Human embryo discovery wins People ’s Choice of Science Breakthrough of the Year
A revolutionary system that allows researchers to study human embryo development in the lab was chosen by Science magazine readers as the scientific advancement of 2016 that has done the most to benefit humanity, answer long-standing questions, or pave the way for fruitful research. More » (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - December 22, 2016 Category: Biomedical Science Authors: Katie Fenz Tags: Awards and Honors Ali Brivanlou embryo development Eric Siggia Laboratory of Stem Cell Biology and Molecular Embryology Science Breakthrough of the Year Source Type: news

New molecular map reveals how cells spew out potassium
Researchers have determined for the first time the complete structure of an ion channel known as BK, or “big potassium.” This molecular map offers new insights on how BK works and may aid in the development of treatments for diseases in which it malfunctions. More » (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - December 22, 2016 Category: Biomedical Science Authors: Wynne Perry Tags: Science News BK Laboratory of Neurobiology and Biophysics potassium Richard Hite Roderick MacKinnon Slo1 structural and chemical biology Xiao Tao Source Type: news

In the News – Reuters – Brady
NYC dirt has scientists digging for antibiotic success   “Researchers at The Rockefeller University in New York City have found that bacteria extracted from local parks contain genes that might encode drug-like molecules like antibiotics, immunosuppressants, and cancer-curing agents. ‘Almost … More » (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - December 19, 2016 Category: Biomedical Science Authors: Katie Fenz Tags: In the News antibiotics drugs from dirt Laboratory of Genetically Encoded Small Molecules New York City Sean Brady Zachary Charlop-Powers Source Type: news

New structure shows how cells assemble protein-making machinery
Researchers have created the most detailed images to date of a particle destined to become part of a ribosome. Their findings gave them a new view of how these essential nano-machines are put together. More » (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - December 15, 2016 Category: Biomedical Science Authors: Wynne Perry Tags: Science News chemical and structural biology cryo-electron microscopy cryo-EM Laboratory of Protein and Nucleic Acid Chemistry Malik Chaker-Margot ribosome sebastian klinge small ribosomal subunit Source Type: news

Fifty years after landmark methadone discovery, stigmas and misunderstandings persist
In 1966, Rockefeller scientists published a landmark paper that would lead to the first medical treatment for heroin addiction. The drug has helped millions of heroin users around the world, yet its use in the United States remains controversial. More » (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - December 9, 2016 Category: Biomedical Science Authors: Katie Fenz Tags: Science News addiction anniversary Laboratory of the Biology of Addictive Diseases Mary Jeanne Kreek methadone Rockefeller History Source Type: news

First structural map of the cystic fibrosis protein sheds light on how mutations cause disease
A map that shows the arrangement of atoms within the cystic fibrosis protein will help researchers better understand how specific mutations cause disease. Ultimately, this knowledge may reveal potential targets for new drugs. More » (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - December 1, 2016 Category: Biomedical Science Authors: Wynne Perry Tags: Science News CFTR cryo-electron microscopy cystic fibrosis Jue Chen structural and chemical biology Zhe Zhan Source Type: news

Elaine Fuchs to receive 2016 Vanderbilt Prize in Biomedical Science
The prize, given by Vanderbilt University School of Medicine, recognizes women with outstanding research accomplishments who have also made significant contributions to mentoring other women in science. Fuchs is being honored for her innovative use of reverse genetics to understand skin diseases and cancer stem cells. More » (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - November 28, 2016 Category: Biomedical Science Authors: Katie Fenz Tags: Awards and Honors cancer stem cells Elaine Fuchs Laboratory of Mammalian Cell Biology and Development skin disease Vanderbilt Prize Source Type: news

In the News – Wall Street Journal – Brady
New York City Dirt Rich in Bacteria Related to Medical Treatments   “Traditionally, researchers seeking new clinical compounds treated cities as a barren asphalt jungle, lacking the natural diversity of micro-organisms found in unspoiled regions. Using New York as a … More » (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - November 28, 2016 Category: Biomedical Science Authors: Katie Fenz Tags: In the News drugs from dirt Laboratory of Genetically Encoded Small Molecules New York City Sean Brady Source Type: news

Survey of New York City soil uncovers medicine-making microbes
Sifting soil from city parks, scientists have found microbial genes capable of making compounds whose potent effects can make them valuable tools in the fight against disease. Their research suggests that many more await discovery, even in a place as mundane as urban dirt. More » (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - November 28, 2016 Category: Biomedical Science Authors: Wynne Perry Tags: Science News antibiotics chemical biology drug discovery drugs from dirt medicines microbiology natural products Sean Brady Sean F. Brady soil microbes Zachary Charlop-Powers Source Type: news

Rockefeller ’s Science Outreach program explores the microbes in food
High school students designed research projects to investigate the role that microscopic organisms play in cheeses and other foods. The program aims to let students experience the scientific method firsthand. More » (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - November 18, 2016 Category: Biomedical Science Authors: Katie Fenz Tags: Campus News cheese Jeanne Garbarino microbiome Science Outreach Program Source Type: news

Jean-Laurent Casanova receives the 2016 Inserm Grand Prix
Given by Inserm, the French National Institute of Health and Medical Research, the Grand Prix honors researchers whose work has contributed to the institute’s scientific excellence. Casanova, is being recognized for his work on the genetic basis of infectious diseases. More » (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - November 18, 2016 Category: Biomedical Science Authors: Geoffrey Shearer Tags: Awards and Honors Inserm Grand Prix Jean-Laurent Casanova St. Giles Laboratory of Human Genetics and Infectious Diseases Source Type: news

New research clarifies why wounds heal more slowly with age
With age, it takes longer for skin cells to close an injury. New research shows that a breakdown in communication between these cells and neighboring immune cells causes this delay—a discovery that has implications for improving healing among older people. More » (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - November 17, 2016 Category: Biomedical Science Authors: Wynne Perry Tags: Science News aging Elaine Fuchs Robin Chemers Neustein Laboratory of Mammalian Cell Biology and Development skints wound healing wound repair Source Type: news

Gaby Maimon, who studies sophisticated brain functions in fruit flies, is promoted to associate professor
As head of the Laboratory of Integrative Brain Function, Maimon uses flies to study the computations with which the brain estimates values like angles and time. His promotion is effective January 1. More » (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - November 16, 2016 Category: Biomedical Science Authors: Wynne Perry Tags: Campus News cognition Drosophila melanogaster Gaby Maimon higher brain function Laboratory of Integrative Brain Function neurosciences and behavior promotion Source Type: news

Researchers discover new antibiotics by sifting through the human microbiome
The bacteria we carry within us could be a untapped source of new drugs. Researchers put this idea to the test by mining the human microbiome for new antibiotics—and identified two compounds that might be effective against some particularly dangerous bacteria. More » (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - November 15, 2016 Category: Biomedical Science Authors: Geoffrey Shearer Tags: Science News antibiotics Laboratory of Genetically Encoded Small Molecules medical sciences microbiology microbiome Sean Brady Source Type: news

In the News – The Atlantic – Vosshall
Scientists Stink at Reverse-Engineering Smells   “Through a crowdsourced competition, Andreas Keller and Leslie Vosshall at Rockefeller University and Pablo Meyer at IBM have developed algorithms that can reverse-engineer the smell of a molecule—to predict what it smells like from … More » (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - November 14, 2016 Category: Biomedical Science Authors: Katie Fenz Tags: In the News Source Type: news