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Condition: Bleeding
Procedure: Coronary Angioplasty
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Total 1099 results found since Jan 2013.
Aspirin in the Modern Era of Cardiovascular Disease Prevention
Methodist Debakey Cardiovasc J. 2021 Sep 24;17(4):36-47. doi: 10.14797/mdcvj.293. eCollection 2021.ABSTRACTAspirin's antithrombotic effects have a long-established place in the prevention of cardiovascular disease (CVD), and its traditional use as a core therapy for secondary prevention of CVD is well recognized. However, with the advent of newer antiplatelet agents and an increasing understanding of aspirin's bleeding risks, its role across the full spectrum of modern CVD prevention has become less certain. As a consequence, recent trials have begun investigating aspirin-free strategies in secondary prevention. For exampl...
Source: Methodist DeBakey Cardiovascular Journal - November 26, 2021 Category: Cardiology Authors: Ella Murphy James M G Curneen John W McEvoy Source Type: research
Outcomes of Radial Versus Femoral Access in Patients With Severe Aortic Stenosis Undergoing Percutaneous Coronary Intervention Prior to Transcatheter Aortic Valve Replacement
CONCLUSION: Radial access for pre-TAVR PCI is feasible and safe and is associated with a lower rate of access-site hematoma. This study supports the increased use of transradial access for pre-TAVR PCI.PMID:35501112
Source: The Journal of Invasive Cardiology - May 2, 2022 Category: Cardiology Authors: Salman Farhat Abdallah El Sabbagh Mohammed Al-Hijji Keniel Pierre Nahyr S Lugo-Fagundo Yader Sandoval Michael S Gharacholou Peter M Pollak Mandeep Singh Mackram F Eleid Mohammed Al-Khouli David R Holmes Mayra Guerrero Rajiv Gulati Malcolm Bell Charanjit S Source Type: research
De-escalation of Dual Antiplatelet Therapy After Percutaneous Coronary Intervention in Patients With Acute Coronary Syndrome: An Updated Meta-analysis and Trial Sequential Analysis of 21 Studies and 38,741 Patients
Abstract:
Dual antiplatelet therapy (DAPT) is recommended among patients with established acute coronary syndrome. In this meta-analysis, we sought to compare the clinical outcomes between de-escalation versus unchanged DAPT based on both randomized controlled trials (RCTs) and observational studies. The primary outcomes were major adverse cardiovascular events for observational studies and net clinical events for RCTs. Four RCTs and 17 observational studies with a total of 38,741 patients were included. Net clinical events were more common with unchanged DAPT than with de-escalation in RCTs [odd ratio (OR): 1.71; 95% ...
Source: Journal of Cardiovascular Pharmacology - June 1, 2022 Category: Cardiology Tags: Original Article Source Type: research
Efficacy and Safety of De-escalation of Antiplatelet Therapy After Percutaneous Coronary Intervention in Patients With Acute Coronary Syndrome: A Meta-Analysis of Randomized Clinical Trials
Abstract:
Considering that there is no definite conclusion on the efficacy and safety of switching from potent P2Y12 inhibitors to clopidogrel, we conducted a systematic review and meta-analysis of patients with acute coronary syndromes undergoing percutaneous coronary intervention and compared the efficacy and safety of de-escalation or not of antiplatelet therapy. The relevant randomized controlled trials were included by searching several databases. Net adverse clinical events were identified as the composite end point, which was defined as a composite of cardiovascular death, myocardial infarction, revascularizatio...
Source: Journal of Cardiovascular Pharmacology - August 1, 2022 Category: Cardiology Tags: Original Article Source Type: research
