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TALOS: a multicenter, randomized, double‐blind, placebo‐controlled trial to test the effects of citalopram in patients with acute stroke
DiscussionSSRI treatment is well tolerated and overall beneficial in the wake of stroke; it may also be neuroprotective and prevent new vascular events.
Source: International Journal of Stroke - April 8, 2015 Category: Neurology Authors: Kristian Lundsgaard Kraglund, Janne Kaergaard Mortensen, Erik Lerkevang Grove, Søren Paaske Johnsen, Grethe Andersen Tags: Protocol Source Type: research

Circadian sleep/wake rhythm abnormalities as a risk factor of a poststroke apathy
ConclusionThese results indicate that early poststroke alterations of sleep/wake circadian rhythms – easily evaluated by actigraphy – are associated with a higher risk of poststroke apathy at three‐months. In terms of clinical outcomes, our results provide targets for very early identification of patients at risk to develop apathy after stroke and for assessing when to start specific therapy to optimize rehabilitation efficiency.
Source: International Journal of Stroke - December 25, 2014 Category: Neurology Authors: Charlotte Cosin, Igor Sibon, Mathilde Poli, Michèle Allard, Sabrina Debruxelles, Pauline Renou, François Rouanet, Willy Mayo Tags: Research Source Type: research

Poststroke fatigue: risk factors and its effect on functional status and health‐related quality of life
ConclusionDepressive symptoms and prestroke fatigue are major correlates of poststroke fatigue while more severe poststroke fatigue is associated with poorer activities of daily living and health‐related quality of life.
Source: International Journal of Stroke - December 3, 2014 Category: Neurology Authors: Yang‐Kun Chen, Jian‐Feng Qu, Wei‐Min Xiao, Wan‐Yi Li, Han‐Yu Weng, Wei Li, Yong‐Lin Liu, Gen‐Pei Luo, Xue‐Wen Fang, Gabor S. Ungvari, Yu‐Tao Xiang Tags: Research Source Type: research

Depression: Cognition relations after stroke
ConclusionsThe rates of depression and cognitive impairment were in the range of previous stroke studies. Our study suggested a strong relation between depression and cognition characterized by executive functions and working memory dysfunctioning.
Source: International Journal of Stroke - October 1, 2013 Category: Neurology Authors: Marc Hommel, Leeanne Carey, Assia Jaillard Tags: Short report Source Type: research