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To distinguish IgG4-related disease from seronegative granulomatosis with polyangiitis
Rheumatology key messageIgG4-related disease might be an alternative diagnosis in limited granulomatosis with polyangiitis. Sir, IgG4-related disease (IgG4-RD) is a fibro-inflammatory disease that can affect almost every organ [1]. Indeed, previous unexplained conditions have now been reclassified as primarily IgG4-RD and may imitate many inflammatory, infectious and malignant disorders often leading to a delay in diagnosis or incorrect diagnosis. Nasal manifestation of IgG4-RD, mostly of the paranasal sinuses, has previously been described in case reports, but it can also manifest as a primary or secondary nasal disease s...
Source: Rheumatology - September 5, 2017 Category: Rheumatology Source Type: research