Neurocognition, negative symptom effects in psychotic prodrome clarified
The contribution of neurocognition and negative symptoms to impaired social and role functioning in patients at clinical high risk of psychosis is important enough to warrant targeting both with therapeutic interventions, say researchers. (Source: MedWire News - Psychiatry)
Source: MedWire News - Psychiatry - March 7, 2014 Category: Psychiatry Source Type: news

Parents with bipolar disorder feel control by monitoring kids' moods
The majority of parents with bipolar disorder monitor their children's moods, which helps them feel in control of their child's wellbeing, show US study results. (Source: MedWire News - Psychiatry)
Source: MedWire News - Psychiatry - March 7, 2014 Category: Psychiatry Source Type: news

Inflammation and stress combine in bipolar and schizophrenia subtypes
Researchers have found that some individuals with bipolar disorder or schizophrenia have combined stress response and immune dysfunctions. (Source: MedWire News - Psychiatry)
Source: MedWire News - Psychiatry - March 6, 2014 Category: Psychiatry Source Type: news

Community care helps schizophrenia patients in resource-poor settings
Collaborative care delivered by community health workers can improve outcomes among patients with schizophrenia receiving facility-based case in resource-poor settings, shows a study in The Lancet. (Source: MedWire News - Psychiatry)
Source: MedWire News - Psychiatry - March 6, 2014 Category: Psychiatry Source Type: news

Diagnostic errors common among patients with bipolar disorder
Russian study data bolster the existing body of evidence showing that bipolar disorder is often misdiagnosed as depression. (Source: MedWire News - Psychiatry)
Source: MedWire News - Psychiatry - March 5, 2014 Category: Psychiatry Source Type: news

Drug abuse does not always lead to psychosis readmission
Cannabis or stimulant abuse disorders do not necessarily predict a negative outcome for patients with first-episode psychosis, Australian researchers report. (Source: MedWire News - Psychiatry)
Source: MedWire News - Psychiatry - March 5, 2014 Category: Psychiatry Source Type: news

Cancer contributes to schizophrenia mortality
Study findings confirm the increased risk of death from physical diseases among patients with schizophrenia, and reveal cancer mortality as an issue among middle-aged patients. (Source: MedWire News - Psychiatry)
Source: MedWire News - Psychiatry - March 4, 2014 Category: Psychiatry Source Type: news

More support for interhemispheric disconnectivity in bipolar disorder
A UK study supports a role for interhemispheric disconnectivity in bipolar disorder, showing reduced corpus callosum area and thickness in patients with the condition. (Source: MedWire News - Psychiatry)
Source: MedWire News - Psychiatry - March 4, 2014 Category: Psychiatry Source Type: news

BDNF abnormalities may predict bipolar disorder
Patients with bipolar disorder show abnormalities in the conversion of pro-brain derived neurotrophic factor to the mature form, which may be used to aid diagnosis of the condition. (Source: MedWire News - Psychiatry)
Source: MedWire News - Psychiatry - February 28, 2014 Category: Psychiatry Source Type: news

Elevated homocysteine not gender-specific in schizophrenia
Japanese researchers have demonstrated that both men and women with schizophrenia have significantly higher plasma homocysteine levels than healthy controls. (Source: MedWire News - Psychiatry)
Source: MedWire News - Psychiatry - February 28, 2014 Category: Psychiatry Source Type: news

Advanced paternal age effects extend to several psychiatric disorders
The effect of advanced paternal age at childbearing on the psychiatric morbidity risk of their children extends to several psychiatric disorders and particularly bipolar disorder, findings from a sibling-comparison study show. (Source: MedWire News - Psychiatry)
Source: MedWire News - Psychiatry - February 27, 2014 Category: Psychiatry Source Type: news

Further support for hippocampal volume as psychosis biomarker
Findings from the Bipolar-Schizophrenia Network on Intermediate Phenotypes provide further evidence that reduced hippocampal volume is a consistent feature of schizophrenia. (Source: MedWire News - Psychiatry)
Source: MedWire News - Psychiatry - February 27, 2014 Category: Psychiatry Source Type: news

