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Treatment of complex coronary artery disease in patients with diabetes: 5-year results comparing outcomes of bypass surgery and percutaneous coronary intervention in the SYNTAX trial ADULT CARDIAC
CONCLUSIONS In both diabetic and non-diabetic patients, PCI resulted in higher rates of MACCE and repeat revascularization at 5 years. Although PCI is a potential treatment option in patients with less-complex lesions, CABG should be the revascularization option of choice for patients with more-complex anatomic disease, especially with concurrent diabetes.
Source: European Journal of Cardio-Thoracic Surgery - April 8, 2013 Category: Cardiovascular & Thoracic Surgery Authors: Kappetein, A. P., Head, S. J., Morice, M.-C., Banning, A. P., Serruys, P. W., Mohr, F.-W., Dawkins, K. D., Mack, M. J., on behalf of the SYNTAX Investigators Tags: ADULT CARDIAC Source Type: research

The association between platelet transfusion and adverse outcomes after coronary artery bypass surgery ADULT CARDIAC
CONCLUSIONS Platelet transfusion at the time of CABG is not associated with increased postoperative mortality, in-hospital myocardial infarction, stroke or need for repeat coronary revascularization.
Source: European Journal of Cardio-Thoracic Surgery - October 16, 2015 Category: Cardiovascular & Thoracic Surgery Authors: Kremke, M., Hansen, M. K., Christensen, S., Tang, M., Andreasen, J. J., Jakobsen, C.-J. Tags: Cardiac - physiology, Extracorporeal circulation, Molecular biology ADULT CARDIAC Source Type: research

On-pump versus off-pump coronary artery bypass graft surgery among patients with type 2 diabetes in the Bypass Angioplasty Revascularization Investigation 2 Diabetes trial ADULT CARDIAC
CONCLUSIONS Patients with diabetes had greater risk of major cardiovascular events long-term after off-pump CABG than after on-pump CABG.
Source: European Journal of Cardio-Thoracic Surgery - January 13, 2016 Category: Cardiovascular & Thoracic Surgery Authors: Singh, A., Schaff, H. V., Mori Brooks, M., Hlatky, M. A., Wisniewski, S. R., Frye, R. L., Sako, E. Y., on behalf of the BARI 2D Study Group Tags: Electrophysiology - arrhythmias, Molecular biology ADULT CARDIAC Source Type: research

Open aortic arch replacement in high-risk patients: the gold standard AORTIC SURGERY
CONCLUSIONS Open TAR can be performed with low mortality and morbidity and excellent long-term results even in high-risk patients. Total endovascular repair may represent an option for patients not suitable for open surgery.
Source: European Journal of Cardio-Thoracic Surgery - January 13, 2016 Category: Cardiovascular & Thoracic Surgery Authors: Iafrancesco, M., Ranasinghe, A. M., Dronavalli, V., Adam, D. J., Claridge, M. W., Riley, P., McCafferty, I., Mascaro, J. G. Tags: Pericardium AORTIC SURGERY Source Type: research

Coronary artery bypass grafting vs percutaneous coronary intervention in a 'real-world' setting: a comparative effectiveness study based on propensity score-matched cohorts ADULT CARDIAC
CONCLUSIONS In the ‘real-world’ setting of this study, CABG was associated with significantly lower rates of death, MI and TVR in patients with LMCA or multivessel disease, so it remains the standard of care, particularly for patients with more extensive coronary disease and diabetes.
Source: European Journal of Cardio-Thoracic Surgery - June 13, 2013 Category: Cardiovascular & Thoracic Surgery Authors: Fortuna, D., Nicolini, F., Guastaroba, P., De Palma, R., Di Bartolomeo, S., Saia, F., Pacini, D., Grilli, R., on behalf of RERIC (Regional Registry of Cardiac Surgery), REAL (Regional Registry of Coronary Angioplasties) Investigators Tags: ADULT CARDIAC Source Type: research

