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A Common Data Language for Clinical Research Studies: The National Institute of Neurological Disorders and Stroke, National Institutes of Health and Department of Defense Traumatic Brain Injury Sports Concussion Common Data Elements Version 1.0 Recommendations (P6.161)
Conclusions:NINDS encourages the use of CDEs by the clinical research community in order to standardize data collection across studies. The NINDS CDEs are a continually evolving resource, requiring updates as research advancements indicate. These newly developed sport concussion CDEs serve to be a valuable starting point for researchers and facilitate streamlining and sharing data.Study Supported by: This project was funded by HHSN271201200034C.Disclosure: Dr. Joseph has nothing to disclose. Dr. Odenkirchen has nothing to disclose. Dr. Alai has nothing to disclose. Dr. Esterlitz has nothing to disclose. Dr. Tanveer has not...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Joseph, K., Odenkirchen, J., Alai, S., Esterlitz, J., Tanveer, S., Bellgowan, P. Tags: Neuro Trauma and Sports Neurology II Source Type: research

The Clinical and Neuropathological Correlates of Second-Impact Syndrome: Case Report of a 17-year-old Female Rugby Player (P6.164)
Conclusions:This is the first case study to report the clinical and neuropathological features of SIS. Larger autopsy samples are needed to systematically identify clinicopathological correlates of SIS to facilitate research on risk factors and preventative strategies (e.g., return-to-play guidelines) to prevent unnecessary fatalities in young athletes.Study Supported by: This work was supported by the National Institute of Neurological Disorders and Stroke (1U01NS086659-01, U01NS093334, R01NS078337, R56NS078337), Department of Defense (W81XWH-13-2-0064), Department of Veterans Affairs, the Veterans Affairs Biorepository (...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Mian, M., Alosco, M., Mez, J., Kiernan, P., Daneshvar, D., Nowinski, C., Kowall, N., Stern, R., Katz, D., Cantu, R., McKee, A. Tags: Neuro Trauma and Sports Neurology II Source Type: research

Characterization of pain and fatigue following deployment-related mild traumatic brain injury (P5.149)
Conclusions:This exploratory analysis suggests that severity of headache pain and degree of fatigue are interrelated following mTBI, and the most prominent dimensions of fatigue are general, mental and reduced activity, rather than reduced motivation.Study Supported by:National Institute of Neurological Disorders and Stroke Clinical Neuroscience ProgramDisclosure: Dr. Lewis has nothing to disclose. Dr. Knutson has nothing to disclose. Dr. Wassermann has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Lewis, J., Knutson, K., Wassermann, E. Tags: Clinical Neuro-rehabilitation Source Type: research

Spectrum of Neurological Disorders Among 19th Century and Early to Mid-20th Century United States Presidents (P6.334)
Conclusion: Neurological conditions are common among presidents of the United States and sometimes have led to catastrophic events. These conditions also had a significant effect on their careers as well as the course of history. Recognizing and understanding the effects of these conditions on past presidency will lead to better management of the tenure of upcoming presidents.Disclosure: Dr. Govindarajan has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Govindarajan, R. Tags: History of Neurology Source Type: research

Concussion and the neurologist: A work in progress
In the last 3 decades, the neurology landscape has changed. Once primarily an academic profession with limited treatment options, neurology now is a clinical field with treatments available in the acute care setting. Treatment of an acute ischemic stroke may begin with tissue plasminogen activator given in the emergency room within 4.5 hours of symptoms.1 This clinical shift now includes the evaluation and management of concussion patients. With the current estimate from the Centers for Disease Control and Prevention being 1.6–3.8 million sports- and recreation-related concussions per year (up from the prior estimate...
Source: Neurology - July 21, 2014 Category: Neurology Authors: Deibert, E. Tags: EDITORIALS Source Type: research