Residual symptoms linked to poor functioning in euthymic bipolar disorder
Residual symptoms are associated with functional impairment in euthymic individuals with bipolar disorder, a large observational study has shown. (Source: MedWire News - Psychiatry)
Source: MedWire News - Psychiatry - February 26, 2014 Category: Psychiatry Source Type: news

Attitudinal beliefs feed negative schizophrenia symptoms
Dysfunctional attitudes and low self-efficacy are associated with poorer functioning in patients with early schizophrenia, and this relationship is partly mediated by negative symptoms, shows research. (Source: MedWire News - Psychiatry)
Source: MedWire News - Psychiatry - February 26, 2014 Category: Psychiatry Source Type: news

Psychoeducation reduces internalised stigmatisation in bipolar patients
A psychoeducation program designed to reduce internalised stigmatisation in patients with bipolar disease resulted in a significant decrease in total mean scores on the Internalized Stigmatization Scale of Mental Illness compared with a control group, a Turkish study shows. (Source: MedWire News - Psychiatry)
Source: MedWire News - Psychiatry - February 25, 2014 Category: Psychiatry Source Type: news

Substance abuse worsens course of first-episode psychosis
Patients with first-episode psychosis who also present with substance abuse have a higher rate of hospitalisation after 12 months than their peers who do not, an Italian study reports. (Source: MedWire News - Psychiatry)
Source: MedWire News - Psychiatry - February 25, 2014 Category: Psychiatry Source Type: news

Factors predicting disengagement from psychosis early intervention identified
A study of first-episode psychosis patients in Hong Kong has found that those with fewer negative symptoms at presentation and poor medication compliance were more likely than others to disengage from an early intervention program. (Source: MedWire News - Psychiatry)
Source: MedWire News - Psychiatry - February 21, 2014 Category: Psychiatry Source Type: news

Comorbid OCD and bipolar disorder should be treated as mood disorder
Most patients with both bipolar disorder and obsessive–compulsive disorder should be treated as having bipolar disorder, researchers suggest. (Source: MedWire News - Psychiatry)
Source: MedWire News - Psychiatry - February 21, 2014 Category: Psychiatry Source Type: news

Support for progranulin role in bipolar disorder
Researchers have found reduced levels of plasma progranulin in patients with bipolar disorder, strengthening evidence for its possible role as a biomarker for the condition. (Source: MedWire News - Psychiatry)
Source: MedWire News - Psychiatry - February 20, 2014 Category: Psychiatry Source Type: news

Psychotherapies have specific effects on psychosis symptoms
There are small but robust differences in the effects of different psychotherapies on psychosis symptoms, say the authors of a meta-analysis. (Source: MedWire News - Psychiatry)
Source: MedWire News - Psychiatry - February 20, 2014 Category: Psychiatry Source Type: news

Stereotype awareness impacts self-esteem in schizophrenia
Patients with psychosis with higher self-esteem have less awareness of the stereotypes associated with mental health patients and their families, research shows. (Source: MedWire News - Psychiatry)
Source: MedWire News - Psychiatry - February 19, 2014 Category: Psychiatry Source Type: news

Mixed state specifier in DSM-5 overlooks the core features
The replacement of “mixed episodes” with “mixed features” in DSM-5 in order to counter a lack of specificity overlooks two of the core features of mixed states, suggests research published in the Journal of Affective Disorders. (Source: MedWire News - Psychiatry)
Source: MedWire News - Psychiatry - February 19, 2014 Category: Psychiatry Source Type: news

Verbal memory may signal disease course in first-episode psychosis
Verbal memory appears to be a predictor of clinical remission in patients with first-episode psychosis, according to Canadian researchers writing in Schizophrenia Research. (Source: MedWire News - Psychiatry)
Source: MedWire News - Psychiatry - February 17, 2014 Category: Psychiatry Source Type: news

Interhemispheric disconnectivity highlighted in bipolar disorder
Research shows that patients with bipolar I disorder have reduced white matter integrity, including in the corpus callosum, which connects the brain’s hemispheres. (Source: MedWire News - Psychiatry)
Source: MedWire News - Psychiatry - February 17, 2014 Category: Psychiatry Source Type: news

