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Low annual frequency of HbA1c testing in people with Type 2 diabetes in primary care practices in Germany
ConclusionsOnly three out of four individuals with Type 2 diabetes underwent at least two HbA1c tests in Germany in 2016, which means that 25% of individuals underwent fewer tests than required by German guidelinesThis article is protected by copyright. All rights reserved.
Source: Diabetic Medicine - November 25, 2017 Category: Endocrinology Authors: K. Kostev, L. Jacob, W. Rathmann Tags: Research Article Source Type: research

Modelling incremental benefits on complications rates when targeting lower HbA1c levels in people with Type 2 diabetes and cardiovascular disease
ConclusionsThese simulated complication rates might help inform the degree to which complications might be reduced by targeting particular HbA1c reductions in Type 2 diabetes.This article is protected by copyright. All rights reserved.
Source: Diabetic Medicine - October 23, 2017 Category: Endocrinology Authors: S. A. Mostafa, R. L. Coleman, O. F. Agbaje, A. M. Gray, R. R. Holman, M. A. Bethel Tags: Research Article Source Type: research

Incident ischaemic stroke and Type 2 diabetes: trends in incidence and case fatality in Scotland 2004 –2013
ConclusionsIschaemic stroke incidence declined no faster in people with a diagnosis of Type 2 diabetes than in people without diabetes. Increasing prevalence of Type 2 diabetes among stroke patients may mean that declines in case fatality over time will be less marked in the future.This article is protected by copyright. All rights reserved.
Source: Diabetic Medicine - October 17, 2017 Category: Endocrinology Authors: S. H. Read, D. A. McAllister, H. M. Colhoun, B. Farran, C. Fischbacher, J. J. Kerssens, G. P. Leese, R. S. Lindsay, R. J. McCrimmon, S. McGurnaghan, S. Philip, N. Sattar, S. H. Wild, Tags: Research Article Source Type: research

Association between serum 25(OH)D3 and cardiovascular morbidity and mortality in people with Type 2 diabetes: a community ‐based cohort study
ConclusionsLow 25(OH)D3 is associated with an increased risk of cardiovascular morbidity and mortality in people with Type 2 diabetes independent of parathyroid hormone. Vitamin D could be considered as a prognostic factor. Future studies are needed to explore whether vitamin D deficiency is a modifiable risk factor in Type 2 diabetes.
Source: Diabetic Medicine - January 18, 2017 Category: Endocrinology Authors: M. Samefors, R. Scragg, T. L änne, F. H. Nyström, C. J. Östgren Tags: Research: Metabolism Source Type: research

Long ‐term excess risk of stroke in people with Type 2 diabetes in Sweden according to blood pressure level: a population‐based case–control study
ConclusionsPeople with Type 2 diabetes and blood pressure < 130/80 mmHg had a risk of stroke similar to that of the general population.This article is protected by copyright. All rights reserved.
Source: Diabetic Medicine - November 24, 2016 Category: Endocrinology Authors: C. H. Stahl, M. Lind, A. ‐M. Svensson, M. Kosiborod, S. Gudbjörnsdottir, A. Pivodic, M. Clements, A. Rosengren Tags: Original Article Source Type: research

Identifying the independent effect of HbA1c variability on adverse health outcomes in patients with Type 2 diabetes
ConclusionsIn veterans with Type 2 diabetes, greater HbA1c variability was associated with an increased risk of adverse long‐term outcomes, independently of HbA1c levels and direction of change. Limiting HbA1c fluctuations over time may reduce complications.This article is protected by copyright. All rights reserved.
Source: Diabetic Medicine - June 8, 2016 Category: Endocrinology Authors: J. C. Prentice, S. D. Pizer, P. R. Conlin Tags: Research Article Source Type: research

Mortality and cardiovascular disease outcomes among 740 patients with new‐onset Type 2 diabetes detected by screening or clinically diagnosed in general practice
ConclusionsNo reduction in total mortality or CVD outcomes was found in patients with Type 2 diabetes that was detected by screening compared with those diagnosed clinically.This article is protected by copyright. All rights reserved.
Source: Diabetic Medicine - October 30, 2015 Category: Endocrinology Authors: S. P. O. Jansson, D. K. G. Andersson, K. Svärdsudd Tags: Research Article Source Type: research

