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Targeted drug delivery in pulmonary therapy based on adhesion and transmission of nanocarriers designed with a metal-organic framework
This study aimed to design a magnetic field-assisted targeted drug delivery system to the lungs using three types of metal-organic frameworks (MOFs) and nanoliposomes. The optimization of the system was based on three main parameters: the surface density of the nanocarriers' (NCs) adherence to each of the lung branches, the amount of drug transferred to each branch, and the toxicity based on the rate of nanocarrier delivery to the branches. The study investigated the effect of increasing the diameter of the drug carriers and the amount of drug loaded onto the NCs in improving drug delivery to targeted areas of the lung. Re...
Source: Biomechanics and Modeling in Mechanobiology - August 25, 2023 Category: Biomedical Science Authors: Hamed Ranjbar Amirhamzeh Farajollahi Mohsen Rostami Source Type: research

COVID-19: A Review on the Role of Trace Elements Present in Saudi Arabian Traditional Dietary Supplements
Pak J Biol Sci. 2022 Jan;25(1):1-8. doi: 10.3923/pjbs.2022.1.8.ABSTRACTThe novel coronavirus infection is also called COVID-19 (coronavirus disease 2019). The infection has affected millions of people worldwide and caused morbidity as well mortality in patients with pre-existing chronic conditions such as metabolic, respiratory and cardiovascular disorders. The severity of the disease is mostly seen in people with low immunity and chronic sufferers of respiratory, cardiovascular and metabolic disorders. To date, there is no specific treatment available for COVID-19. Precaution and prevention are the most recommended option...
Source: Pakistan Journal of Biological Sciences: PJBS - January 10, 2022 Category: Biomedical Science Authors: Hani A Alfheeaid Syed Imam Rabbani Source Type: research

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