Minimally invasive direct coronary bypass grafting versus percutaneous coronary intervention for single-vessel disease: a meta-analysis of 2885 patients REVIEWS
In conclusion, the present systematic review underscores the superiority of MIDCAB over PCI for treatment of single-vessel disease of the LAD.
Source: European Journal of Cardio-Thoracic Surgery - February 11, 2015 Category: Cardiovascular & Thoracic Surgery Authors: Deppe, A.-C., Liakopoulos, O. J., Kuhn, E. W., Slottosch, I., Scherner, M., Choi, Y.-H., Rahmanian, P. B., Wahlers, T. Tags: Coronary disease REVIEWS Source Type: research

Differences in baseline characteristics, practice patterns and clinical outcomes in contemporary coronary artery bypass grafting in the United States and Europe: insights from the SYNTAX randomized trial and registry ADULT CARDIAC
CONCLUSIONS Repeat revascularization rates following CABG in the USA versus Europe were increased at 5 years, particularly in off-pump patients. There was no significant difference in the rate of death, stroke and MI.
Source: European Journal of Cardio-Thoracic Surgery - March 13, 2015 Category: Cardiovascular & Thoracic Surgery Authors: Head, S. J., Parasca, C. A., Mack, M. J., Mohr, F. W., Morice, M.-C., Holmes, D. R., Feldman, T. E., Dawkins, K. D., Colombo, A., Serruys, P. W., Kappetein, A. P., for the SYNTAX Investigators Tags: Molecular biology ADULT CARDIAC Source Type: research

Bilateral internal thoracic artery grafting increases long-term survival in elderly patients ADULT CARDIAC
CONCLUSIONS The use of BITA grafting in elderly patients improves the 10-year survival rate, with similar postoperative morbidity. Thus, using adequate selection criteria, this technique should be routinely extended also to patients older than 70 years.
Source: European Journal of Cardio-Thoracic Surgery - March 13, 2015 Category: Cardiovascular & Thoracic Surgery Authors: Pettinari, M., Sergeant, P., Meuris, B. Tags: Molecular biology ADULT CARDIAC Source Type: research

Effects of on-pump and off-pump surgery in the Arterial Revascularization Trial ADULT CARDIAC
CONCLUSIONS The outcomes of contemporary CABG are excellent with low mortality, stroke, myocardial infarction and need for wound reconstruction and repeat revascularization whether performed on-pump or off-pump. CLINICAL TRIAL REGISTRATION Controlled-trials.com (ISRCTN46552265).
Source: European Journal of Cardio-Thoracic Surgery - May 19, 2015 Category: Cardiovascular & Thoracic Surgery Authors: Taggart, D. P., Altman, D. G., Gray, A. M., Lees, B., Nugara, F., Yu, L.-M., Flather, M., on behalf of the ART Investigators Tags: Electrophysiology - arrhythmias, Molecular biology ADULT CARDIAC Source Type: research

Safety and efficacy of miniaturized extracorporeal circulation when compared with off-pump and conventional coronary artery bypass grafting: evidence synthesis from a comprehensive Bayesian-framework network meta-analysis of 134 randomized controlled trials involving 22 778 patients ADULT CARDIAC
CONCLUSIONS MECC and OPCAB both improve perioperative outcomes following coronary bypass surgery when compared with conventional CABG performed with extracorporeal circulation. MECC may represent an attractive compromise between OPCAB and CECC.
Source: European Journal of Cardio-Thoracic Surgery - April 28, 2016 Category: Cardiovascular & Thoracic Surgery Authors: Kowalewski, M., Pawliszak, W., Raffa, G. M., Malvindi, P. G., Kowalkowska, M. E., Zaborowska, K., Kowalewski, J., Tarelli, G., Taggart, D. P., Anisimowicz, L. Tags: Molecular biology, History, Myocardial protection, Peripheral vascular, Transplantation - heart ADULT CARDIAC Source Type: research