Low alanine aminotransferase levels and higher number of cardiovascular events in people with Type 2 diabetes: analysis of the Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) study
ConclusionsThe data may indicate that in people with Type 2 diabetes, which is associated with higher alanine aminotransferase levels because of prevalent non‐alcoholic fatty liver disease, a low alanine aminotransferase level is a marker of hepatic or systemic frailty rather than health.This article is protected by copyright. All rights reserved.
Source: Diabetic Medicine - October 3, 2015 Category: Endocrinology Authors: K. H. Williams, D. R. Sullivan, A. S. Veillard, R. O'Brien, J. George, A. J. Jenkins, S. Young, C. Ehnholm, A. Duffield, S. M. Twigg, A. C. Keech Tags: Research Article Source Type: research

Cardiovascular risks associated with second‐line oral antidiabetic agents added to metformin in patients with Type 2 diabetes: a nationwide cohort study
ConclusionThere were no differences in overall cardiovascular risks among several add‐on second‐line oral antidiabetic agents; however, glinide plus metformin and α‐glucosidase inhibitors plus metformin combination therapies might be associated with lower risks of acute myocardial infarction.This article is protected by copyright. All rights reserved.
Source: Diabetic Medicine - May 1, 2015 Category: Endocrinology Authors: Y.‐C. Chang, L.‐M. Chuang, J.‐W. Lin, S.‐T. Chen, M.‐S. Lai, C.‐H. Chang Tags: Research Article Source Type: research

Impact of diabetes‐related complications on healthcare costs: new results from the UK Prospective Diabetes Study
ConclusionsDiabetic complications are associated with substantial immediate and long‐term healthcare costs. Our comprehensive new estimates of these costs, derived from detailed recent UK Prospective Diabetes Study post‐trial data, should aid researchers and health policy analyses.This article is protected by copyright. All rights reserved.
Source: Diabetic Medicine - November 29, 2014 Category: Endocrinology Authors: M. L. Alva, A. Gray, B. Mihaylova, J. Leal, R. R. Holman Tags: Research Article Source Type: research

The impact of diabetes‐related complications on healthcare costs: new results from the UKPDS (UKPDS 84)
ConclusionsDiabetic complications are associated with substantial immediate and long‐term healthcare costs. Our comprehensive new estimates of these costs, derived from detailed recent UK Prospective Diabetes Study post‐trial data, should aid researchers and health policy analyses.This article is protected by copyright. All rights reserved.
Source: Diabetic Medicine - November 29, 2014 Category: Endocrinology Authors: M. L. Alva, A. Gray, B. Mihaylova, J. Leal, R. R. Holman Tags: Research Article Source Type: research

Gender differences and patterns of cardiovascular risk factors in Type 1 and Type 2 diabetes: a population‐based analysis from a Scottish region
ConclusionsThe study shows gender differences between Type 1 and 2 diabetes that are of clinical significance and require further investigation. Follow‐up of the patients included in the present study should give us much greater understanding of the importance of gender in the development of metabolic abnormalities and diabetes complications.This article is protected by copyright. All rights reserved.
Source: Diabetic Medicine - August 23, 2014 Category: Endocrinology Authors: A. Collier, S. Ghosh, M. Hair, N. Waugh Tags: Research Article Source Type: research

Effects of fasting blood glucose levels and blood pressure and treatment of diabetes and hypertension on the incidence of cardiovascular disease: a study of 740 patients with incident Type 2 diabetes with up to 30 years’ follow‐up
ConclusionsThe cumulative incidence of cardiovascular disease and myocardial infarction increased with number of previous events and presence of hyperglycaemia and hypertension and decreased with pharmacological treatment of diabetes. A higher number of previous stroke events increased the cumulative incidence of stroke but no protective effect of pharmacological treatment was observed.This article is protected by copyright. All rights reserved.
Source: Diabetic Medicine - June 1, 2014 Category: Endocrinology Authors: S.P.O. Jansson, D.K.G. Andersson, K. Svärdsudd Tags: Research Article Source Type: research

Predicting mortality in people with Type 2 diabetes mellitus after major complications: a study using Swedish National Diabetes Register data
ConclusionsRisk of death and life expectancy differs substantially among the major complications of diabetes, and factors significantly increasing risk included smoking, low estimated GFR and albuminuria.This article is protected by copyright. All rights reserved.
Source: Diabetic Medicine - April 17, 2014 Category: Endocrinology Authors: P. J. Kelly, P. M. Clarke, A.J. Hayes, U.‐G. Gerdtham, J. Cederholm, P. Nilsson, B . Eliasson, S. Gudbjornsdottir Tags: Research Article Source Type: research