risk of stroke and overall mortality in patients with CKD regardless of whether they had diabetes. These results suggest that hypoglycemia has a crucial role in stroke and death in patients with CKD.
Source: Neurology - August 18, 2014 Category: Neurology Authors: Yu, T.-M., Lin, C.-L., Chang, S.-N., Sung, F.-C., Kao, C.-H. Tags: Prognosis, All Cerebrovascular disease/Stroke, Cohort studies ARTICLE Source Type: research

Interleukin-6 and C-reactive protein as predictors of cognitive decline in late midlife
Conclusions: Elevated IL-6 but not CRP in midlife predicts cognitive decline; the combined cross-sectional and longitudinal effects over the 10-year observation period corresponded to an age effect of 3.9 years.
Source: Neurology - August 4, 2014 Category: Neurology Authors: Singh-Manoux, A., Dugravot, A., Brunner, E., Kumari, M., Shipley, M., Elbaz, A., Kivimaki, M. Tags: All Cognitive Disorders/Dementia, Cognitive aging, Risk factors in epidemiology ARTICLE Source Type: research

The global burden of neurologic diseases
WHO categorizes causes of death and disability into (1) communicable diseases, maternal and perinatal conditions, and nutritional deficiencies; (2) non-communicable diseases (NCD); and (3) injuries. NCD are the leading cause of death and disability globally and are rising as a result of demographic and epidemiologic changes occurring in both developed and developing countries.1,2 Increasing life expectancies, unhealthy diet, physical inactivity, tobacco use, and harmful use of alcohol contribute to the growing incidence and prevalence of NCD, such as heart disease, stroke, diabetes, cancers, and chronic respiratory disease...
Source: Neurology - July 21, 2014 Category: Neurology Authors: Chin, J. H., Vora, N. Tags: All Cerebrovascular disease/Stroke, All epidemiology, All Epilepsy/Seizures GLOBAL PERSPECTIVES Source Type: research

Herpes zoster as a risk factor for stroke and TIA: A retrospective cohort study in the UK
Conclusion: HZ is an independent risk factor for vascular disease in the UK population, particularly for stroke, TIA, and MI in subjects affected before the age of 40 years. In older subjects, better ascertainment of vascular risk factors and earlier intervention may explain the reduction in risk of stroke after HZ infection.
Source: Neurology - July 7, 2014 Category: Neurology Authors: Breuer, J., Pacou, M., Gautier, A., Brown, M. M. Tags: CORRECTED AND REPUBLISHED ARTICLES Source Type: research

Comment: Intracerebral hemorrhage incidence declines, but it is still highly fatal
Overall stroke mortality has declined over the last decades—a welcome trend.1 However, recent trends in intracerebral hemorrhage (ICH) incidence are not as clear. On the one hand, there has been increasingly good population control of hypertension; on the other hand, there is increasing use of anticoagulants and antithrombotic drugs, an epidemic of obesity and diabetes, and changing racial and ethnic demographics.
Source: Neurology - June 16, 2014 Category: Neurology Authors: Smith, E. E. Tags: Cohort studies, Incidence studies, Natural history studies (prognosis), Intracerebral hemorrhage ARTICLE Source Type: research

Multimorbidity and the risk of restless legs syndrome in 2 prospective cohort studies
Conclusions: Multimorbidity was a strong risk factor for RLS in these 2 population-based cohort studies. The results support the hypothesis that cumulative disease burden is more important than the presence of a specific single disease in the pathophysiology of RLS.
Source: Neurology - June 2, 2014 Category: Neurology Authors: Szentkiralyi, A., Volzke, H., Hoffmann, W., Trenkwalder, C., Berger, K. Tags: Restless legs syndrome, Cohort studies, Risk factors in epidemiology ARTICLE Source Type: research

