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Source: Neurology
Condition: Diabetes

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Total 299 results found since Jan 2013.

Prehospital Initiation of Magnesium Sulfate in Patients with Acute Intracerebral Hemorrhage (S39.003)
Conclusions: Prehospital initiation permitted start of Mg therapy within the first 45 minutes of symptom onset in over half of patients, but did not alter rates of clinical deterioration in the first hours or disability at 3 months. Study Supported by NIH-NINDS Award U01 NS 44364Disclosure: Dr. Sanossian has received personal compensation for activities with Boehringer Ingelheim Pharmaceuticals, Inc. as a speakers bureau participant. Dr. Starkman has received research support from the National Institutes of Health, Lundbeck Research USA, Inc., Mitsubishi Tanabe Pharma, and Neurobiological Technologies, Inc. Dr. Liebeskind ...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Sanossian, N., Starkman, S., Liebeskind, D., Hamilton, S., Eckstein, M., Stratton, S., Pratt, F., Conwit, R., Sung, G., Saver, J. Tags: Cerebrovascular Disease and Interventional Neurology: Intracerebral Hemorrhage Source Type: research

Prevalence of Asymptomatic Cerebral Aneurysm in General population and Ischemic Stroke Patient (S47.007)
Conclusions: CA was more common in ischemic stroke patients than general population, especially in the 7th decade. Among the various vascular risk factors, hypertension was only correlated with increased prevalence of CA in ischemic stroke patients.Disclosure: Dr. Kim has nothing to disclose. Dr. Oh has nothing to disclose. Dr. Han has nothing to disclose. Dr. Lee has nothing to disclose. Dr. Lee has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Kim, J. H., Oh, Y.-J., Han, S. W., Lee, J. Y., Lee, K.-Y. Tags: Cerebrovascular Disease and Interventional Neurology Source Type: research

CARES (Changing and Advancing Risk factor control through Educations after Stroke): A Pilot Trial of a Transitions in Care Post-discharge Telephone Intervention for Stroke Patients (S13.006)
OBJECTIVE: The purpose of study is to test the feasibility and effectiveness of a telephonic post-discharge intervention designed to improve access to care, reinforce self-management skills, improve health literacy, and screen for complications in a government-run safety net system. BACKGROUND: In the United States, risk factor control after stroke is poor, particularly among socio-economically disadvantaged populations with poor access to care. The immediate post-discharge period is a vulnerable time for stroke patients, given their risk of recurrent stroke, worsening symptoms, complications, and need for medication titra...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Hudson, L., Corrales, M., Moreno, L., Valle, N., Razmara, A., Dutta, T., Ramirez-Gomez, L., Towfighi, A. Tags: Cerebrovascular Disease and Interventional Neurology: Epidemiology and Risk Factors Source Type: research

Racial differences in the Risk factors, Severity, Outcomes and Treatment in Acute Ischemic Stroke (P7.141)
Conclusion: Despite great disparity in both groups the outcomes were similar.Disclosure: Dr. Chauhan has nothing to disclose. Dr. Ali has nothing to disclose. Dr. Bianchi has nothing to disclose. Dr. Hinduja has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Chauhan, M. A., Ali, S., Bianchi, N., Hinduja, A. Tags: Cerebrovascular Disease and Interventional Neurology: Race, Ethnicity, and Stroke Source Type: research

An Association between Diabetes and Late Hospital Arrival among low-income Hispanic Stroke Patients (P7.144)
CONCLUSIONS: The presence of diabetes may be associated with delayed hospital arrival for acute stroke among low-income Hispanic stroke patients. Further studies are needed to confirm these findings.Disclosure: Dr. Ellyn has nothing to disclose. Dr. Williams has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Ellyn, L.-H., Williams, O. Tags: Cerebrovascular Disease and Interventional Neurology: Race, Ethnicity, and Stroke Source Type: research

