ESC hot line ACCOAST was halted; bleeds, no benefit with earlier prasugrel
A slide set from a French Cardiology Society presentation in Paris this past January is one of the only online mentions that anything had gone awry with this study, which was testing use of prasugrel at the time of PCI vs pretreatment at the time of diagnosis in patients with non-STEMI. (Source: theHeart.org)
Source: theHeart.org - August 28, 2013 Category: Cardiology Source Type: news

Genetic variant linked with increased CHD risk in diabetics identified
A study undertaken by Harvard researchers identifies a genetic variant that might help explain why diabetic patients are at an increased risk of coronary heart disease. (Source: theHeart.org)
Source: theHeart.org - August 27, 2013 Category: Cardiology Source Type: news

Cardiovascular autonomic dysfunction predicts outcomes in diabetes
Among patients with type 2 diabetes and CAD, heart-rate recovery after exercise as well as other measures of autonomic function predict short-term cardiovascular outcomes, but C-reactive protein is a better predictor of adverse events, a study suggests. A second study reports that autonomic dysfunction is a strong predictor of risk of severe hypoglycemia in patients with type 2 diabetes. (Source: theHeart.org)
Source: theHeart.org - August 27, 2013 Category: Cardiology Source Type: news

German CoreValve use on hold, as court injunction goes into effect
Edwards, which successfully won a recent patent battle against Medtronic, says it is "reaching out" to make sure doctors unaccustomed to using the Sapien get the training they need. (Source: theHeart.org)
Source: theHeart.org - August 27, 2013 Category: Cardiology Source Type: news

Raising awareness: EAS says FH underdiagnosed and undertreated
The EAS says that while the theoretical prevalence of heterozygous FH is 1/500, some estimates suggest that the true prevalence of heterozygous FH is 1/200. Globally, less than 1% of individuals with FH are diagnosed. (Source: theHeart.org)
Source: theHeart.org - August 26, 2013 Category: Cardiology Source Type: news

RECORD readjudication rosy for rosiglitazone
A Duke University readjudication of the original trial suggests little difference from the original trial, which did not find an increased CV risk for rosiglitazone. (Source: theHeart.org)
Source: theHeart.org - August 26, 2013 Category: Cardiology Source Type: news

USPSTF guidelines: Counseling prevents youth smoking
New evidence has shown that simple, economical, and effective primary-care interventions can help prevent tobacco use among children and teenagers, according to new USPSTF guidelines. (Source: theHeart.org)
Source: theHeart.org - August 26, 2013 Category: Cardiology Source Type: news

What's going to be hot at ESC 2013 Congress
Along with some of the usual suspects, this year's ESC program includes a few "out-in-left-field" papers in the lineup of hot-line studies, plus a number of other innovations that the program committee hopes will help remind physicians that the heart is just one organ within the "spectrum of disease." (Source: theHeart.org)
Source: theHeart.org - August 23, 2013 Category: Cardiology Source Type: news

A shot in arm, a boost for the heart: Flu vaccination reduces AMI risk
Yet another study, this time a case-control study from Australia, suggests there is a cardiovascular benefit to getting a flu shot. (Source: theHeart.org)
Source: theHeart.org - August 23, 2013 Category: Cardiology Source Type: news

High urinary albumin predicts risk of new MI in blacks
A high albumin-to-creatine ratio may predict an imminent MI in black patients, but not in white patients, new research suggests. More research is needed to untangle what lies behind these racial differences and whether identifying at-risk patients could improve outcomes. (Source: theHeart.org)
Source: theHeart.org - August 23, 2013 Category: Cardiology Source Type: news

Severe hypoglycemia may lead to fatal arrhythmia
Patients with type 1 or type 2 diabetes who develop severe hypoglycemia and end up visiting a hospital emergency department often arrive with clinical factors that put them at risk for lethal arrhythmia, new research suggests. (Source: theHeart.org)
Source: theHeart.org - August 23, 2013 Category: Cardiology Source Type: news

Public Citizen to FDA: No more clopidogrel one year post-DES
The consumer watchdog group wants the agency to revise the warning labeling, distribute an updated patient guide, and ask companies to send "Dear Doctor" letters warning of preventable bleeding adverse effects that occur after one year of clopidogrel use. (Source: theHeart.org)
Source: theHeart.org - August 21, 2013 Category: Cardiology Source Type: news

Remote ischemic preconditioning prior to CABG improves long-term survival
It's simple, it's cheap, and now results from a single center suggest that ischemic preconditioning prior to CABG surgery using a blood-pressure cuff has benefits that extend beyond myocardial protection. (Source: theHeart.org)
Source: theHeart.org - August 21, 2013 Category: Cardiology Source Type: news

Right drugs, inadequate dose: Do AMI performance measures need dosing data?
A new analysis looking at discharge medications in almost 7000 AMI patients found that while most patients are leaving hospitals on the recommended drugs, the vast majority are not getting doses that will actually help them avoid future events. (Source: theHeart.org)
Source: theHeart.org - August 21, 2013 Category: Cardiology Source Type: news

Mediterranean diet may reverse genetic risk for stroke
Eating nuts, fresh vegetables, fruits, and olive oil affects lipid and glucose levels and appears to reduce stroke in patients at high genetic risk for diabetes and CVD. (Source: theHeart.org)
Source: theHeart.org - August 21, 2013 Category: Cardiology Source Type: news