Clinical Reasoning: Acute-onset homonymous hemianopia with hyperglycemia: Seeing is believing
A 32-year-old woman with a history of bipolar disorder, polycystic ovarian syndrome, and hypertension and a 4-year history of uncontrolled type 2 diabetes mellitus (DM) presented with bifrontal headache, elevated blood sugars (>500 mg/dL), and abrupt-onset left homonymous hemianopia upon awakening. Vital signs included temperature 98.0°F, blood pressure 160/89 mm Hg, and heart rate 67 bpm. Neurologic examination showed dense left homonymous hemianopia with macular sparing and without other focal findings.
Source: Neurology - April 14, 2014 Category: Neurology Authors: Strowd, R. E., Wabnitz, A., Balakrishnan, N., Craig, J., Tegeler, C. H. Tags: Endocrine, All Cerebrovascular disease/Stroke RESIDENT AND FELLOW SECTION Source Type: research

Impact of Stroke on A{beta}1-40 and A{beta}1-42 Plasmatic Levels (P1.105)
Conclusion. Aβ1-40 levels depend mainly on stroke characteristics, especially delay after onset, vascular risk factors and ischemic subtype, but not by PCoI. Aβ1-42 levels are not influenced by stroke, but their relationship with the cognitive status is more difficult to interpret.Disclosure: Dr. Moulin has nothing to disclose. Dr. Leys has received personal compensation in an editorial capacity for Lancet and Lancet Neurology. Dr. Leys has received research support from Bayer Pharmaceuticals Corp., Sanofi-Aventis Pharmaceuticals Inc., and Boehringer Ingelheim Pharmaceuticals Inc. Dr. Schraen-Maschke has nothing ...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Moulin, S., Leys, D., Schraen-Maschke, S., Bordet, R. Tags: Cerebrovascular Disease and Interventional Neurology: Translational Science Source Type: research

A Concentration Response Relationship between the Active Metabolite of Clopidogrel and Its Antiplatelet Activity (P1.106)
CONCLUSIONS: These findings could make it possible for clinicians to immediately tailor antiplatelet therapy to individual patients upon taking their first dose of clopidogrel, conceivably preventing a secondary event at a time when risk is the highest. Research is ongoing to explore whether disease states commonly seen in stroke patients, such as diabetes, change the amount of AM produced or whether they may actually result in a shift of the concentration response curve.Disclosure: Dr. Gengo has nothing to disclose. Dr. Wolff has nothing to disclose. Dr. Westphal has nothing to disclose. Dr. Rainka has nothing to disclose...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Gengo, F., Wolff, S., Westphal, E., Rainka, M., Bates, V. Tags: Cerebrovascular Disease and Interventional Neurology: Antiplatelet Agents and Miscellaneous Source Type: research

Primary Prevention of Stroke in Argentina: a Missed Opportunity? Data from the ARENAS Registry (P1.111)
CONCLUSIONS: this study provides data on stroke risk factors prevalence and control in an Argentine cohort. Our results show a high percentage of at-risk patients without adequate control in the primary prevention setting, denoting a missing opportunity to reduce the burden of stroke.Disclosure: Dr. Atallah has nothing to disclose. Dr. Fustinoni has nothing to disclose. Dr. Beigelman has nothing to disclose. Dr. Zurru has nothing to disclose. Dr. Ameriso has nothing to disclose. Dr. Cirio has nothing to disclose. Dr. Burry has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Atallah, A., Fustinoni, O., Beigelman, R., Zurru, M., Ameriso, S., Cirio, J., Burry, G. Tags: Cerebrovascular Disease and Interventional Neurology: Antiplatelet Agents and Miscellaneous Source Type: research