Comparison between off- and on-pump coronary artery bypass grafting: long-term results of a real-world registry ADULT CARDIAC
CONCLUSIONS In patients undergoing elective isolated CABG, on-pump strategy conferred a long-term survival advantage compared with off-pump strategy, particularly for patients with more extensive coronary disease. No benefits were found in terms of reduction of postoperative morbidity with the off-pump strategy. On-pump surgery should be the preferred revascularization technique, and off-pump surgery reserved for patients for whom the perioperative risk of cardiopulmonary bypass is greater than the risk of a less complete coronary revascularization.
Source: European Journal of Cardio-Thoracic Surgery - August 30, 2016 Category: Cardiovascular & Thoracic Surgery Authors: Nicolini, F., Fortuna, D., Contini, G. A., Pacini, D., Gabbieri, D., Zussa, C., De Palma, R., Vezzani, A., Gherli, T., on behalf of the RERIC (Registro dell'Emilia Romagna degli Interventi Cardiochirurgici) Investigators Tags: Molecular biology ADULT CARDIAC Source Type: research

Effect of preoperative angiotensin-converting enzyme inhibitor on the outcome of coronary artery bypass graft surgery REVIEWS
The safety of the preoperative administration of angiotensin-converting enzyme inhibitors (ACEIs) in patients undergoing coronary artery bypass grafting (CABG) surgery is still uncertain. This systematic review thus evaluated the effect of preoperative ACEIs on the clinical outcomes in patients undergoing CABG surgery. We searched PubMed, the Cochrane Library and the Web of Science for randomized control trials or observational studies that compared the use of ACEIs with that of placebos before isolated CABG. Thirteen studies (3 randomized control trials and 10 observational studies) that included 31 390 patients met the e...
Source: European Journal of Cardio-Thoracic Surgery - April 9, 2015 Category: Cardiovascular & Thoracic Surgery Authors: Zhang, Y., Ma, L. Tags: Molecular biology REVIEWS Source Type: research

Outcome of total arch replacement with coronary artery bypass grafting AORTIC SURGERY
CONCLUSIONS Although concomitant CABG in TAR patients had higher operative risk, it can be safely performed with favourable outcomes.
Source: European Journal of Cardio-Thoracic Surgery - May 19, 2015 Category: Cardiovascular & Thoracic Surgery Authors: Takashima, N., Suzuki, T., Asai, T., Nota, H., Ikegami, H., Kinoshita, T., Fujino, S., Hosoba, S. Tags: Molecular biology, Pericardium AORTIC SURGERY Source Type: research

New-onset atrial fibrillation at discharge in patients after coronary artery bypass surgery: short- and long-term morbidity and mortality ADULT CARDIAC
CONCLUSIONS A majority of NOAF patients revert to SR during the first months after surgery. On the other hand, 20–25% of NOAF patients develop chronic AF during long-term follow-up. Almost half of the NOAF patients were hospitalized during follow-up due to cardiovascular causes. Similarly, NOAF was associated with increased mortality due to cardiac causes, but not increased risk of stroke. This highlights the need for proper oral anticoagulation therapy in these patients.
Source: European Journal of Cardio-Thoracic Surgery - October 16, 2015 Category: Cardiovascular & Thoracic Surgery Authors: Tulla, H., Hippelainen, M., Turpeinen, A., Pitkanen, O., Hartikainen, J. Tags: Molecular biology, Myocardial infarction ADULT CARDIAC Source Type: research

Coronary artery bypass surgery without cardioplegia: hospital results in 8515 patients ADULT CARDIAC
CONCLUSIONS Isolated CABG with CPB using non-cardioplegic methods proved very safe, with low mortality and morbidity. These methods are simple and expeditious and remain as very useful alternative techniques of myocardial preservation.
Source: European Journal of Cardio-Thoracic Surgery - February 6, 2016 Category: Cardiovascular & Thoracic Surgery Authors: Antunes, P. E., Ferrao de Oliveira, J., Prieto, D., Coutinho, G. F., Correia, P., Branco, C. F., Antunes, M. J. Tags: Molecular biology ADULT CARDIAC Source Type: research

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