Are there Different Rates of Acute Stroke Risk Factors in the South Texas Mexican American population? (P7.146)
CONCLUSION: In the South Texas Mexican American AIS population, there is greater then a three-fold higher prevalence of hypertension, diabetes and CHF compared with Hispanics/Latinos in the US. AFIB and CHF are significant predictors of poor outcome in this unique population.Disclosure: Dr. Tekle has nothing to disclose. Dr. Hassan has nothing to disclose. Dr. Malik has nothing to disclose. Dr. Jones-Fullingim has nothing to disclose. Dr. Sanchez has nothing to disclose. Dr. Jani has nothing to disclose. Dr. Sanchez has nothing to disclose. Dr. Abantao has nothing to disclose. Dr. Qureshi has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Tekle, W., Hassan, A., Malik, A., Jones-Fullingim, L., Sanchez, C., Jani, V., Sanchez, O., Abantao, E., Qureshi, A. Tags: Cerebrovascular Disease and Interventional Neurology: Race, Ethnicity, and Stroke Source Type: research

Clinical profile, risk factors, etiology and outcome of stroke in young Filipino adults. (P7.147)
Conclusion - Stroke occurs at a younger age in Filipinos compared to other Asian and European countries. The incidence of stroke in young Filipinos were similar to Asian figures but higher compared to European studies. Hypertension is the most common risk factor in the world followed by diabetes mellitus and dyslipidemia. In Filipinos however, cultural vices such as smoking and alcoholism were the second and third leading risk factors. This paper to the best of our knowledge is the first to report the unique profile of stroke in young Filipino patients.Disclosure: Dr. Talamera has nothing to disclose. Dr. San Jose has noth...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Talamera, T. A., San Jose, M. C., Sanchez, J. A., Pascual IV, J. L. Tags: Cerebrovascular Disease and Interventional Neurology: Race, Ethnicity, and Stroke Source Type: research

The association of sleep apnea and stroke with cognitive performance: the REasons for Geographic And Racial Differences in Stroke (REGARDS) Study (S53.005)
CONCLUSIONS These results suggest that S+SA is associated with lower verbal memory and executive function scores (but not highest global cognitive impairment) than SA only, stroke only, or neither.Disclosure: Dr. Molano has nothing to disclose. Dr. Kleindorfer has received personal compensation for activities with Genentech. Dr. McClure has received research support from Genzyme and Amgen. Dr. Unverzagt has received personal compensation for activities with Eli Lilly & Company as a consultant. Dr. Wadley has received personal compensation for activities with Amgen Inc. Dr. Howard has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Molano, J., Kleindorfer, D., McClure, L., Unverzagt, F., Wadley, V., Howard, V. Tags: Sleep Source Type: research

Glycated albumin predicts the effect of dual and single antiplatelet therapy on recurrent stroke
Conclusions: GA could be a potential biomarker to predict the effects of dual and single antiplatelet therapy in patients with minor stroke or TIA.
Source: Neurology - March 30, 2015 Category: Neurology Authors: Li, J., Wang, Y., Wang, D., Lin, J., Wang, A., Zhao, X., Liu, L., Wang, C., Wang, Y., On behalf of the CHANCE Investigators Tags: Other cerebrovascular disease/ Stroke, Prognosis, All Cerebrovascular disease/Stroke, Infarction ARTICLE Source Type: research

Leukoaraiosis and stroke recurrence risk in patients with and without atrial fibrillation
Conclusions: Leukoaraiosis is an independent predictor of stroke recurrence in non-AF stroke patients. However, leukoaraiosis did not increase the accuracy of the CHADS2 and CHA2DS2-VASc scores to predict stroke recurrence in AF or non-AF stroke patients.
Source: Neurology - March 23, 2015 Category: Neurology Authors: Ntaios, G., Lip, G. Y. H., Lambrou, D., Papavasileiou, V., Manios, E., Milionis, H., Spengos, K., Makaritsis, K., Vemmos, K. Tags: All Cerebrovascular disease/Stroke ARTICLE Source Type: research