Hemorheology of Clinically Silent Multifocal Vascular Cerebral Lesions (P1.114)
CONCLUSIONS: We may suggest that a better red cell elasticity in patients results from a self-regulatory compensation. IgM molecules seem to play an opposite role to fibrinogen molecules in red cells aggregation phenomenon.Study Supported by: no supportedDisclosure: Dr. Kowal has nothing to disclose. Dr. Siemieniak has nothing to disclose. Dr. Marcinkowska-Gapinska has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Kowal, P., Siemieniak, I., Marcinkowska-Gapiłska, A. Tags: Cerebrovascular Disease and Interventional Neurology: Antiplatelet Agents and Miscellaneous Source Type: research

Stroke Risk Factors, Subtypes, and 30-Day Case Fatality in Abuja, Nigeria (P1.121)
CONCLUSIONS: Although hypertension, obesity, diabetes mellitus, and atrial fibrillation were important stroke risk factors, in many patients, these were detected only after a stroke. While the commonest stroke subtype was cerebral infarction, observed in almost two-third of patients, SAH was associated with the highest case-fatality rate at 30 days of 44.4%. Larger population-based studies are planned.Study Supported by: nilDisclosure: Dr. Bwala has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Bwala, S. Tags: Cerebrovascular Disease and Interventional Neurology: Ischemic Stroke Subtype Source Type: research

Cross-Border Acute Ischemic Stroke Subtype Comparison Between Hispanics and Mexican Mestizos (P1.123)
CONCLUSIONS: Small artery ischemic strokes were the most common subtype in both MM and Hispanic patients, and occurred with a similar frequency in the two populations. This similarity could be a consequence of a high pre-existing condition of hypertension in both groups. A higher incidence of large vessel and cardioembolic ischemic strokes were seen in MM compared with Hispanics, which may reflect the higher number of patients with risk factors of smoking and atrial fibrillation in the MM group.Disclosure: Dr. Cerdan-Trevino has nothing to disclose. Dr. Cantu-Martinez has nothing to disclose. Dr. Mora-Villalvazo has nothin...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Cerdan-Trevino, M., Cantu-Martinez, L., Mora-Villalvazo, R., Martinez, H., Hughes, R., Poisson, S. Tags: Cerebrovascular Disease and Interventional Neurology: Ischemic Stroke Subtype Source Type: research

Utility of Workup for Thrombophilias in a Single Center - A Qualitative Perspective (P1.125)
ConclusionStroke is considered cryptogenic in about 30-40 percent cases. Hypercoagulable testing is often ordered in this clinical setting. So far our results are consistent with other reports in the literature that such testing has limited clinical utility. Our results highlight the need to develop stringent clinical guidelines for HT in the setting of ischemic strokes.Disclosure: Dr. Shah has nothing to disclose. Dr. Anderson has nothing to disclose. Dr. Drake has received personal compensation for activities with UCB Pharma as a speaker. Dr. Proytcheva has nothing to disclose. Dr. Coull has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Shah, A., Anderson, N., Drake, K., Proytcheva, M., Coull, B. Tags: Cerebrovascular Disease and Interventional Neurology: Ischemic Stroke Subtype Source Type: research

Stroke And Cerebrovascular Risk Factors Knowledge In Patients Admitted To A Cardiovascular Ward. (P1.135)
Conclusion: Even in these selected population, with previous or current CVD, a large amount of RF and a high rate of previous medical consultations, knowledge about stroke showed to be very low indicating a poor quality of preventive measures and the need to emphasize educational interventions.Disclosure: Dr. Muñoz has nothing to disclose. Dr. Gonzalez Toledo has nothing to disclose. Dr. Pagani Cassara has nothing to disclose. Dr. Tamargo has nothing to disclose. Dr. Thomson has nothing to disclose. Dr. Nadile has nothing to disclose. Dr. Ferre has nothing to disclose. Dr. Klein has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Munoz Giacomelli, F., Gonzalez Toledo, M., Pagani Cassara, F., Tamargo, A., Thomson, A., Nadile, D., Ferre, A., Klein, F. Tags: Cerebrovascular Disease and Interventional Neurology: Atrial Fibrillation and Miscellaneous Source Type: research