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Priorities for Comparative Effectiveness Reviews in Cardiovascular Disease Original Articles
Conclusions— Using a systematic process deriving consensus from multiple stakeholders across cardiovascular disease states, we generated a prioritized list of evidence synthesis topics to inform decision makers. The topics vetted through this process seek to determine the comparative safety and effectiveness of a range of treatments, both established and emerging, and are immediately relevant for prevalent disease states.
Source: Circulation: Cardiovascular Quality and Outcomes - March 19, 2013 Category: Cardiology Authors: Eapen, Z. J., McBroom, A. J., Gray, R., Musty, M. D., Hadley, C., Hernandez, A. F., Sanders, G. D. Tags: Health policy and outcome research, Congestive, Cerebrovascular disease/stroke, Acute coronary syndromes, Arrhythmias, clinical electrophysiology, drugs Original Articles Source Type: research

Abstract 15: Decisional Needs in Patients Considering Left Ventricular Assist Device as Destination Therapy: Contrast Between Acceptors and Decliners Concurrent Session I Session C: Young Investigator Award Finalists Oral Abstract Presentations
Conclusions: There is a fundamental difference in values surrounding death among patients who either accept or decline a DT LVAD. Decision support interventions around this complex medical decision need to consider patient values first before getting into more cognitive aspects of the decision making process.
Source: Circulation: Cardiovascular Quality and Outcomes - May 15, 2013 Category: Cardiology Authors: McIlvennan, C. K., Allen, L. A., Nowels, C., Cleveland, J. C., Brieke, A., Matlock, D. D. Tags: Concurrent Session I Session C: Young Investigator Award Finalists Oral Abstract Presentations Source Type: research

Abstract 53: Health Care Utilization and Cost among Type 2 Diabetes Mellitus (T2DM) Patients with Cardiovascular Disease (CVD) or Cardiovascular Disease Risk Factors Poster Session I
CV events among T2DM patients are major contributors to high healthcare utilization and cost. Healthcare utilization and costs among T2DM patients with established CVD and CVD risk factors in a large US database were explored.T2DM patients aged ≥40 years were identified from the HealthCore Integrated Research Environment from 1/1/2007 to 4/30/2011 and followed from first T2DM diagnosis (index date) until loss of eligibility or death. Established CVD [Group 1] included patients with MI, stroke, peripheral vascular disease, coronary heart disease, congestive heart failure, or revascularization in the year prior to index. ...
Source: Circulation: Cardiovascular Quality and Outcomes - May 15, 2013 Category: Cardiology Authors: Kern, D. M., DeVore, S., Kim, J., Wu, Y., Tunceli, O., Wu, B., Hirshberg, B. Tags: Poster Session I Source Type: research

Abstract 63: The Smoking Paradox in Patients Hospitalized with Coronary Artery Disease: Findings from Get With The Guidelines - CAD Poster Session I
Conclusion: Smoking continues to be a major risk factor for presenting with CAD at a much younger age and with fewer risk factors. It is likely that the continued modest association with lower in-hospital mortality in smokers in this analysis after adjustment reflects residual or unmeasured confounding. This apparent smoker’s paradox in CAD should not be interpreted as a benefit of cigarette smoking.
Source: Circulation: Cardiovascular Quality and Outcomes - May 15, 2013 Category: Cardiology Authors: Ali, S. F., Smith, E. E., Bhatt, D. L., Pan, W., Fonarow, G. C., Schwamm, L. H. Tags: Poster Session I Source Type: research

Abstract 96: Sex Differences in Pre-Event Health Status of Young Patients with Acute Myocardial Infarction: The VIRGO Study Poster Session I
Conclusion: Compared with men, young women presenting with an AMI seem to have worse health status with poorer physical functioning and quality of life prior to their event. In light of these findings, it may be useful for healthcare providers to identify young women who are at increased cardiovascular risk at an earlier stage in order to optimize their health status.
Source: Circulation: Cardiovascular Quality and Outcomes - May 15, 2013 Category: Cardiology Authors: Dreyer, R. P., Smolderen, K. G., Strait, K. M., Beltrame, J. F., Lichtman, J. H., Lorenze, N. P., D'Onofrio, G., Krumholz, H. M., Spertus, J. A. Tags: Poster Session I Source Type: research

