Plasma microRNA test boosts lung cancer screening
The ability to screen for lung cancer is improved by the development of a plasma 24-microRNA signature classifier, research suggests. (Source: MedWire News - Lung Cancer)
Source: MedWire News - Lung Cancer - February 28, 2014 Category: Cancer & Oncology Source Type: news
H4 receptor activation plays part in NSCLC progression
Histamine H4 receptor activation decreases epithelial-to-mesenchymal transmission in non-small-cell lung cancer, Chinese research shows. (Source: MedWire News - Lung Cancer)
Source: MedWire News - Lung Cancer - February 27, 2014 Category: Cancer & Oncology Source Type: news
Novel SCLC tumour suppressor gene discovered
Inactivation of the MYC-associated factor X gene, MAX, may play a significant role in the development of small-cell lung cancer, scientists believe. (Source: MedWire News - Lung Cancer)
Source: MedWire News - Lung Cancer - February 26, 2014 Category: Cancer & Oncology Source Type: news
EGFR–TKI tumour response predicts NSCLC survival
A partial or complete response to epidermal growth factor receptor tyrosine kinase inhibitor therapy is significantly associated with survival in patients with non-small-cell lung cancer, research suggests. (Source: MedWire News - Lung Cancer)
Source: MedWire News - Lung Cancer - February 20, 2014 Category: Cancer & Oncology Source Type: news
Nintedanib plus docetaxel shows second-line efficacy in recurrent NSCLC
Nintedanib plus docetaxel offers significant efficacy in patients with non-small-cell lung cancer who experience disease progression after first-line chemotherapy, phase III study results show. (Source: MedWire News - Lung Cancer)
Source: MedWire News - Lung Cancer - February 19, 2014 Category: Cancer & Oncology Source Type: news
Afatinib ‘first line’ for advanced mutation-positive lung cancer
Afatinib should be given as a first-line treatment for Asian patients with advanced, epidermal growth factor receptor mutation-positive, non-small-cell lung cancer, researchers recommend. (Source: MedWire News - Lung Cancer)
Source: MedWire News - Lung Cancer - February 17, 2014 Category: Cancer & Oncology Source Type: news
Splicing findings offer lung cancer clues
Researchers from Spain have identified several new splicing events regulated by the oncogenic splicing factor SRSF1 in lung cancer, suggesting that their dysregulation is involved in the pathogenesis of the disease. (Source: MedWire News - Lung Cancer)
Source: MedWire News - Lung Cancer - February 4, 2014 Category: Cancer & Oncology Source Type: news
Primary tumor, node location important in stage III NSCLC prognosis
Researchers from Japan say that classifying clinical mediastinal lymph node status based on the location of the primary tumor and the node involved could improve prognosis in stage III non-small-cell lung cancer compared with pathologic node status. (Source: MedWire News - Lung Cancer)
Source: MedWire News - Lung Cancer - February 3, 2014 Category: Cancer & Oncology Source Type: news
Mesothelin expression prognostic in lung adenocarcinoma
Mesothelin expression is a significant predictor for tumor aggression in patients with lung adenocarcinoma, suggest study findings published in Clinical Cancer Research. (Source: MedWire News - Lung Cancer)
Source: MedWire News - Lung Cancer - January 31, 2014 Category: Cancer & Oncology Source Type: news
RNAi-based screening offers MPM treatment hope
Research using RNA interference-based screening has identified several potential targets for the treatment of malignant pleural mesothelioma. (Source: MedWire News - Lung Cancer)
Source: MedWire News - Lung Cancer - January 31, 2014 Category: Cancer & Oncology Source Type: news
Everolimus fails to boost advanced NSCLC response
Phase II trial findings have ruled out a combination of erlotinib and everolimus for advanced non-small-cell lung cancer patients with progression after chemotherapy. (Source: MedWire News - Lung Cancer)
Source: MedWire News - Lung Cancer - January 28, 2014 Category: Cancer & Oncology Source Type: news
South Korean lung SCC genetic secrets revealed
Close examination of DNA taken from squamous cell carcinoma of the lung in South Korean patients has identified a gene fusion that may be targeted by current treatments, scientists say. (Source: MedWire News - Lung Cancer)
Source: MedWire News - Lung Cancer - January 27, 2014 Category: Cancer & Oncology Source Type: news
Novel HER2 mutation identified in familial lung adenocarcinomas
Researchers have identified a novel germline mutation in the transmembrane domain of the human epidermal growth factor receptor 2 gene in familial lung adenocarcinomas. (Source: MedWire News - Lung Cancer)
Source: MedWire News - Lung Cancer - January 24, 2014 Category: Cancer & Oncology Source Type: news
Immunotherapy maintenance shows promise in NSCLC
Results from a phase III trial have shown that tecemotide is no more effective than placebo as maintenance therapy in patients with non-small-cell lung cancer. (Source: MedWire News - Lung Cancer)
Source: MedWire News - Lung Cancer - January 24, 2014 Category: Cancer & Oncology Source Type: news
Etoposide plus cisplatin remains best for limited-stage SCLC
Etoposide plus cisplatin, given alongside accelerated hyperfractionated thoracic radiotherapy, remains the gold standard regimen for patients with limited-stage small-cell lung cancer, Japanese researchers say. (Source: MedWire News - Lung Cancer)
Source: MedWire News - Lung Cancer - January 23, 2014 Category: Cancer & Oncology Source Type: news
