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Harmonizing Together: Speech and Music Therapy and Support for Patients and Partners with PPA (P5.157)
Conclusions:The reports of improvement in caregiver health, social participation of patients, and functional communication are in line with the group’s focus and goals. In contrast, more comprehensive knowledge of the disease process may have led patients and caregivers to experience greater feelings of guilt and fear. Our qualitative observations and reports from participants indicated that the most beneficial parts of the group were raising patients’ confidence in communication and allowing both patients and families suffering from PPA to connect with one another.Study Supported by:Funding NIH grant NS077059;...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Quimby, M., Shaprio-Gordon, J., Brandt, K., Hyatt, C., Grimm, M., Richardson, L., Howland, K., Dickerson, B. Tags: Clinical Neuro-rehabilitation Source Type: research

Elevated cerebrospinal fluid total Tau levels reflects predominant cortical involvement in Alzheimers disease (P1.093)
Conclusions:Elevated CSF Tau levels in AD patients could be surrogate biomarker for AD subtypes with predominant early cortical symptoms and atrophy. There is a need for a systematic prospective unbiased follow-up to see if rapid clinical progression in AD is related to elevated T-Tau and distinct AD subtypes.Disclosure: Dr. Pillai has nothing to disclose. Dr. Khrestian has nothing to disclose. Dr. Bekris has nothing to disclose. Dr. Safar has nothing to disclose. Dr. Leverenz has received personal compensation for activities with Axovant, GE Healthcare and Navidea Biopharmaceuticals as a consultant.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Pillai, J., Khrestian, M., Bekris, L., Safar, J., Leverenz, J. Tags: Aging and Dementia: Biomarkers Source Type: research

Factors Associated with Follow-Up in Stroke Clinic after Hospital Discharge (P2.323)
Conclusions: Stroke clinic follow-up is best achieved in patients admitted to the neurology service. Ensuring standardized discharge instructions with provided time and date of outpatient appointment is the key for successful follow-up.Disclosure: Dr. Bakradze has nothing to disclose. Dr. Taboada has nothing to disclose. Dr. Narwal has nothing to disclose. Dr. Nouh has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Bakradze, E., Taboada, S., Narwal, P., Nouh, A. Tags: Stroke Systems of Care Source Type: research

Network dysfunction predicts speech production after left hemisphere stroke
Conclusions: Speech production is dependent on complex interactions among widely distributed brain networks, indicating that residual speech production after stroke depends on more than the restoration of local domain-specific functions. Our understanding of the recovery of function following focal lesions is not adequately captured by consideration of ipsilesional or contralesional brain regions taking over lost domain-specific functions, but is perhaps best considered as the interaction between what remains of domain-specific networks and domain-general systems that regulate behavior.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Geranmayeh, F., Leech, R., Wise, R. J. S. Tags: All Cerebrovascular disease/Stroke, Aphasia ARTICLE Source Type: research

Formal Education, Socioeconomic Status and Severity of Neglect (P1.119)
Conclusions: These findings suggest that higher years of education do not decrease the severity of neglect in patients after stroke involving the non-dominant hemisphere. Unlike language disorders, neglect does not seem to be affected by education level. Patients from higher SES class showed less severe neglect; further research is needed to determine if this can be explained by differences in stroke characteristics, brain characteristics (e.g. leukoareosis), or interventions.Disclosure: Dr. Kharal has nothing to disclose. Dr. Suneja has nothing to disclose. Dr. Hillis received personal compensation in an editorial capacit...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Kharal, A., Suneja, A., Hillis, A. Tags: Cerebrovascular Disease: Epidemiology Source Type: research