Comment: The benefits of antiplatelets on stroke-- More arguments to keep patients adherent
The role of antiplatelet agents in stroke prevention is well documented, especially for secondary prevention, but many patients with no previous stroke but with other risk factors (high cardiovascular risk, women with diabetes mellitus, chronic kidney disease, peripheral artery disease, or asymptomatic carotid stenosis) can also benefit. The findings of Jung et al.1 are therefore clinically relevant and can be used to reassure patients that even if antiplatelet agents fail to prevent stroke, they can mitigate its severity. Although it is an observational study, a randomized trial to test the effect of antiplatelet agents o...
Source: Neurology - March 16, 2015 Category: Neurology Authors: Niewada, M. Tags: MRI, All Cerebrovascular disease/Stroke, Class II, Case control studies, Natural history studies (prognosis) ARTICLE Source Type: research

Effects of vascular risk factors and APOE {varepsilon}4 on white matter integrity and cognitive decline
Conclusions: Vascular risk factors are associated with reduced white matter integrity among older adults, which subsequently predicted faster cognitive decline. The detrimental effects of vascular risk factors on white matter microstructure were exacerbated among APOE 4 carriers.
Source: Neurology - March 16, 2015 Category: Neurology Authors: Wang, R., Fratiglioni, L., Laukka, E. J., Lovden, M., Kalpouzos, G., Keller, L., Graff, C., Salami, A., Backman, L., Qiu, C. Tags: MRI, Cognitive aging, Cohort studies, Risk factors in epidemiology ARTICLE Source Type: research

Long-term disability after lacunar stroke: Secondary prevention of small subcortical strokes
Conclusions: In lacunar stroke patients, older age was associated with worsening long-term disability, even without recurrence. Worse long-term function was associated with diabetes, cognitive status, and prior stroke, and regional differences may be attributable to variations in health care delivery or scale interpretation.
Source: Neurology - March 9, 2015 Category: Neurology Authors: Dhamoon, M. S., McClure, L. A., White, C. L., Lakshminarayan, K., Benavente, O. R., Elkind, M. S. V., On behalf of the SPS3 Investigators Tags: All Cerebrovascular disease/Stroke, All Rehabilitation, All epidemiology ARTICLE Source Type: research

Worsening risk factors and more strokes: The dark side of economic growth?
Stroke incidence has substantially decreased in developed countries.1 Health policies implemented in the 1970s to control hypertension, diabetes mellitus, and dyslipidemia, smoking cessation programs, and the use of oral anticoagulants in patients with atrial fibrillation have likely contributed to the decline in stroke incidence.1 By contrast, the landscape in rural China is rather bleak. In this issue of Neurology®, Wang et al.2 report increasing prevalence of vascular risk factors and incidence of first-ever stroke in a Chinese low-income rural population. Since China has experienced impressive development and given...
Source: Neurology - January 26, 2015 Category: Neurology Authors: Sposato, L. A. Tags: All Cerebrovascular disease/Stroke, Prevalence studies, Incidence studies, Natural history studies (prognosis), Risk factors in epidemiology EDITORIALS Source Type: research

Metabolomics predicts stroke recurrence after transient ischemic attack
Conclusions: The use of metabolomics in SR biomarker research improves the predictive power of conventional predictors such as ABCD2 and LAA. Moreover, pattern recognition methods allow us to discriminate not only SR patients but also early and late SR cases.
Source: Neurology - December 29, 2014 Category: Neurology Authors: Jove, M., Mauri-Capdevila, G., Suarez, I., Cambray, S., Sanahuja, J., Quilez, A., Farre, J., Benabdelhak, I., Pamplona, R., Portero-Otin, M., Purroy, F. Tags: All Cerebrovascular disease/Stroke ARTICLE Source Type: research