Abstract 150: Resource Utilization Patterns and Outcomes Among Acute Coronary Syndrome Patients: Findings From a Multi-Payer Analysis Poster Session II
Conclusion: These findings suggest that many patients with ACS do not receive appropriate recommended antithrombotic prophylaxis, and opportunities exist to improve therapy. Increased use of software tools such as AQuA may support enhanced education efforts aimed at improving adherence to guidelines and quality of care.
Source: Circulation: Cardiovascular Quality and Outcomes - May 15, 2013 Category: Cardiology Authors: Lang, K., Bozkaya, D., Patel, A. A., Macomson, B., Crivera, C., Owens, G., Mody, S. Tags: Poster Session II Source Type: research

Abstract 205: New Onset Heart Failure and Adverse Ischemic Events Associated with Amiodarone and Dronedarone Use among Atrial Fibrillation Patients Poster Session II
Conclusions: In a propensity score matched observational cohort study, amiodarone use was associated with higher incidence rate of new onset HF, HF hospitalizations, and TIA as identified from claims. This finding differs from other clinical studies. Future observational cohort studies should incorporate medical record review for validation since information from claims might be insufficient to fully account for underlying patient risk status, or accurately determine if HF was new onset.Key words: amiodarone; dronedarone; atrial fibrillation; heart failure.
Source: Circulation: Cardiovascular Quality and Outcomes - May 15, 2013 Category: Cardiology Authors: Sylwestrzak, G., Liu, J., Rosenberg, A., White, J., Barron, J., Redberg, R., Malenka, D. Tags: Poster Session II Source Type: research

Abstract 227: Prescribing Warfarin at Discharge for Heart Failure Patients without Atrial Fibrillation Findings from the Get With The Guidelines-Heart Failure Registry Poster Session II
Conclusions: Approximately 1 in 10 HF patients without AF or other documented indications are prescribed warfarin at discharge, and prescription rates vary widely across hospitals. Further research is needed to understand why anticoagulation is prescribed to patients with HF in the absence of documented indications.
Source: Circulation: Cardiovascular Quality and Outcomes - May 15, 2013 Category: Cardiology Authors: Eapen, Z., Grau-Sepulveda, M., Fonarow, G., Heidenreich, P., Peterson, E., Hernandez, A. Tags: Poster Session II Source Type: research

Abstract 251: Risk Factors for Recurrence of Cardiovascular Events Following Acute Coronary Syndrome: Longitudinal Analysis from 2006-2011 Poster Session III
Conclusion: Following an ACS event, patients with pre-admission statin use or a prior CABG had decreased risk, while older patients or those with baseline comorbidities had increased risk of an adverse CV event occurring sooner. Ultimately, identifying high-risk ACS subgroups may facilitate tailored and more aggressive treatment to improve outcomes.
Source: Circulation: Cardiovascular Quality and Outcomes - May 15, 2013 Category: Cardiology Authors: Reddy, V. S., Luthra, R., Xu, Y., Wilhelm, K., Power, T. P., Fisher, M. D., Cziraky, M. J. Tags: Poster Session III Source Type: research

Abstract 20: Public Reporting of Mortality Rates for Cardiovascular Conditions Did Not Improve Patient Outcomes Session Title: Concurrent II Session A: Oral Abstracts on Policy Issues
Conclusions: We found that mortality rates for publicly reported conditions were improving slightly during the period when only processes of care were being reported, but that these improvements slowed or reversed once public reporting of mortality rates began. These findings suggest that public reporting may be necessary, but is clearly not sufficient, to improve patient outcomes.
Source: Circulation: Cardiovascular Quality and Outcomes - June 2, 2014 Category: Cardiology Authors: Joynt, K. E., Orav, E. J., Jha, A. K. Tags: Session Title: Concurrent II Session A: Oral Abstracts on Policy Issues Source Type: research