Acute Stroke Code Accuracy in the Inpatient Versus Emergency Department (ED) Setting (S16.003)
Conclusion FP were more common for inpatient versus ED codes AMS or SS were infrequently associated with stroke diagnosis. Better education for non-neuroscience hospital providers, regarding acute stroke criteria, is needed.Disclosure: Dr. Schneck has received research support from NIH (POINT, COSS, ARUBA, ALIAS, Lundbeck (DIAS4), TIMI-50 Consortium, and Local PI Multicenter Clincial trials. Dr. Bruzzone has nothing to disclose. Dr. Vlahovic has nothing to disclose. Dr. Durazo-Arvizu has nothing to disclose. Dr. Biller has received personal compensation in an editorial capacity for the Journal of Stroke and Cerebrovascular...
Source: Neurology - February 7, 2016 Category: Neurology Authors: Schneck, M., Bruzzone, M., Vlahovic, L., Durazo-Arvizu, R., Biller, J., Flaster, M., Morales-Vidal, S., Ruland, S., Ray, J. Tags: Prehospital/Emergency Room Stroke Care and Intracerebral Hemorrhage Source Type: research

Patient care with empathy and acceptance: How not why
"Why?" my mother asked, not with the exuberant curiosity of a child but with frustration and annoyance. "W-w-h-h-y-y?" This time she enunciated each letter as if trying to will it into a different sound to form the word she was actually trying to express. Flustered, she just started repeating herself, "Why? Why? Why?" I could tell our collective patience and resolve to communicate was wavering.
Source: Neurology - November 23, 2015 Category: Neurology Authors: Jaremko, K. M. Tags: Other cerebrovascular disease/ Stroke, Aphasia, All Education, Professional conduct and ethics REFLECTIONS: NEUROLOGY AND THE HUMANITIES Source Type: research

Clinical Reasoning: A 66-year-old man with recurrent multi-territory infarcts
A 66-year-old man was referred to our center for evaluation of recurrent infarcts in multiple vascular territories over the preceding 6 months (figure 1). The patient first presented with a 3-month, stuttering course of transient neurologic deficits, including right arm and leg hemiparesis, expressive aphasia, and right homonymous hemianopia. He was initially evaluated at a community Stroke Prevention Clinic. His medical history was significant for several classic vascular risk factors: coronary artery disease requiring a coronary artery bypass graft, dyslipidemia for which he was taking atorvastatin 20 mg daily, and obstr...
Source: Neurology - June 8, 2015 Category: Neurology Authors: Kouzmitcheva, E., Steriade, C., Prica, A., Hazrati, L.-N., Mandell, D. M. Tags: All Cerebrovascular disease/Stroke, All Education RESIDENT AND FELLOW SECTION Source Type: research

Teaching Video NeuroImages: Movement of a paralyzed arm with yawning
A 63-year-old man presented with aphasia and right arm paralysis (Medical Research Council [MRC] grade 0), sparing the leg (video 1 on the Neurology® Web site at Neurology.org). With yawning, his right arm consistently rose to his chest (video 2). Paralysis resumed after yawning. MRI confirmed an acute ischemic stroke in the left middle cerebral artery distribution (figure). This movement ceased after 2 weeks following partial recovery of arm strength (MRC grade 4). This phenomenon, first described in the 1844, was recently coined parakinesia brachialis oscitans. It is speculated to be a release event in which damaged ...
Source: Neurology - April 20, 2015 Category: Neurology Authors: Kang, P., Dhand, A. Tags: Clinical neurology examination, All Movement Disorders, All Education, Infarction RESIDENT AND FELLOW SECTION Source Type: research

Short-Term Functional Outcome and its Predictors in a Hospital-Based Cohort of Nigerians with Acute Stroke (P5.171)
CONCLUSIONS: About 1 in 3 stroke patients in this cohort had poor functional outcome. In order to improve functional outcome and reduce the burden of stroke in Nigeria, public health education on early recognition and hospital presentation is needed. In acute stroke management, complications should be prevented while speech and language therapy should be instituted to improve functional outcome.Disclosure: Dr. Wahab has nothing to disclose. Dr. Sanya has nothing to disclose. Dr. Ademiluyi has nothing to disclose. Dr. Bello has nothing to disclose. Dr. Alaofin has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Wahab, K., Sanya, E., Ademiluyi, B., Bello, A., Alaofin, W. Tags: Cerebrovascular Disease and Interventional Neurology: Recovery and Rehabilitation Source Type: research