Heritable bipolar phenotypes pinned down
A large study has pinpointed brain and behavioural traits that are genetically influenced and associated with bipolar I disorder. (Source: MedWire News - Psychiatry)
Source: MedWire News - Psychiatry - February 14, 2014 Category: Psychiatry Source Type: news

‘Healthy living’ programme fails to lower BMI in overweight psychosis patients
A “healthy living” intervention focused on exercise and diet has failed to impact body mass index in overweight people with psychosis when evaluated in the setting of a randomised controlled trial. (Source: MedWire News - Psychiatry)
Source: MedWire News - Psychiatry - February 14, 2014 Category: Psychiatry Source Type: news

Consistent mania monitoring during perinatal period warranted
Pregnant and postpartum women with bipolar disorder experience clinically severe symptoms, suggesting the need for continued monitoring of mania during this time, say researchers. (Source: MedWire News - Psychiatry)
Source: MedWire News - Psychiatry - February 13, 2014 Category: Psychiatry Source Type: news

Common mutations produce typical schizophrenia brain changes
Mutations in dopamine-related genes have a dose-response effect on prefrontal activation during emotional response inhibition in healthy adults, a study shows. (Source: MedWire News - Psychiatry)
Source: MedWire News - Psychiatry - February 13, 2014 Category: Psychiatry Source Type: news

Rhythmicity of activity linked to bipolar mania
Circadian rhythm disturbances are associated with bipolar disorder, and particularly with mania, indicate study findings. (Source: MedWire News - Psychiatry)
Source: MedWire News - Psychiatry - February 12, 2014 Category: Psychiatry Source Type: news

Urinary tract infections linked to acute psychosis relapse
Patients with an acute episode of psychosis have a high incidence of urinary tract infections, report researchers. (Source: MedWire News - Psychiatry)
Source: MedWire News - Psychiatry - February 12, 2014 Category: Psychiatry Source Type: news

Self-disorders highly specific to schizophrenia spectrum
Self-disorders – also known as anomalous self-experiences – are highly specific to individuals with schizophrenia-spectrum disorders, Danish research indicates. (Source: MedWire News - Psychiatry)
Source: MedWire News - Psychiatry - February 11, 2014 Category: Psychiatry Source Type: news

U-shaped association between paternal age and bipolar risk
Having a father who is relatively young or old may increase a person’s risk of developing bipolar disorder, a study suggests. (Source: MedWire News - Psychiatry)
Source: MedWire News - Psychiatry - February 11, 2014 Category: Psychiatry Source Type: news

Disorganisation, verbal memory help shape QoL in schizophrenia
Disorganisation and cognition each influence quality of life in people with schizophrenia and are promising targets of interventions to improve functional outcomes, say researchers. (Source: MedWire News - Psychiatry)
Source: MedWire News - Psychiatry - February 7, 2014 Category: Psychiatry Source Type: news

Sleep disturbances could be bipolar disorder treatment target
Both objective and subjective features of sleep differ between people with bipolar disorder who are currently euthymic and healthy controls, a case–control study has found. (Source: MedWire News - Psychiatry)
Source: MedWire News - Psychiatry - February 7, 2014 Category: Psychiatry Source Type: news

Cognitive therapy promising for patients who shun antipsychotics
Cognitive behavioural therapy is a promising option for patients with schizophrenia who refuse to take antipsychotics, show the findings of a pilot randomised trial. (Source: MedWire News - Psychiatry)
Source: MedWire News - Psychiatry - February 6, 2014 Category: Psychiatry Source Type: news

Maternal influenza link to bipolar disorder refined
Research suggests that maternal influenza during pregnancy may increase the risk for bipolar disorder with psychotic features in offspring, rather than being associated with bipolar disorder per se. (Source: MedWire News - Psychiatry)
Source: MedWire News - Psychiatry - February 6, 2014 Category: Psychiatry Source Type: news

Rare and de novo mutations flesh out schizophrenia picture
Two studies in Nature show that rare disruptive and de novo mutations may contribute to the pathophysiology of schizophrenia. (Source: MedWire News - Psychiatry)
Source: MedWire News - Psychiatry - February 5, 2014 Category: Psychiatry Source Type: news

