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Comorbidity profile in dementia with Lewy bodies versus Alzheimer’s disease: a linkage study between the Swedish Dementia Registry and the Swedish National Patient Registry
Conclusions: Our study indicated a worse comorbidity profile in DLB patients with higher occurrence of depression, stroke and migraine compared with the AD group. Deeper knowledge about the underlying mechanisms of these associations is needed to explore possible reasons for the different pattern of comorbidity profile in DLB compared to AD and their prognostic significance.
Source: Epidemiologic Perspectives and Innovations - October 6, 2014 Category: Epidemiology Authors: Seyed-Mohammad FereshtehnejadSoheil DamangirPavla CermakovaDag AarslandMaria EriksdotterDorota Religa Source Type: research

Little evidence that cholinesterase inhibitors prevent progression of mild cognitive impairment to dementia, but they are associated with adverse effects
Question Question: How effective and safe are cholinesterase inhibitors for mild cognitive impairment? Outcomes: Progression to dementia or Alzheimer's disease (National Institute of Neurological and Communicative Disorders and Stroke and the Alzheimer's disease and Related Disorders Association (NINDS-ARDRA), International Classification of Diseases (ICD)-10 or Diagnostic and Statistical Manual (DSM-IV criteria), dementia with Lewy bodies or vascular dementia (consensus criteria) at 12, 24 and 36 months and adverse events. Methods Design: Systematic review with meta-analysis. Data sources: Cochrane Dementia and Cogni...
Source: Evidence-Based Mental Health - April 12, 2013 Category: Psychiatry & Psychology Authors: Rojas-Fernandez, C. H. Tags: Clinical trials (epidemiology), Neurology, Dementia, Alzheimer's type, Dementia, vascular, Psychiatry of old age, Primary insomnia, Epidemiology Therapeutics Source Type: research