Medication Self-Administration after Stroke (P5.181)
Conclusion: Stroke patients performed poorly on the HMS, and though performance improved after medication education, this may be related to spontaneous stroke recovery. MSA problems, assessed by HMS performance, may strongly predict post-acute care needs. Funded by: NJ Brain Injury Commission and Kessler FoundationDisclosure: Dr. Oyawusi has nothing to disclose. Dr. Levy has nothing to disclose. Dr. Gentile has nothing to disclose. Dr. March has nothing to disclose. Dr. Hreha has received personal compensation for activities with Kessler Institute for Rehabilitation. Dr. Pagaoa-Cruz has nothing to disclose. Dr. Masmela has...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Oyawusi, M., Levy, B., Gentile, A., March, G., Hreha, K., Pagaoa-Cruz, G., Masmela, J., Galletta, E., Holman, S., McKenna, C., Zhang, J., Barrett, A. Tags: Neuro-rehabilitation: Stroke Source Type: research

Predictors of Recovery of Chronic Aphasia (P6.228)
Conclusions: Chronic aphasia recovery is positively influenced by higher education, smaller lesions, younger age, and current antidepressant use (independently of one another).*Study supported by: NIH R01 DC05375Disclosure: Dr. Suneja has nothing to disclose. Dr. Gonzalez-Fernandez has nothing to disclose. Dr. Hillis has received research support from Allon Pharmaceutical.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Suneja, A., Gonzalez-Fernandez, M., Hillis, A. Tags: Aging, Dementia, and Cognitive and Behavioral Neurology: Language Source Type: research

Stroke Survivors with Aphasia May Overestimate Communication Skills: Survivor versus Caregiver Report (S45.001)
ConclusionsStroke survivors with aphasia can give information on their own communication skills with the Communicative Effectiveness Index_this information may be very useful for therapy planning. However, cognitive anosognosia may prevent this information from being fully objective. Specific counseling to survivors and caregivers may help prevent differences in communication perception from becoming barriers to care. Future research should also explore whether current aphasia treatment.is effective at evaluating and addressing self-awareness of communication ability.Supported by: Kessler Foundation, O’Brien Technolo...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Behravan, V., Maniscalco, J., Williamson, D., Barrett, A. Tags: Cerebrovascular Disease and Interventional Neurology: Rehabilitation, Recovery, and Complications Source Type: research

Stroke Mortality And Its Predictors In Nigeria: Results Of A Hospital-Based Study (P2.120)
Conclusion: The 30-day case fatality rate among our stroke patients is high while the independent predictors of this outcome are severity of stroke on admission and presence of complications. Continuing health education of the public on stroke recognition and the need for early hospital presentation is necessary while optimal management of cases in a stroke care unit is advocated in order to improve outcome.Disclosure: Dr. Wahab has nothing to disclose. Dr. Sanya has nothing to disclose. Dr. Ademiluyi has nothing to disclose. Dr. Abiodun has nothing to disclose. Dr. Alaofin has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Wahab, K., Sanya, E., Ademiluyi, B., Abiodun, B., Alaofin, W. Tags: Cerebrovascular Disease and Interventional Neurology: Behavioral, Cognitive, and Miscellaneous Source Type: research

Measuring Health-Related Quality Of Life (HRQOL) During Inpatient Stroke Rehabilitation (S21.002)
CONCLUSIONS: EQ-5 ratings converged between stroke survivors and clinicians, suggesting it is valid and reliable to measure moderate stroke survivor HRQOL in inpatient rehabilitation. EQ-5 and FIM improvement were poorly associated; HRQOL may independently complement functional outcome assessment in inpatient rehabilitation. Future studies could explore different areas of function to clarify the factor structure of improvement on these measures relative to HRQL.Study Supported by: NIH, Kessler FoundationDisclosure: Dr. Frisina has received personal compensation for activities with Kessler Institute for Rehabilitation as an...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Frisina, P., Kutlik, A., Hreha, K., Barrett, A. Tags: Neuro-rehabilitation and Neural Repair Source Type: research

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