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Cancer: Epithelial Cancer
Infectious Disease: Helicobacter Pylori
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Total 141 results found since Jan 2013.
IL-8 Links NF- κB and Wnt/β-Catenin Pathways in Persistent Inflammatory Response Induced by Chronic Helicobacter pylori Infection
Mol Biol (Mosk). 2023 Jul-Aug;57(4):713-716.ABSTRACTHelicobacter pylori (H. pylori) infection can cause persistent inflammatory response in human gastric mucosal epithelial cells, which may result in the occurrence of cancer. However, the underlying mechanism of carcinogenesis has not been elucidated yet. Herein, we established the models of chronic H. pylori infection in GES-1 cells and C57BL/6J mice. Interleukin 8 (IL-8) level was detected by ELISA. The expression of NF-κB p65, IL-8, Wnt2 and β-catenin mRNA and proteins was evaluated by real-time PCR, Western blotting, immunofluorescence staining, and immunohistochemis...
Source: Molekuliarnaia Biologiia - August 2, 2023 Category: Molecular Biology Authors: L Lin B Xie J Shi C M Zhou J Yi J Chen J X He H L Wei Source Type: research