Abstract 110: Long-Term Health Status Outcomes in Young Women with Acute Myocardial Infarction: Results from the VIRGO Study Session Title: Poster Session I
Conclusion: Compared with men, young women are more likely to have "poor" health status outcomes after AMI. This information is critically important in developing targets for gender-specific interventions to improve young women’s recovery post AMI.
Source: Circulation: Cardiovascular Quality and Outcomes - June 2, 2014 Category: Cardiology Authors: Dreyer, R. P., Strait, K. M., Lichtman, J. H., Lorenze, N., D'Onofrio, G., Bueno, H., Spertus, J. A., Krumholz, H. M. Tags: Session Title: Poster Session I Source Type: research

Abstract 125: Clinical Outcomes Following Continuous-Flow Left Ventricular Assist Device: A Systematic Review Session Title: Poster Session I
Conclusion: The totality of data for CF LVADs show consistent improvements in survival and quality of life counterbalanced by a range of common complications. While this summary should provide a practical resource for health care provider-led discussions with patients, it highlights the critical need for high-quality patient-centered data collected with standard definitions.
Source: Circulation: Cardiovascular Quality and Outcomes - June 2, 2014 Category: Cardiology Authors: McIlvennan, C. K., Magid, K. H., Ambardekar, A. V., Thompson, J. S., Matlock, D. D., Allen, L. A. Tags: Session Title: Poster Session I Source Type: research

Abstract 161: Atrial Fibrillation in India: Insights from the PINNACLE India Outpatient Registry Session Title: Poster Session I
Conclusion: AF is tough to diagnose since it is often asymptomatic and clinicians need many tests to confirm diagnosis. Lack of documentation or detection of AF and its associated conditions is a concern. AF can lead to life threatening problems such as stroke and heart failure. The surveillance of AF in India is important in order to identify opportunities for intervention. Continued data collection through the use of a cardiovascular registry can improve the understanding of AF in India.
Source: Circulation: Cardiovascular Quality and Outcomes - June 2, 2014 Category: Cardiology Authors: Glusenkamp, N. T., Risch, S. A., Kerkar, P., Kumar, G., Oetgen, W. J. Tags: Session Title: Poster Session I Source Type: research

Abstract 172: Patients' Experiences from Symptom Onset to Initial Treatment for Atrial Fibrillation Session Title: Poster Session I
Conclusions: Providers’ played a critical role in reducing patients' emotional distress and helping them to develop an accurate understanding of AF symptoms and treatment. This study provides new insight into participant experiences from symptom onset through initial treatment of AF which may inform development of patient centered interventions to promote early effective AF self-management.
Source: Circulation: Cardiovascular Quality and Outcomes - June 2, 2014 Category: Cardiology Authors: McCabe, P. J., Rhudy, L., DeVon, H. Tags: Session Title: Poster Session I Source Type: research

Abstract 178: Females with Cardiac Comorbidities Have Worse Outcome Compared to Males Presenting with Unexplained Syncope: An ACAP-SELF Dataset Analysis Session Title: Poster Session I
Conclusions: The SELF-pathway for patients with syncope helps identify at-risk subgroups in our patient population. Females with SELF-2 criteria (Structural heart disease, abnormal ECG, arrhythmia) had significantly worse long-term outcome compared to males regardless of manner of syncopal presentation.
Source: Circulation: Cardiovascular Quality and Outcomes - June 2, 2014 Category: Cardiology Authors: Pratap, B., Bastawrose, J., Gurram, A., Panneerselvam, N., Lingannan, A., Kalamkar, P., Patel, D., Verzosa, J., Shahanoor, Z., Umali, T., Pamidimukala, C., Pierce, M., Aziz, E. F., Herzog, E. Tags: Session Title: Poster Session I Source Type: research

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