Women with bipolar disorder shoulder heavy medication burden
Study findings highlight the frequent use of complex polypharmacy in patients with bipolar disorder, with women especially likely to be taking multiple medications. (Source: MedWire News - Psychiatry)
Source: MedWire News - Psychiatry - February 5, 2014 Category: Psychiatry Source Type: news

Bipolar disorder could be more common than thought
Bipolar disorder may be underdiagnosed in epidemiological surveys, say researchers who studied data from the World Mental Health surveys. (Source: MedWire News - Psychiatry)
Source: MedWire News - Psychiatry - February 4, 2014 Category: Psychiatry Source Type: news

10-minute neurocognitive measure valid in schizophrenia
Canadian researchers have developed a 10-minute tool that they claim can “rapidly, easily, and validly” assess global neurocognition in people with schizophrenia. (Source: MedWire News - Psychiatry)
Source: MedWire News - Psychiatry - February 4, 2014 Category: Psychiatry Source Type: news

Depression severity marks suicide risk in bipolar patients
The likelihood for suicide ideation among patients with bipolar depression increases with the severity of the episode, shows a study in Indian patients. (Source: MedWire News - Psychiatry)
Source: MedWire News - Psychiatry - February 3, 2014 Category: Psychiatry Source Type: news

Computerized cognitive training shows early promise in schizophrenia
Home-based computerized cognitive training has shown promise as a treatment for young people with schizophrenia, results of a randomized trial indicate. (Source: MedWire News - Psychiatry)
Source: MedWire News - Psychiatry - January 31, 2014 Category: Psychiatry Source Type: news

Psychiatrists urged to monitor metabolic changes in psychosis patients
Japanese psychiatrists are largely aware of the metabolic abnormalities that may arise from antipsychotic treatment, but most do not monitor their patients sufficiently, research shows. (Source: MedWire News - Psychiatry)
Source: MedWire News - Psychiatry - January 30, 2014 Category: Psychiatry Source Type: news

Simple hypomania checklist detects bipolar II disorder
A 15-item hypomania checklist has shown potential for differentiating bipolar disorder, particularly type II, from major depressive disorder. (Source: MedWire News - Psychiatry)
Source: MedWire News - Psychiatry - January 30, 2014 Category: Psychiatry Source Type: news

Impaired cognitive insight linked to delusions in psychosis risk
High levels of self-certainty, one aspect of cognitive insight, are associated with the presence of delusional symptoms in people with at-risk mental states, a study shows. (Source: MedWire News - Psychiatry)
Source: MedWire News - Psychiatry - January 29, 2014 Category: Psychiatry Source Type: news

Susceptible loci identified for bipolar I disorder in Taiwanese
Researchers have identified three genetic loci that may be linked to bipolar I disorder risk in Taiwanese individuals. (Source: MedWire News - Psychiatry)
Source: MedWire News - Psychiatry - January 29, 2014 Category: Psychiatry Source Type: news

Continuity of care protects mental health patients
Research shows that seeing the same psychiatrist over time is associated with reduced mortality in patients using mental health services, particularly those with bipolar disorder, major depressive disorder, or schizophrenia. (Source: MedWire News - Psychiatry)
Source: MedWire News - Psychiatry - January 28, 2014 Category: Psychiatry Source Type: news

Hippocampal activity may reflect ‘core’ schizophrenia traits
Hippocampal function may be a useful biomarker for the response of patients with schizophrenia to medication, research suggests. (Source: MedWire News - Psychiatry)
Source: MedWire News - Psychiatry - January 28, 2014 Category: Psychiatry Source Type: news

Attentional biases toward emotion help characterize bipolar disorder
Attentional biases toward emotional images are a key feature of bipolar disorder and may contribute to increased vulnerability and continued maintenance of the condition, researchers report. (Source: MedWire News - Psychiatry)
Source: MedWire News - Psychiatry - January 24, 2014 Category: Psychiatry Source Type: news

Psychosis risk factors have limited predictive power
Factors known to be linked to schizophrenia risk have little predictive power at either the individual or population level, report researchers. (Source: MedWire News - Psychiatry)
Source: MedWire News - Psychiatry - January 24, 2014 Category: Psychiatry Source Type: news